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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANGEL2
Full Name:
Protein angel homolog 2
Alias:
ANGE2; angel 2; FLJ12793; KIAA0759L
Type:
Mass (Da):
62340
Number AA:
UniProt ID:
Q5VTE6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y21
C
V
V
G
R
G
R
Y
P
M
F
P
H
H
S
Site 2
S30
M
F
P
H
H
S
R
S
L
G
R
D
W
T
T
Site 3
T36
R
S
L
G
R
D
W
T
T
P
W
E
N
L
Q
Site 4
T37
S
L
G
R
D
W
T
T
P
W
E
N
L
Q
R
Site 5
Y66
G
H
Y
S
R
A
P
Y
P
Y
F
S
S
R
H
Site 6
Y68
Y
S
R
A
P
Y
P
Y
F
S
S
R
H
F
S
Site 7
S70
R
A
P
Y
P
Y
F
S
S
R
H
F
S
L
N
Site 8
Y92
E
S
R
T
Q
F
Q
Y
C
N
W
R
P
D
N
Site 9
S101
N
W
R
P
D
N
L
S
Q
T
S
L
I
H
L
Site 10
T103
R
P
D
N
L
S
Q
T
S
L
I
H
L
S
S
Site 11
S104
P
D
N
L
S
Q
T
S
L
I
H
L
S
S
Y
Site 12
Y111
S
L
I
H
L
S
S
Y
V
M
N
A
E
G
D
Site 13
S121
N
A
E
G
D
E
P
S
S
K
R
R
K
H
Q
Site 14
S122
A
E
G
D
E
P
S
S
K
R
R
K
H
Q
G
Site 15
Y137
V
I
K
R
N
W
E
Y
I
C
S
H
D
K
E
Site 16
S161
V
D
P
K
C
E
D
S
E
N
K
F
D
F
S
Site 17
S168
S
E
N
K
F
D
F
S
V
M
S
Y
N
I
L
Site 18
S171
K
F
D
F
S
V
M
S
Y
N
I
L
S
Q
D
Site 19
S176
V
M
S
Y
N
I
L
S
Q
D
L
L
E
D
N
Site 20
Y187
L
E
D
N
S
H
L
Y
R
H
C
R
R
P
V
Site 21
Y226
Q
E
V
Q
E
D
H
Y
G
A
E
I
R
P
S
Site 22
S233
Y
G
A
E
I
R
P
S
L
E
S
L
G
Y
H
Site 23
S236
E
I
R
P
S
L
E
S
L
G
Y
H
C
E
Y
Site 24
Y239
P
S
L
E
S
L
G
Y
H
C
E
Y
K
M
R
Site 25
Y243
S
L
G
Y
H
C
E
Y
K
M
R
T
G
R
K
Site 26
S279
E
F
F
R
P
D
I
S
L
L
D
R
D
N
V
Site 27
Y313
V
A
N
T
H
L
L
Y
N
P
R
R
G
D
I
Site 28
S358
D
F
N
S
V
P
G
S
P
L
Y
S
F
I
K
Site 29
Y361
S
V
P
G
S
P
L
Y
S
F
I
K
E
G
K
Site 30
S362
V
P
G
S
P
L
Y
S
F
I
K
E
G
K
L
Site 31
S380
G
L
P
I
G
K
V
S
G
Q
E
Q
S
S
R
Site 32
S385
K
V
S
G
Q
E
Q
S
S
R
G
Q
R
I
L
Site 33
S393
S
R
G
Q
R
I
L
S
I
P
I
W
P
P
N
Site 34
Y409
G
I
S
Q
N
C
V
Y
E
V
Q
Q
V
P
K
Site 35
T420
Q
V
P
K
V
E
K
T
D
S
D
L
T
Q
T
Site 36
S422
P
K
V
E
K
T
D
S
D
L
T
Q
T
Q
L
Site 37
T425
E
K
T
D
S
D
L
T
Q
T
Q
L
K
Q
T
Site 38
T437
K
Q
T
E
V
L
V
T
A
E
K
L
S
S
N
Site 39
S443
V
T
A
E
K
L
S
S
N
L
Q
H
H
F
S
Site 40
S450
S
N
L
Q
H
H
F
S
L
S
S
V
Y
S
H
Site 41
S456
F
S
L
S
S
V
Y
S
H
Y
F
P
D
T
G
Site 42
Y458
L
S
S
V
Y
S
H
Y
F
P
D
T
G
I
P
Site 43
T462
Y
S
H
Y
F
P
D
T
G
I
P
E
V
T
T
Site 44
T468
D
T
G
I
P
E
V
T
T
C
H
S
R
S
A
Site 45
Y480
R
S
A
I
T
V
D
Y
I
F
Y
S
A
E
K
Site 46
Y483
I
T
V
D
Y
I
F
Y
S
A
E
K
E
D
V
Site 47
S484
T
V
D
Y
I
F
Y
S
A
E
K
E
D
V
A
Site 48
T520
L
T
E
Q
D
L
W
T
V
N
G
L
P
N
E
Site 49
S531
L
P
N
E
N
N
S
S
D
H
L
P
L
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation