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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM22D
Full Name:
Protein FAM22D
Alias:
Type:
Mass (Da):
86276
Number AA:
806
UniProt ID:
Q5VT03
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
S
H
C
G
N
C
Q
T
A
V
V
S
A
Q
P
Site 2
S53
A
Q
P
E
G
M
A
S
N
G
A
Y
P
A
L
Site 3
T112
V
L
S
N
F
P
S
T
P
L
V
T
E
Q
D
Site 4
S124
E
Q
D
G
C
G
P
S
G
A
G
A
S
N
V
Site 5
S129
G
P
S
G
A
G
A
S
N
V
F
V
Q
M
R
Site 6
S202
Q
A
C
E
G
G
W
S
Q
G
L
P
L
P
P
Site 7
S222
A
Q
L
P
P
I
V
S
Q
G
N
A
G
P
W
Site 8
S238
Q
G
A
H
G
E
G
S
L
A
S
S
Q
A
K
Site 9
S242
G
E
G
S
L
A
S
S
Q
A
K
A
P
P
D
Site 10
S251
A
K
A
P
P
D
D
S
C
N
P
R
S
V
Y
Site 11
S256
D
D
S
C
N
P
R
S
V
Y
E
N
F
R
L
Site 12
Y258
S
C
N
P
R
S
V
Y
E
N
F
R
L
W
Q
Site 13
Y267
N
F
R
L
W
Q
H
Y
K
P
L
A
R
R
H
Site 14
S278
A
R
R
H
L
P
Q
S
P
D
T
E
A
L
S
Site 15
T281
H
L
P
Q
S
P
D
T
E
A
L
S
C
F
L
Site 16
T301
S
L
A
R
R
K
P
T
M
T
L
E
E
G
L
Site 17
T303
A
R
R
K
P
T
M
T
L
E
E
G
L
W
R
Site 18
S319
M
R
E
W
Q
H
T
S
N
F
D
R
M
I
F
Site 19
Y327
N
F
D
R
M
I
F
Y
E
M
A
E
K
F
L
Site 20
T361
Q
C
L
P
P
P
A
T
P
R
L
E
P
R
G
Site 21
Y380
E
V
V
K
Q
P
V
Y
L
P
S
K
A
G
P
Site 22
S383
K
Q
P
V
Y
L
P
S
K
A
G
P
K
A
P
Site 23
T404
P
R
P
Q
R
P
V
T
K
A
R
R
P
P
P
Site 24
T419
R
P
H
R
R
A
E
T
K
A
R
L
P
P
P
Site 25
Y448
P
P
E
V
V
Q
E
Y
V
D
I
M
E
E
L
Site 26
T463
L
G
P
S
L
G
A
T
G
E
P
E
K
Q
R
Site 27
T484
Q
P
Q
E
E
D
W
T
P
P
D
P
G
L
L
Site 28
S492
P
P
D
P
G
L
L
S
Y
T
D
K
L
C
S
Site 29
Y493
P
D
P
G
L
L
S
Y
T
D
K
L
C
S
Q
Site 30
S499
S
Y
T
D
K
L
C
S
Q
K
D
F
V
T
K
Site 31
S521
Q
F
L
E
E
L
L
S
P
D
P
Q
M
D
F
Site 32
S532
Q
M
D
F
L
A
L
S
Q
E
L
E
Q
E
E
Site 33
T542
L
E
Q
E
E
G
L
T
L
A
Q
L
V
E
K
Site 34
T568
R
A
A
P
S
R
G
T
A
R
L
D
S
S
S
Site 35
S573
R
G
T
A
R
L
D
S
S
S
S
K
F
A
A
Site 36
S574
G
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Site 37
S575
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
Site 38
S576
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
G
Site 39
T599
Q
Q
G
V
G
M
E
T
C
P
P
Q
T
T
A
Site 40
T604
M
E
T
C
P
P
Q
T
T
A
R
D
S
Q
G
Site 41
T605
E
T
C
P
P
Q
T
T
A
R
D
S
Q
G
R
Site 42
S609
P
Q
T
T
A
R
D
S
Q
G
R
G
R
A
H
Site 43
T617
Q
G
R
G
R
A
H
T
G
M
A
R
S
K
D
Site 44
T643
G
L
R
A
A
R
P
T
S
P
P
Q
D
H
R
Site 45
S644
L
R
A
A
R
P
T
S
P
P
Q
D
H
R
P
Site 46
T652
P
P
Q
D
H
R
P
T
C
P
G
V
G
T
K
Site 47
S668
A
L
D
L
P
G
G
S
P
V
R
E
S
H
G
Site 48
S673
G
G
S
P
V
R
E
S
H
G
L
A
Q
G
S
Site 49
S681
H
G
L
A
Q
G
S
S
E
E
E
E
L
P
S
Site 50
S688
S
E
E
E
E
L
P
S
L
A
F
L
L
G
S
Site 51
S695
S
L
A
F
L
L
G
S
Q
H
K
L
L
P
W
Site 52
S712
P
Q
S
P
V
P
A
S
G
L
L
S
P
E
K
Site 53
S716
V
P
A
S
G
L
L
S
P
E
K
W
G
P
Q
Site 54
S728
G
P
Q
G
T
H
Q
S
P
S
A
E
R
R
G
Site 55
S730
Q
G
T
H
Q
S
P
S
A
E
R
R
G
L
N
Site 56
S741
R
G
L
N
L
A
P
S
P
A
N
K
A
K
K
Site 57
S754
K
K
R
P
L
F
G
S
L
S
P
A
E
K
T
Site 58
S756
R
P
L
F
G
S
L
S
P
A
E
K
T
P
H
Site 59
T761
S
L
S
P
A
E
K
T
P
H
P
G
P
G
L
Site 60
S771
P
G
P
G
L
R
V
S
G
E
Q
S
L
T
W
Site 61
S775
L
R
V
S
G
E
Q
S
L
T
W
G
L
G
G
Site 62
T777
V
S
G
E
Q
S
L
T
W
G
L
G
G
P
S
Site 63
S784
T
W
G
L
G
G
P
S
Q
S
Q
K
R
K
G
Site 64
S786
G
L
G
G
P
S
Q
S
Q
K
R
K
G
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation