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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF618
Full Name:
Zinc finger protein 618
Alias:
KIAA1952; Zinc finger 618; Zn618; Znf618
Type:
Transcription regulation
Mass (Da):
104960
Number AA:
UniProt ID:
Q5T7W0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0046983
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
P
Q
A
D
G
A
S
A
A
G
R
K
S
T
Site 2
S22
A
S
A
A
G
R
K
S
T
A
S
R
E
R
L
Site 3
T23
S
A
A
G
R
K
S
T
A
S
R
E
R
L
K
Site 4
S25
A
G
R
K
S
T
A
S
R
E
R
L
K
R
S
Site 5
S32
S
R
E
R
L
K
R
S
Q
K
S
T
K
V
E
Site 6
S35
R
L
K
R
S
Q
K
S
T
K
V
E
G
P
E
Site 7
T36
L
K
R
S
Q
K
S
T
K
V
E
G
P
E
P
Site 8
S49
E
P
V
P
A
E
A
S
L
S
A
E
Q
G
T
Site 9
S51
V
P
A
E
A
S
L
S
A
E
Q
G
T
M
T
Site 10
Y70
K
T
E
L
P
D
D
Y
I
Q
E
V
I
W
Q
Site 11
T92
K
A
V
S
K
D
G
T
S
D
V
P
A
E
I
Site 12
S93
A
V
S
K
D
G
T
S
D
V
P
A
E
I
C
Site 13
T111
G
G
V
R
N
Q
Q
T
L
D
G
K
A
P
E
Site 14
S120
D
G
K
A
P
E
G
S
P
H
G
G
S
V
R
Site 15
S125
E
G
S
P
H
G
G
S
V
R
S
R
Y
S
G
Site 16
S128
P
H
G
G
S
V
R
S
R
Y
S
G
T
W
I
Site 17
Y130
G
G
S
V
R
S
R
Y
S
G
T
W
I
F
D
Site 18
S131
G
S
V
R
S
R
Y
S
G
T
W
I
F
D
Q
Site 19
Y142
I
F
D
Q
A
L
R
Y
A
S
G
S
Y
E
C
Site 20
S144
D
Q
A
L
R
Y
A
S
G
S
Y
E
C
G
I
Site 21
Y147
L
R
Y
A
S
G
S
Y
E
C
G
I
C
G
K
Site 22
T172
H
V
R
A
H
R
D
T
E
A
T
S
G
E
G
Site 23
S181
A
T
S
G
E
G
A
S
Q
S
N
N
F
R
Y
Site 24
S183
S
G
E
G
A
S
Q
S
N
N
F
R
Y
T
C
Site 25
Y188
S
Q
S
N
N
F
R
Y
T
C
D
I
C
G
K
Site 26
Y200
C
G
K
K
Y
K
Y
Y
S
C
F
Q
E
H
R
Site 27
T253
F
Q
K
I
G
P
K
T
G
N
Y
T
C
E
F
Site 28
Y256
I
G
P
K
T
G
N
Y
T
C
E
F
C
G
K
Site 29
Y267
F
C
G
K
Q
Y
K
Y
Y
T
P
Y
Q
E
H
Site 30
Y268
C
G
K
Q
Y
K
Y
Y
T
P
Y
Q
E
H
V
Site 31
T269
G
K
Q
Y
K
Y
Y
T
P
Y
Q
E
H
V
A
Site 32
Y271
Q
Y
K
Y
Y
T
P
Y
Q
E
H
V
A
L
H
Site 33
T295
E
P
P
D
D
P
D
T
G
S
E
C
S
H
P
Site 34
S297
P
D
D
P
D
T
G
S
E
C
S
H
P
E
V
Site 35
S300
P
D
T
G
S
E
C
S
H
P
E
V
S
P
S
Site 36
S305
E
C
S
H
P
E
V
S
P
S
P
R
F
V
A
Site 37
S307
S
H
P
E
V
S
P
S
P
R
F
V
A
A
K
Site 38
T315
P
R
F
V
A
A
K
T
Q
T
N
Q
S
G
K
Site 39
T317
F
V
A
A
K
T
Q
T
N
Q
S
G
K
K
A
Site 40
S320
A
K
T
Q
T
N
Q
S
G
K
K
A
P
A
S
Site 41
T338
C
A
T
L
L
H
R
T
P
P
A
T
Q
T
Q
Site 42
T342
L
H
R
T
P
P
A
T
Q
T
Q
T
F
R
T
Site 43
T346
P
P
A
T
Q
T
Q
T
F
R
T
P
N
S
G
Site 44
T349
T
Q
T
Q
T
F
R
T
P
N
S
G
S
P
A
Site 45
S352
Q
T
F
R
T
P
N
S
G
S
P
A
S
K
A
Site 46
S354
F
R
T
P
N
S
G
S
P
A
S
K
A
T
A
Site 47
S357
P
N
S
G
S
P
A
S
K
A
T
A
A
E
S
Site 48
S367
T
A
A
E
S
A
F
S
R
R
V
E
G
K
A
Site 49
T381
A
Q
N
H
F
E
E
T
N
S
S
S
Q
N
S
Site 50
S383
N
H
F
E
E
T
N
S
S
S
Q
N
S
S
E
Site 51
S384
H
F
E
E
T
N
S
S
S
Q
N
S
S
E
P
Site 52
S385
F
E
E
T
N
S
S
S
Q
N
S
S
E
P
Y
Site 53
S388
T
N
S
S
S
Q
N
S
S
E
P
Y
T
C
G
Site 54
S389
N
S
S
S
Q
N
S
S
E
P
Y
T
C
G
A
Site 55
Y392
S
Q
N
S
S
E
P
Y
T
C
G
A
C
G
I
Site 56
T393
Q
N
S
S
E
P
Y
T
C
G
A
C
G
I
Q
Site 57
S413
N
L
L
E
H
M
Q
S
H
A
A
D
N
E
N
Site 58
S424
D
N
E
N
N
I
A
S
N
Q
S
R
S
P
P
Site 59
S429
I
A
S
N
Q
S
R
S
P
P
A
V
V
E
E
Site 60
S446
K
P
Q
A
Q
R
N
S
A
N
N
T
T
T
S
Site 61
T450
Q
R
N
S
A
N
N
T
T
T
S
G
L
T
P
Site 62
T456
N
T
T
T
S
G
L
T
P
N
S
M
I
P
E
Site 63
S459
T
S
G
L
T
P
N
S
M
I
P
E
K
E
R
Site 64
T498
E
F
L
K
L
A
Q
T
L
V
D
S
G
A
R
Site 65
Y530
L
K
H
L
P
R
M
Y
N
Q
V
K
V
K
V
Site 66
S555
G
I
G
V
T
C
H
S
Q
S
V
G
P
D
S
Site 67
S557
G
V
T
C
H
S
Q
S
V
G
P
D
S
C
Y
Site 68
S562
S
Q
S
V
G
P
D
S
C
Y
I
L
T
A
Y
Site 69
Y569
S
C
Y
I
L
T
A
Y
Q
A
E
G
N
H
I
Site 70
S578
A
E
G
N
H
I
K
S
Y
V
L
G
V
K
G
Site 71
Y579
E
G
N
H
I
K
S
Y
V
L
G
V
K
G
A
Site 72
S591
K
G
A
D
I
R
D
S
G
D
L
V
H
H
W
Site 73
Y615
M
S
E
I
R
T
V
Y
V
T
D
C
R
V
S
Site 74
T617
E
I
R
T
V
Y
V
T
D
C
R
V
S
T
S
Site 75
S622
Y
V
T
D
C
R
V
S
T
S
A
F
S
K
A
Site 76
T623
V
T
D
C
R
V
S
T
S
A
F
S
K
A
G
Site 77
S649
S
V
V
Q
S
V
L
S
K
R
T
L
Q
A
R
Site 78
S657
K
R
T
L
Q
A
R
S
M
H
E
V
I
E
L
Site 79
T681
S
T
G
L
A
K
E
T
F
G
S
L
E
E
T
Site 80
S684
L
A
K
E
T
F
G
S
L
E
E
T
S
P
P
Site 81
T688
T
F
G
S
L
E
E
T
S
P
P
P
C
W
N
Site 82
S689
F
G
S
L
E
E
T
S
P
P
P
C
W
N
S
Site 83
S696
S
P
P
P
C
W
N
S
V
T
D
S
L
L
L
Site 84
S700
C
W
N
S
V
T
D
S
L
L
L
V
H
E
R
Site 85
Y708
L
L
L
V
H
E
R
Y
E
Q
I
C
E
F
Y
Site 86
Y715
Y
E
Q
I
C
E
F
Y
S
R
A
K
K
M
N
Site 87
S716
E
Q
I
C
E
F
Y
S
R
A
K
K
M
N
L
Site 88
S726
K
K
M
N
L
I
Q
S
L
N
K
H
L
L
S
Site 89
S750
K
Q
A
V
I
E
L
S
N
E
S
Q
P
T
L
Site 90
T756
L
S
N
E
S
Q
P
T
L
Q
L
V
L
P
T
Site 91
T772
V
R
L
E
K
L
F
T
A
K
A
N
D
A
G
Site 92
T780
A
K
A
N
D
A
G
T
V
S
K
L
C
H
L
Site 93
S782
A
N
D
A
G
T
V
S
K
L
C
H
L
F
L
Site 94
Y820
K
L
R
P
V
P
P
Y
Q
H
E
E
I
I
G
Site 95
S839
L
I
N
E
V
K
E
S
W
A
E
E
A
D
F
Site 96
S855
P
A
A
K
K
P
R
S
A
A
V
E
N
P
A
Site 97
Y875
R
L
G
K
N
E
V
Y
D
Y
L
Q
E
P
L
Site 98
Y877
G
K
N
E
V
Y
D
Y
L
Q
E
P
L
F
Q
Site 99
T886
Q
E
P
L
F
Q
A
T
P
D
L
F
Q
Y
W
Site 100
Y892
A
T
P
D
L
F
Q
Y
W
S
C
V
T
Q
K
Site 101
S939
I
K
R
R
R
L
L
S
P
E
D
M
N
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation