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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MANEAL
Full Name:
Glycoprotein endo-alpha-1,2-mannosidase-like protein
Alias:
Type:
Mass (Da):
51317
Number AA:
457
UniProt ID:
Q5VSG8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T77
P
P
P
P
P
P
R
T
A
D
P
G
G
S
P
Site 2
S83
R
T
A
D
P
G
G
S
P
G
P
A
P
A
E
Site 3
S98
A
E
P
A
P
V
Q
S
L
R
V
Y
S
D
L
Site 4
Y102
P
V
Q
S
L
R
V
Y
S
D
L
H
A
F
Y
Site 5
S103
V
Q
S
L
R
V
Y
S
D
L
H
A
F
Y
Y
Site 6
Y109
Y
S
D
L
H
A
F
Y
Y
S
W
Y
G
S
P
Site 7
Y110
S
D
L
H
A
F
Y
Y
S
W
Y
G
S
P
R
Site 8
Y113
H
A
F
Y
Y
S
W
Y
G
S
P
R
R
E
G
Site 9
S138
P
H
W
D
P
K
I
S
A
S
Y
P
R
G
R
Site 10
S140
W
D
P
K
I
S
A
S
Y
P
R
G
R
H
S
Site 11
Y141
D
P
K
I
S
A
S
Y
P
R
G
R
H
S
P
Site 12
S147
S
Y
P
R
G
R
H
S
P
P
D
D
L
G
S
Site 13
S154
S
P
P
D
D
L
G
S
S
F
Y
P
E
L
G
Site 14
S155
P
P
D
D
L
G
S
S
F
Y
P
E
L
G
P
Site 15
Y157
D
D
L
G
S
S
F
Y
P
E
L
G
P
Y
S
Site 16
Y163
F
Y
P
E
L
G
P
Y
S
S
R
D
P
E
V
Site 17
S164
Y
P
E
L
G
P
Y
S
S
R
D
P
E
V
L
Site 18
S165
P
E
L
G
P
Y
S
S
R
D
P
E
V
L
R
Site 19
S203
A
D
D
N
G
E
P
S
D
D
L
V
P
A
I
Site 20
T235
Y
K
G
R
D
D
I
T
V
H
D
N
I
K
Y
Site 21
Y242
T
V
H
D
N
I
K
Y
I
I
D
T
Y
G
S
Site 22
T246
N
I
K
Y
I
I
D
T
Y
G
S
H
G
A
F
Site 23
Y247
I
K
Y
I
I
D
T
Y
G
S
H
G
A
F
Y
Site 24
Y254
Y
G
S
H
G
A
F
Y
R
Y
K
N
S
M
G
Site 25
Y256
S
H
G
A
F
Y
R
Y
K
N
S
M
G
K
S
Site 26
S259
A
F
Y
R
Y
K
N
S
M
G
K
S
L
P
L
Site 27
S272
P
L
F
Y
I
Y
D
S
Y
L
T
S
P
E
A
Site 28
Y273
L
F
Y
I
Y
D
S
Y
L
T
S
P
E
A
W
Site 29
S276
I
Y
D
S
Y
L
T
S
P
E
A
W
A
H
L
Site 30
T285
E
A
W
A
H
L
L
T
P
N
G
P
H
S
I
Site 31
S291
L
T
P
N
G
P
H
S
I
R
N
T
P
Y
D
Site 32
T295
G
P
H
S
I
R
N
T
P
Y
D
G
V
F
I
Site 33
Y323
A
A
G
F
D
G
M
Y
T
Y
F
A
S
N
G
Site 34
Y325
G
F
D
G
M
Y
T
Y
F
A
S
N
G
F
S
Site 35
S332
Y
F
A
S
N
G
F
S
F
G
S
S
H
Q
N
Site 36
Y362
I
P
S
V
G
P
G
Y
I
D
T
S
I
R
P
Site 37
T365
V
G
P
G
Y
I
D
T
S
I
R
P
W
N
N
Site 38
Y383
R
N
R
V
N
G
K
Y
Y
E
T
A
L
Q
A
Site 39
S400
T
V
R
P
E
I
V
S
I
T
S
F
N
E
W
Site 40
S403
P
E
I
V
S
I
T
S
F
N
E
W
H
E
G
Site 41
T421
E
K
A
I
P
K
K
T
P
T
R
L
Y
L
D
Site 42
Y426
K
K
T
P
T
R
L
Y
L
D
Y
L
P
H
Q
Site 43
Y429
P
T
R
L
Y
L
D
Y
L
P
H
Q
P
S
L
Site 44
S435
D
Y
L
P
H
Q
P
S
L
Y
L
E
L
T
R
Site 45
Y437
L
P
H
Q
P
S
L
Y
L
E
L
T
R
R
W
Site 46
T441
P
S
L
Y
L
E
L
T
R
R
W
A
E
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation