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Updated November 2019
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Protein Info
Short Name:
VPS13D
Full Name:
Vacuolar protein sorting-associated protein 13D
Alias:
FLJ10619; KIAA0453; Vacuolar protein sorting 13 D; Vacuolar protein sorting 13D; Vacuolar protein sorting-associated protein 13D: Vacuolar protein sorting-associated protein 13D
Type:
Vesicle protein
Mass (Da):
491845
Number AA:
4387
UniProt ID:
Q5THJ4
International Prot ID:
IPI00784473
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008104
GO:0033036
GO:0051179
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
L
N
T
Y
L
G
K
Y
V
N
N
L
N
T
D
Site 2
Y71
V
T
L
Q
I
P
F
Y
R
P
H
V
D
P
W
Site 3
Y132
R
Q
Q
K
G
E
S
Y
W
Y
S
V
T
A
S
Site 4
Y134
Q
K
G
E
S
Y
W
Y
S
V
T
A
S
V
V
Site 5
S135
K
G
E
S
Y
W
Y
S
V
T
A
S
V
V
T
Site 6
T164
L
R
F
E
D
G
V
T
N
P
S
H
P
F
A
Site 7
S229
L
Q
E
A
M
A
R
S
M
E
S
R
S
H
H
Site 8
S234
A
R
S
M
E
S
R
S
H
H
Y
V
L
E
P
Site 9
Y237
M
E
S
R
S
H
H
Y
V
L
E
P
V
F
A
Site 10
S253
A
L
L
K
R
N
C
S
K
K
P
L
R
S
R
Site 11
S259
C
S
K
K
P
L
R
S
R
H
S
P
R
I
D
Site 12
S262
K
P
L
R
S
R
H
S
P
R
I
D
C
D
I
Site 13
S279
E
T
I
P
L
K
L
S
Q
L
Q
Y
R
Q
I
Site 14
Y283
L
K
L
S
Q
L
Q
Y
R
Q
I
M
E
F
L
Site 15
Y328
F
A
L
N
A
N
L
Y
E
I
R
E
Q
R
K
Site 16
S351
H
R
A
R
D
A
V
S
Y
T
D
K
Y
F
N
Site 17
Y352
R
A
R
D
A
V
S
Y
T
D
K
Y
F
N
K
Site 18
Y356
A
V
S
Y
T
D
K
Y
F
N
K
L
K
G
G
Site 19
S366
K
L
K
G
G
L
L
S
T
D
D
K
E
E
M
Site 20
S381
C
R
I
E
E
E
Q
S
F
E
E
L
K
I
L
Site 21
S405
K
Q
E
E
L
A
E
S
L
R
E
P
Q
F
D
Site 22
S413
L
R
E
P
Q
F
D
S
P
G
A
C
P
G
A
Site 23
Y432
G
G
S
G
M
L
Q
Y
L
Q
S
W
F
P
G
Site 24
Y444
F
P
G
W
G
G
W
Y
G
Q
Q
T
P
E
G
Site 25
T448
G
G
W
Y
G
Q
Q
T
P
E
G
N
V
V
E
Site 26
T473
I
P
E
E
I
L
G
T
E
E
F
F
D
P
T
Site 27
T480
T
E
E
F
F
D
P
T
A
D
A
S
C
M
N
Site 28
T488
A
D
A
S
C
M
N
T
Y
T
K
R
D
H
V
Site 29
T507
N
L
Q
L
Q
R
G
T
V
T
L
L
H
K
E
Site 30
T517
L
L
H
K
E
Q
G
T
P
Q
M
N
E
S
A
Site 31
S539
D
V
K
L
L
A
E
S
L
P
R
R
N
S
S
Site 32
S545
E
S
L
P
R
R
N
S
S
L
L
S
V
R
L
Site 33
S546
S
L
P
R
R
N
S
S
L
L
S
V
R
L
G
Site 34
S549
R
R
N
S
S
L
L
S
V
R
L
G
G
L
F
Site 35
S583
Q
K
E
V
G
R
V
S
Q
S
F
G
L
Q
T
Site 36
S585
E
V
G
R
V
S
Q
S
F
G
L
Q
T
T
S
Site 37
S592
S
F
G
L
Q
T
T
S
A
D
R
S
D
H
Y
Site 38
S596
Q
T
T
S
A
D
R
S
D
H
Y
P
A
A
D
Site 39
Y599
S
A
D
R
S
D
H
Y
P
A
A
D
P
D
G
Site 40
Y613
G
P
V
F
E
M
L
Y
E
R
N
P
A
H
S
Site 41
S620
Y
E
R
N
P
A
H
S
H
F
E
R
R
L
N
Site 42
S629
F
E
R
R
L
N
V
S
T
R
P
L
N
I
I
Site 43
T630
E
R
R
L
N
V
S
T
R
P
L
N
I
I
Y
Site 44
Y650
K
K
V
A
D
F
F
Y
K
G
K
V
H
T
S
Site 45
S657
Y
K
G
K
V
H
T
S
G
F
G
Y
Q
S
E
Site 46
Y661
V
H
T
S
G
F
G
Y
Q
S
E
L
E
L
R
Site 47
S663
T
S
G
F
G
Y
Q
S
E
L
E
L
R
V
A
Site 48
Y677
A
E
A
A
R
R
Q
Y
N
K
L
K
M
Q
T
Site 49
T691
T
K
A
E
I
R
Q
T
L
D
R
L
L
V
G
Site 50
S704
V
G
D
F
I
E
E
S
K
R
W
T
V
R
L
Site 51
T708
I
E
E
S
K
R
W
T
V
R
L
D
I
S
A
Site 52
T744
G
R
M
L
L
T
N
T
Q
D
N
S
R
R
K
Site 53
S748
L
T
N
T
Q
D
N
S
R
R
K
S
R
D
G
Site 54
S752
Q
D
N
S
R
R
K
S
R
D
G
S
A
S
E
Site 55
S756
R
R
K
S
R
D
G
S
A
S
E
E
T
Q
F
Site 56
S758
K
S
R
D
G
S
A
S
E
E
T
Q
F
S
D
Site 57
S764
A
S
E
E
T
Q
F
S
D
D
E
Y
K
T
P
Site 58
Y768
T
Q
F
S
D
D
E
Y
K
T
P
L
A
T
P
Site 59
T770
F
S
D
D
E
Y
K
T
P
L
A
T
P
P
N
Site 60
T774
E
Y
K
T
P
L
A
T
P
P
N
T
P
P
P
Site 61
T778
P
L
A
T
P
P
N
T
P
P
P
E
S
S
S
Site 62
S783
P
N
T
P
P
P
E
S
S
S
S
N
G
E
K
Site 63
S786
P
P
P
E
S
S
S
S
N
G
E
K
T
P
P
Site 64
T791
S
S
S
N
G
E
K
T
P
P
F
S
G
V
E
Site 65
S795
G
E
K
T
P
P
F
S
G
V
E
F
S
E
E
Site 66
S800
P
F
S
G
V
E
F
S
E
E
Q
L
Q
A
H
Site 67
Y814
H
L
M
S
T
K
M
Y
E
R
Y
S
L
S
F
Site 68
S818
T
K
M
Y
E
R
Y
S
L
S
F
M
D
L
Q
Site 69
Y864
Q
L
E
R
R
L
I
Y
T
S
D
P
K
Y
P
Site 70
T865
L
E
R
R
L
I
Y
T
S
D
P
K
Y
P
G
Site 71
S866
E
R
R
L
I
Y
T
S
D
P
K
Y
P
G
A
Site 72
Y870
I
Y
T
S
D
P
K
Y
P
G
A
V
L
S
G
Site 73
S876
K
Y
P
G
A
V
L
S
G
N
L
P
D
L
K
Site 74
T903
N
C
F
A
L
L
T
T
P
E
M
K
T
S
D
Site 75
S909
T
T
P
E
M
K
T
S
D
T
Q
I
K
E
K
Site 76
T911
P
E
M
K
T
S
D
T
Q
I
K
E
K
I
F
Site 77
S926
P
Q
E
E
Q
R
G
S
L
Q
D
S
V
M
N
Site 78
S930
Q
R
G
S
L
Q
D
S
V
M
N
L
T
Q
S
Site 79
S976
E
S
N
G
R
Y
I
S
V
L
K
V
F
G
T
Site 80
Y992
A
H
F
V
K
R
P
Y
D
A
E
V
S
L
T
Site 81
S1022
D
F
D
L
L
M
A
S
H
K
N
L
S
F
D
Site 82
S1027
M
A
S
H
K
N
L
S
F
D
I
P
T
G
S
Site 83
T1032
N
L
S
F
D
I
P
T
G
S
L
R
D
S
R
Site 84
S1034
S
F
D
I
P
T
G
S
L
R
D
S
R
A
Q
Site 85
S1038
P
T
G
S
L
R
D
S
R
A
Q
S
P
V
S
Site 86
S1042
L
R
D
S
R
A
Q
S
P
V
S
G
P
N
V
Site 87
S1045
S
R
A
Q
S
P
V
S
G
P
N
V
A
H
L
Site 88
T1053
G
P
N
V
A
H
L
T
D
G
A
T
L
N
D
Site 89
T1057
A
H
L
T
D
G
A
T
L
N
D
R
S
A
T
Site 90
S1062
G
A
T
L
N
D
R
S
A
T
S
V
S
L
D
Site 91
T1064
T
L
N
D
R
S
A
T
S
V
S
L
D
K
I
Site 92
S1067
D
R
S
A
T
S
V
S
L
D
K
I
L
T
K
Site 93
Y1084
E
S
L
I
K
L
E
Y
Q
F
V
S
S
E
C
Site 94
S1088
K
L
E
Y
Q
F
V
S
S
E
C
P
S
M
N
Site 95
S1089
L
E
Y
Q
F
V
S
S
E
C
P
S
M
N
L
Site 96
S1093
F
V
S
S
E
C
P
S
M
N
L
D
S
T
L
Site 97
S1129
L
I
G
F
L
Q
K
S
F
P
K
E
K
D
D
Site 98
S1138
P
K
E
K
D
D
L
S
P
Q
P
L
M
T
D
Site 99
T1144
L
S
P
Q
P
L
M
T
D
F
E
R
S
F
R
Site 100
S1149
L
M
T
D
F
E
R
S
F
R
E
Q
G
T
Y
Site 101
Y1156
S
F
R
E
Q
G
T
Y
Q
S
T
Y
E
Q
N
Site 102
Y1160
Q
G
T
Y
Q
S
T
Y
E
Q
N
T
E
V
A
Site 103
Y1189
G
M
A
N
R
E
K
Y
G
R
K
I
A
T
A
Site 104
S1197
G
R
K
I
A
T
A
S
I
G
G
T
K
V
N
Site 105
S1206
G
G
T
K
V
N
V
S
M
G
S
T
F
D
M
Site 106
T1226
C
L
Q
L
M
D
L
T
Q
D
N
V
K
N
Q
Site 107
Y1234
Q
D
N
V
K
N
Q
Y
V
V
S
I
G
N
S
Site 108
S1237
V
K
N
Q
Y
V
V
S
I
G
N
S
V
G
Y
Site 109
S1249
V
G
Y
E
N
I
I
S
D
I
G
Y
F
E
S
Site 110
T1273
L
T
E
A
L
S
F
T
F
V
E
R
S
K
Q
Site 111
S1278
S
F
T
F
V
E
R
S
K
Q
E
C
F
L
N
Site 112
S1296
A
S
L
H
Y
N
H
S
A
K
F
L
K
E
L
Site 113
S1306
F
L
K
E
L
T
L
S
M
D
E
L
E
E
N
Site 114
S1320
N
F
R
G
M
L
K
S
A
A
T
K
V
T
T
Site 115
Y1336
L
A
T
K
T
A
E
Y
S
E
M
V
S
L
F
Site 116
S1337
A
T
K
T
A
E
Y
S
E
M
V
S
L
F
E
Site 117
S1341
A
E
Y
S
E
M
V
S
L
F
E
T
P
R
K
Site 118
T1345
E
M
V
S
L
F
E
T
P
R
K
T
R
E
P
Site 119
T1349
L
F
E
T
P
R
K
T
R
E
P
F
I
L
E
Site 120
Y1361
I
L
E
E
N
E
I
Y
G
F
D
L
A
S
S
Site 121
S1387
N
I
E
S
P
V
V
S
I
P
R
K
P
G
S
Site 122
S1394
S
I
P
R
K
P
G
S
P
E
L
L
V
G
H
Site 123
S1417
F
V
A
G
D
D
E
S
R
S
D
R
L
Q
V
Site 124
S1419
A
G
D
D
E
S
R
S
D
R
L
Q
V
E
I
Site 125
Y1432
E
I
K
D
I
K
L
Y
S
L
N
C
T
Q
L
Site 126
T1437
K
L
Y
S
L
N
C
T
Q
L
A
G
R
E
A
Site 127
S1447
A
G
R
E
A
V
G
S
E
G
S
R
M
F
C
Site 128
S1457
S
R
M
F
C
P
P
S
G
S
G
S
A
N
S
Site 129
S1459
M
F
C
P
P
S
G
S
G
S
A
N
S
Q
E
Site 130
S1461
C
P
P
S
G
S
G
S
A
N
S
Q
E
E
A
Site 131
S1464
S
G
S
G
S
A
N
S
Q
E
E
A
H
F
T
Site 132
T1471
S
Q
E
E
A
H
F
T
R
H
D
F
F
E
S
Site 133
S1478
T
R
H
D
F
F
E
S
L
H
R
G
Q
A
F
Site 134
S1506
K
I
P
I
E
R
E
S
E
L
T
F
S
L
S
Site 135
T1509
I
E
R
E
S
E
L
T
F
S
L
S
P
D
D
Site 136
S1511
R
E
S
E
L
T
F
S
L
S
P
D
D
L
G
Site 137
S1513
S
E
L
T
F
S
L
S
P
D
D
L
G
T
S
Site 138
S1520
S
P
D
D
L
G
T
S
S
I
M
K
I
E
G
Site 139
S1521
P
D
D
L
G
T
S
S
I
M
K
I
E
G
K
Site 140
Y1554
Q
T
L
D
N
L
V
Y
S
E
D
L
N
K
Y
Site 141
Y1561
Y
S
E
D
L
N
K
Y
P
A
S
A
T
S
S
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P
C
F
G
Site 294
Y2856
G
Q
S
L
P
L
V
Y
L
R
T
R
S
T
A
Site 295
S2861
L
V
Y
L
R
T
R
S
T
A
S
L
T
N
L
Site 296
T2862
V
Y
L
R
T
R
S
T
A
S
L
T
N
L
E
Site 297
S2864
L
R
T
R
S
T
A
S
L
T
N
L
E
H
Q
Site 298
Y2873
T
N
L
E
H
Q
I
Y
A
R
E
V
K
T
P
Site 299
T2879
I
Y
A
R
E
V
K
T
P
K
R
R
Q
P
F
Site 300
T2909
A
T
L
T
T
T
P
T
R
A
A
L
S
H
S
Site 301
S2914
T
P
T
R
A
A
L
S
H
S
G
S
P
G
V
Site 302
S2916
T
R
A
A
L
S
H
S
G
S
P
G
V
V
P
Site 303
S2918
A
A
L
S
H
S
G
S
P
G
V
V
P
E
G
Site 304
T2928
V
V
P
E
G
N
G
T
F
L
D
D
T
H
N
Site 305
S2937
L
D
D
T
H
N
V
S
E
W
R
E
V
L
T
Site 306
T2963
G
K
L
R
H
R
H
T
H
D
L
R
I
H
Q
Site 307
S2982
V
N
G
W
E
Q
V
S
P
V
S
V
D
K
V
Site 308
S2985
W
E
Q
V
S
P
V
S
V
D
K
V
G
T
F
Site 309
Y2995
K
V
G
T
F
F
R
Y
A
A
P
D
K
N
S
Site 310
S3002
Y
A
A
P
D
K
N
S
S
S
S
T
I
G
S
Site 311
S3003
A
A
P
D
K
N
S
S
S
S
T
I
G
S
P
Site 312
S3004
A
P
D
K
N
S
S
S
S
T
I
G
S
P
S
Site 313
S3005
P
D
K
N
S
S
S
S
T
I
G
S
P
S
S
Site 314
T3006
D
K
N
S
S
S
S
T
I
G
S
P
S
S
R
Site 315
S3009
S
S
S
S
T
I
G
S
P
S
S
R
T
N
I
Site 316
S3011
S
S
T
I
G
S
P
S
S
R
T
N
I
I
H
Site 317
S3012
S
T
I
G
S
P
S
S
R
T
N
I
I
H
P
Site 318
T3059
I
V
R
N
R
L
E
T
P
M
E
L
R
L
D
Site 319
S3067
P
M
E
L
R
L
D
S
P
S
A
P
D
K
P
Site 320
S3069
E
L
R
L
D
S
P
S
A
P
D
K
P
V
V
Site 321
S3094
A
V
P
L
H
L
T
S
W
R
L
Q
A
R
P
Site 322
T3121
H
W
T
N
V
V
K
T
A
E
I
S
S
S
K
Site 323
S3126
V
K
T
A
E
I
S
S
S
K
R
E
C
H
S
Site 324
S3127
K
T
A
E
I
S
S
S
K
R
E
C
H
S
M
Site 325
S3133
S
S
K
R
E
C
H
S
M
D
T
E
K
S
R
Site 326
T3136
R
E
C
H
S
M
D
T
E
K
S
R
F
F
R
Site 327
Y3153
V
A
I
K
K
E
N
Y
P
D
Y
M
P
S
N
Site 328
Y3156
K
K
E
N
Y
P
D
Y
M
P
S
N
I
F
S
Site 329
S3159
N
Y
P
D
Y
M
P
S
N
I
F
S
D
S
A
Site 330
S3163
Y
M
P
S
N
I
F
S
D
S
A
K
Q
I
F
Site 331
T3205
K
G
M
P
I
N
G
T
L
K
P
G
K
E
A
Site 332
S3220
A
L
H
T
A
D
T
S
Q
N
I
E
L
G
V
Site 333
T3244
E
L
L
I
P
P
G
T
Q
N
Y
M
V
R
M
Site 334
Y3247
I
P
P
G
T
Q
N
Y
M
V
R
M
R
L
Y
Site 335
Y3254
Y
M
V
R
M
R
L
Y
D
V
N
R
R
Q
L
Site 336
T3264
N
R
R
Q
L
N
L
T
I
R
I
V
C
R
A
Site 337
S3316
E
E
H
E
L
A
R
S
L
S
P
L
L
F
C
Site 338
Y3324
L
S
P
L
L
F
C
Y
A
D
K
E
Q
P
N
Site 339
T3334
K
E
Q
P
N
L
C
T
M
R
I
G
R
G
I
Site 340
S3354
P
G
W
C
Q
G
F
S
L
D
G
G
S
G
V
Site 341
Y3377
G
N
R
P
G
L
I
Y
N
I
G
I
D
V
K
Site 342
Y3390
V
K
K
G
R
G
R
Y
I
D
T
C
M
V
I
Site 343
Y3402
M
V
I
F
A
P
R
Y
L
L
D
N
K
S
S
Site 344
S3408
R
Y
L
L
D
N
K
S
S
H
K
L
A
F
A
Site 345
T3425
E
F
A
R
G
Q
G
T
A
N
P
E
G
Y
I
Site 346
Y3431
G
T
A
N
P
E
G
Y
I
S
T
L
P
G
S
Site 347
S3433
A
N
P
E
G
Y
I
S
T
L
P
G
S
S
V
Site 348
T3434
N
P
E
G
Y
I
S
T
L
P
G
S
S
V
V
Site 349
S3438
Y
I
S
T
L
P
G
S
S
V
V
F
H
W
P
Site 350
S3439
I
S
T
L
P
G
S
S
V
V
F
H
W
P
R
Site 351
Y3449
F
H
W
P
R
N
D
Y
D
Q
L
L
C
V
R
Site 352
T3501
E
I
T
L
R
G
A
T
Y
R
I
S
F
S
D
Site 353
S3505
R
G
A
T
Y
R
I
S
F
S
D
T
D
Q
L
Site 354
S3507
A
T
Y
R
I
S
F
S
D
T
D
Q
L
P
P
Site 355
T3509
Y
R
I
S
F
S
D
T
D
Q
L
P
P
P
F
Site 356
T3540
V
A
E
P
R
L
R
T
E
V
K
P
M
T
S
Site 357
Y3550
K
P
M
T
S
L
D
Y
A
W
D
E
P
T
L
Site 358
T3556
D
Y
A
W
D
E
P
T
L
P
P
F
I
T
L
Site 359
Y3587
F
Q
D
N
R
Q
L
Y
Y
E
N
F
I
Y
I
Site 360
Y3588
Q
D
N
R
Q
L
Y
Y
E
N
F
I
Y
I
A
Site 361
S3613
G
T
G
R
P
V
A
S
N
K
A
I
T
C
A
Site 362
T3630
V
L
D
V
S
P
K
T
Q
R
V
I
L
K
K
Site 363
S3644
K
K
E
P
G
K
R
S
Q
L
W
R
M
T
G
Site 364
T3650
R
S
Q
L
W
R
M
T
G
T
G
M
L
A
H
Site 365
S3660
G
M
L
A
H
E
G
S
S
V
P
H
N
P
N
Site 366
S3670
P
H
N
P
N
K
P
S
A
A
R
S
T
E
G
Site 367
S3674
N
K
P
S
A
A
R
S
T
E
G
S
A
I
L
Site 368
T3675
K
P
S
A
A
R
S
T
E
G
S
A
I
L
D
Site 369
Y3694
A
A
V
T
D
N
R
Y
E
P
L
M
L
R
K
Site 370
S3707
R
K
P
D
R
R
R
S
T
T
Q
T
W
S
F
Site 371
T3708
K
P
D
R
R
R
S
T
T
Q
T
W
S
F
R
Site 372
T3709
P
D
R
R
R
S
T
T
Q
T
W
S
F
R
E
Site 373
T3711
R
R
R
S
T
T
Q
T
W
S
F
R
E
G
K
Site 374
S3713
R
S
T
T
Q
T
W
S
F
R
E
G
K
L
T
Site 375
S3772
N
Q
K
M
R
P
G
S
G
M
L
S
I
R
V
Site 376
S3776
R
P
G
S
G
M
L
S
I
R
V
I
P
D
G
Site 377
T3791
P
T
R
A
L
Q
I
T
D
F
C
H
R
K
S
Site 378
S3798
T
D
F
C
H
R
K
S
S
R
S
Y
E
V
D
Site 379
S3799
D
F
C
H
R
K
S
S
R
S
Y
E
V
D
E
Site 380
S3801
C
H
R
K
S
S
R
S
Y
E
V
D
E
L
P
Site 381
Y3802
H
R
K
S
S
R
S
Y
E
V
D
E
L
P
V
Site 382
T3810
E
V
D
E
L
P
V
T
E
Q
E
L
Q
K
L
Site 383
T3822
Q
K
L
K
N
P
D
T
E
Q
E
L
E
V
L
Site 384
S3872
T
S
H
M
L
E
L
S
I
Q
D
V
Q
V
D
Site 385
Y3892
T
T
Q
P
F
M
L
Y
V
T
P
L
S
N
E
Site 386
T3894
Q
P
F
M
L
Y
V
T
P
L
S
N
E
N
E
Site 387
S3897
M
L
Y
V
T
P
L
S
N
E
N
E
V
I
E
Site 388
S3920
A
V
K
F
P
S
K
S
A
L
T
N
I
Y
K
Site 389
T3937
M
I
T
A
Q
R
F
T
V
Q
I
E
E
K
L
Site 390
Y3954
K
L
L
S
F
F
G
Y
D
Q
A
E
S
E
V
Site 391
Y3964
A
E
S
E
V
E
K
Y
D
E
N
L
H
E
K
Site 392
T3978
K
T
A
E
Q
G
G
T
P
I
R
Y
Y
F
E
Site 393
Y3982
Q
G
G
T
P
I
R
Y
Y
F
E
N
L
K
I
Site 394
Y3983
G
G
T
P
I
R
Y
Y
F
E
N
L
K
I
S
Site 395
T4033
V
I
N
L
D
P
F
T
R
V
H
P
Y
E
T
Site 396
Y4038
P
F
T
R
V
H
P
Y
E
T
K
E
F
I
I
Site 397
S4058
H
F
Q
E
E
L
L
S
Q
A
A
R
I
L
G
Site 398
T4101
G
G
L
I
R
N
V
T
H
G
V
S
N
S
A
Site 399
T4114
S
A
A
K
F
A
G
T
L
S
D
G
L
G
K
Site 400
S4116
A
K
F
A
G
T
L
S
D
G
L
G
K
T
M
Site 401
T4122
L
S
D
G
L
G
K
T
M
D
N
R
H
Q
S
Site 402
Y4133
R
H
Q
S
E
R
E
Y
I
R
Y
H
A
A
T
Site 403
Y4136
S
E
R
E
Y
I
R
Y
H
A
A
T
S
G
E
Site 404
T4140
Y
I
R
Y
H
A
A
T
S
G
E
H
L
V
A
Site 405
T4173
S
T
V
E
G
V
K
T
E
G
G
V
S
G
F
Site 406
T4213
T
A
Q
A
V
R
D
T
A
T
L
S
G
P
R
Site 407
T4215
Q
A
V
R
D
T
A
T
L
S
G
P
R
T
Q
Site 408
S4217
V
R
D
T
A
T
L
S
G
P
R
T
Q
A
Q
Site 409
T4221
A
T
L
S
G
P
R
T
Q
A
Q
R
V
R
K
Site 410
T4233
V
R
K
P
R
C
C
T
G
P
Q
G
L
L
P
Site 411
Y4242
P
Q
G
L
L
P
R
Y
S
E
S
Q
A
E
G
Site 412
S4243
Q
G
L
L
P
R
Y
S
E
S
Q
A
E
G
Q
Site 413
S4245
L
L
P
R
Y
S
E
S
Q
A
E
G
Q
E
Q
Site 414
S4288
K
A
V
Y
F
L
K
S
G
D
Y
V
D
R
E
Site 415
Y4291
Y
F
L
K
S
G
D
Y
V
D
R
E
A
I
F
Site 416
Y4307
E
V
K
Y
D
D
L
Y
H
C
L
V
S
K
D
Site 417
Y4319
S
K
D
H
G
K
V
Y
V
Q
V
T
K
K
A
Site 418
S4328
Q
V
T
K
K
A
V
S
T
S
S
G
V
S
I
Site 419
S4330
T
K
K
A
V
S
T
S
S
G
V
S
I
P
G
Site 420
S4331
K
K
A
V
S
T
S
S
G
V
S
I
P
G
P
Site 421
S4334
V
S
T
S
S
G
V
S
I
P
G
P
S
H
Q
Site 422
S4339
G
V
S
I
P
G
P
S
H
Q
K
P
M
V
H
Site 423
S4357
E
V
L
A
V
K
L
S
Q
E
I
N
Y
A
K
Site 424
S4365
Q
E
I
N
Y
A
K
S
L
Y
Y
E
Q
Q
L
Site 425
Y4367
I
N
Y
A
K
S
L
Y
Y
E
Q
Q
L
M
L
Site 426
S4377
Q
Q
L
M
L
R
L
S
E
N
R
E
Q
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation