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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C1orf164
Full Name:
E3 ubiquitin-protein ligase RNF220
Alias:
CA164; FLJ10597; Ring finger protein 220; RING finger protein C1orf164
Type:
Unknown function
Mass (Da):
62765
Number AA:
566
UniProt ID:
Q5VTB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
F
K
M
E
N
S
S
Y
L
P
N
P
L
A
S
Site 2
S35
L
A
S
T
A
E
A
S
R
D
A
S
I
P
C
Site 3
S39
A
E
A
S
R
D
A
S
I
P
C
Q
Q
P
R
Site 4
S53
R
P
F
G
V
P
V
S
V
D
K
D
V
H
I
Site 5
T63
K
D
V
H
I
P
F
T
N
G
S
Y
T
F
A
Site 6
Y67
I
P
F
T
N
G
S
Y
T
F
A
S
M
Y
H
Site 7
T68
P
F
T
N
G
S
Y
T
F
A
S
M
Y
H
R
Site 8
Y73
S
Y
T
F
A
S
M
Y
H
R
Q
G
G
V
P
Site 9
T82
R
Q
G
G
V
P
G
T
F
A
N
R
D
F
P
Site 10
S91
A
N
R
D
F
P
P
S
L
L
H
L
H
P
Q
Site 11
T107
A
P
P
N
L
D
C
T
P
I
S
M
L
N
H
Site 12
S125
G
A
F
R
P
F
A
S
T
E
D
R
E
S
Y
Site 13
T126
A
F
R
P
F
A
S
T
E
D
R
E
S
Y
Q
Site 14
S131
A
S
T
E
D
R
E
S
Y
Q
S
A
F
T
P
Site 15
Y132
S
T
E
D
R
E
S
Y
Q
S
A
F
T
P
A
Site 16
S134
E
D
R
E
S
Y
Q
S
A
F
T
P
A
K
R
Site 17
T137
E
S
Y
Q
S
A
F
T
P
A
K
R
L
K
N
Site 18
T148
R
L
K
N
C
H
D
T
E
S
P
H
L
R
F
Site 19
S150
K
N
C
H
D
T
E
S
P
H
L
R
F
S
D
Site 20
S156
E
S
P
H
L
R
F
S
D
A
D
G
K
E
Y
Site 21
Y163
S
D
A
D
G
K
E
Y
D
F
G
T
Q
L
P
Site 22
T167
G
K
E
Y
D
F
G
T
Q
L
P
S
S
S
P
Site 23
S171
D
F
G
T
Q
L
P
S
S
S
P
G
S
L
K
Site 24
S172
F
G
T
Q
L
P
S
S
S
P
G
S
L
K
V
Site 25
S173
G
T
Q
L
P
S
S
S
P
G
S
L
K
V
D
Site 26
S176
L
P
S
S
S
P
G
S
L
K
V
D
D
T
G
Site 27
T182
G
S
L
K
V
D
D
T
G
K
K
I
F
A
V
Site 28
S190
G
K
K
I
F
A
V
S
G
L
I
S
D
R
E
Site 29
S194
F
A
V
S
G
L
I
S
D
R
E
A
S
S
S
Site 30
S199
L
I
S
D
R
E
A
S
S
S
P
E
D
R
N
Site 31
S201
S
D
R
E
A
S
S
S
P
E
D
R
N
D
R
Site 32
S234
C
Q
V
L
L
R
P
S
E
L
Q
E
H
M
E
Site 33
S252
E
Q
L
A
Q
L
P
S
S
K
N
S
L
L
K
Site 34
S253
Q
L
A
Q
L
P
S
S
K
N
S
L
L
K
D
Site 35
S256
Q
L
P
S
S
K
N
S
L
L
K
D
A
M
A
Site 36
T266
K
D
A
M
A
P
G
T
P
K
S
L
L
L
S
Site 37
S269
M
A
P
G
T
P
K
S
L
L
L
S
A
S
I
Site 38
S273
T
P
K
S
L
L
L
S
A
S
I
K
R
E
G
Site 39
S275
K
S
L
L
L
S
A
S
I
K
R
E
G
E
S
Site 40
S282
S
I
K
R
E
G
E
S
P
T
A
S
P
H
S
Site 41
T284
K
R
E
G
E
S
P
T
A
S
P
H
S
S
A
Site 42
S286
E
G
E
S
P
T
A
S
P
H
S
S
A
T
D
Site 43
S289
S
P
T
A
S
P
H
S
S
A
T
D
D
L
H
Site 44
S290
P
T
A
S
P
H
S
S
A
T
D
D
L
H
H
Site 45
T292
A
S
P
H
S
S
A
T
D
D
L
H
H
S
D
Site 46
S298
A
T
D
D
L
H
H
S
D
R
Y
Q
T
F
L
Site 47
Y301
D
L
H
H
S
D
R
Y
Q
T
F
L
R
V
R
Site 48
T303
H
H
S
D
R
Y
Q
T
F
L
R
V
R
A
N
Site 49
T313
R
V
R
A
N
R
Q
T
R
L
N
A
R
I
G
Site 50
S335
D
E
G
Q
R
E
G
S
C
M
A
E
D
D
A
Site 51
Y356
N
N
N
R
F
E
E
Y
E
W
C
G
Q
K
R
Site 52
T367
G
Q
K
R
I
R
A
T
T
L
L
E
G
G
F
Site 53
T368
Q
K
R
I
R
A
T
T
L
L
E
G
G
F
R
Site 54
S383
G
S
G
F
I
M
C
S
G
K
E
N
P
D
S
Site 55
S390
S
G
K
E
N
P
D
S
D
A
D
L
D
V
D
Site 56
T401
L
D
V
D
G
D
D
T
L
E
Y
G
K
P
Q
Site 57
Y404
D
G
D
D
T
L
E
Y
G
K
P
Q
Y
T
E
Site 58
Y409
L
E
Y
G
K
P
Q
Y
T
E
A
D
V
I
P
Site 59
S442
V
L
N
G
G
P
P
S
T
R
I
T
P
E
F
Site 60
T446
G
P
P
S
T
R
I
T
P
E
F
S
K
W
A
Site 61
S450
T
R
I
T
P
E
F
S
K
W
A
S
D
E
M
Site 62
S454
P
E
F
S
K
W
A
S
D
E
M
P
S
T
S
Site 63
S459
W
A
S
D
E
M
P
S
T
S
N
G
E
S
S
Site 64
T460
A
S
D
E
M
P
S
T
S
N
G
E
S
S
K
Site 65
S461
S
D
E
M
P
S
T
S
N
G
E
S
S
K
Q
Site 66
S465
P
S
T
S
N
G
E
S
S
K
Q
E
A
M
Q
Site 67
S466
S
T
S
N
G
E
S
S
K
Q
E
A
M
Q
K
Site 68
T474
K
Q
E
A
M
Q
K
T
C
K
N
S
D
I
E
Site 69
T491
T
E
D
S
A
V
T
T
F
E
A
L
K
A
R
Site 70
S507
R
E
L
E
R
Q
L
S
R
G
D
R
Y
K
C
Site 71
Y512
Q
L
S
R
G
D
R
Y
K
C
L
I
C
M
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation