KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ANKRD38
Full Name:
KN motif and ankyrin repeat domain-containing protein 4
Alias:
Ankyrin repeat domain 38; Ankyrin repeat domain-containing protein 38; ANR38; KIAA0172; KN motif and ankyrin repeat domains 4
Type:
Unknown function
Mass (Da):
107340
Number AA:
UniProt ID:
Q5T7N3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
T
D
A
K
D
Q
S
S
Q
G
D
E
E
K
D
Site 2
S22
E
E
K
D
P
P
K
S
H
P
Y
S
V
E
T
Site 3
S26
P
P
K
S
H
P
Y
S
V
E
T
P
Y
G
F
Site 4
T29
S
H
P
Y
S
V
E
T
P
Y
G
F
H
L
D
Site 5
Y42
L
D
L
D
F
L
K
Y
V
D
D
I
E
K
G
Site 6
T51
D
D
I
E
K
G
N
T
I
K
R
I
P
I
H
Site 7
T68
A
K
Q
A
K
F
S
T
L
P
R
N
F
S
L
Site 8
S74
S
T
L
P
R
N
F
S
L
P
D
S
G
A
R
Site 9
S78
R
N
F
S
L
P
D
S
G
A
R
P
P
A
A
Site 10
S92
A
P
P
L
Q
N
W
S
P
V
V
P
R
E
A
Site 11
S100
P
V
V
P
R
E
A
S
L
G
T
Q
E
Q
N
Site 12
S109
G
T
Q
E
Q
N
Q
S
P
P
L
G
N
A
P
Site 13
S119
L
G
N
A
P
Q
A
S
T
S
R
S
E
V
S
Site 14
T120
G
N
A
P
Q
A
S
T
S
R
S
E
V
S
Y
Site 15
S121
N
A
P
Q
A
S
T
S
R
S
E
V
S
Y
H
Site 16
S123
P
Q
A
S
T
S
R
S
E
V
S
Y
H
R
K
Site 17
S126
S
T
S
R
S
E
V
S
Y
H
R
K
A
L
L
Site 18
Y127
T
S
R
S
E
V
S
Y
H
R
K
A
L
L
A
Site 19
T151
E
P
E
D
A
E
L
T
F
G
S
G
R
P
Q
Site 20
S154
D
A
E
L
T
F
G
S
G
R
P
Q
L
L
R
Site 21
S163
R
P
Q
L
L
R
A
S
S
M
P
A
T
L
L
Site 22
S164
P
Q
L
L
R
A
S
S
M
P
A
T
L
L
H
Site 23
T168
R
A
S
S
M
P
A
T
L
L
H
S
R
A
S
Site 24
S175
T
L
L
H
S
R
A
S
E
E
P
G
L
S
L
Site 25
S181
A
S
E
E
P
G
L
S
L
G
P
P
A
P
P
Site 26
S198
P
P
L
Q
G
E
G
S
V
C
D
G
T
F
E
Site 27
T203
E
G
S
V
C
D
G
T
F
E
P
A
E
G
L
Site 28
S215
E
G
L
A
G
F
H
S
S
S
P
R
A
S
T
Site 29
S216
G
L
A
G
F
H
S
S
S
P
R
A
S
T
R
Site 30
S217
L
A
G
F
H
S
S
S
P
R
A
S
T
R
I
Site 31
S221
H
S
S
S
P
R
A
S
T
R
I
P
E
L
V
Site 32
T222
S
S
S
P
R
A
S
T
R
I
P
E
L
V
Q
Site 33
T278
R
E
A
E
V
L
F
T
P
G
S
P
T
P
S
Site 34
S281
E
V
L
F
T
P
G
S
P
T
P
S
P
P
P
Site 35
T283
L
F
T
P
G
S
P
T
P
S
P
P
P
L
P
Site 36
S285
T
P
G
S
P
T
P
S
P
P
P
L
P
S
P
Site 37
S291
P
S
P
P
P
L
P
S
P
I
P
E
N
E
L
Site 38
S308
E
E
I
E
L
N
I
S
E
I
P
P
P
P
P
Site 39
S322
P
V
E
V
D
M
R
S
I
G
I
R
V
T
E
Site 40
S331
G
I
R
V
T
E
E
S
L
G
L
A
R
V
D
Site 41
S341
L
A
R
V
D
P
G
S
I
S
S
L
K
Q
Q
Site 42
S344
V
D
P
G
S
I
S
S
L
K
Q
Q
V
S
A
Site 43
S350
S
S
L
K
Q
Q
V
S
A
L
E
G
E
L
S
Site 44
S357
S
A
L
E
G
E
L
S
G
R
T
E
E
L
A
Site 45
T390
R
I
R
E
L
E
F
T
V
A
Q
L
E
G
Q
Site 46
S427
H
G
L
L
T
R
E
S
C
D
K
G
I
E
V
Site 47
S439
I
E
V
N
L
L
G
S
M
E
S
E
S
W
G
Site 48
S442
N
L
L
G
S
M
E
S
E
S
W
G
H
R
G
Site 49
S444
L
G
S
M
E
S
E
S
W
G
H
R
G
E
E
Site 50
S467
G
H
K
Q
G
N
Q
S
P
A
E
R
V
L
L
Site 51
S478
R
V
L
L
P
Q
L
S
L
P
Q
G
P
E
Q
Site 52
T488
Q
G
P
E
Q
V
L
T
S
S
V
H
S
F
L
Site 53
S489
G
P
E
Q
V
L
T
S
S
V
H
S
F
L
S
Site 54
S490
P
E
Q
V
L
T
S
S
V
H
S
F
L
S
T
Site 55
S496
S
S
V
H
S
F
L
S
T
E
L
R
I
E
E
Site 56
T497
S
V
H
S
F
L
S
T
E
L
R
I
E
E
A
Site 57
T506
L
R
I
E
E
A
G
T
E
Q
E
G
G
P
Q
Site 58
S526
A
G
G
F
L
W
G
S
D
R
K
T
P
P
A
Site 59
T530
L
W
G
S
D
R
K
T
P
P
A
G
R
E
E
Site 60
T538
P
P
A
G
R
E
E
T
S
S
N
L
P
G
K
Site 61
S540
A
G
R
E
E
T
S
S
N
L
P
G
K
E
H
Site 62
S553
E
H
P
G
R
P
P
S
S
P
T
D
A
T
I
Site 63
S554
H
P
G
R
P
P
S
S
P
T
D
A
T
I
G
Site 64
T556
G
R
P
P
S
S
P
T
D
A
T
I
G
Q
Y
Site 65
Y563
T
D
A
T
I
G
Q
Y
V
K
K
I
Q
E
L
Site 66
Y582
W
N
C
L
E
H
G
Y
P
E
L
A
S
A
I
Site 67
S587
H
G
Y
P
E
L
A
S
A
I
K
Q
P
A
S
Site 68
S594
S
A
I
K
Q
P
A
S
K
L
S
S
I
Q
S
Site 69
S597
K
Q
P
A
S
K
L
S
S
I
Q
S
Q
L
L
Site 70
S598
Q
P
A
S
K
L
S
S
I
Q
S
Q
L
L
S
Site 71
S601
S
K
L
S
S
I
Q
S
Q
L
L
S
S
L
N
Site 72
S615
N
L
L
L
S
A
Y
S
A
Q
A
H
P
P
K
Site 73
S627
P
P
K
E
P
P
A
S
S
S
S
P
P
V
E
Site 74
S628
P
K
E
P
P
A
S
S
S
S
P
P
V
E
I
Site 75
S629
K
E
P
P
A
S
S
S
S
P
P
V
E
I
S
Site 76
S630
E
P
P
A
S
S
S
S
P
P
V
E
I
S
P
Site 77
S636
S
S
P
P
V
E
I
S
P
S
T
S
L
K
S
Site 78
S638
P
P
V
E
I
S
P
S
T
S
L
K
S
I
M
Site 79
T639
P
V
E
I
S
P
S
T
S
L
K
S
I
M
K
Site 80
S640
V
E
I
S
P
S
T
S
L
K
S
I
M
K
K
Site 81
S643
S
P
S
T
S
L
K
S
I
M
K
K
K
D
Y
Site 82
Y650
S
I
M
K
K
K
D
Y
G
F
R
A
G
G
N
Site 83
Y672
F
V
G
V
N
G
G
Y
E
T
T
S
S
E
E
Site 84
S676
N
G
G
Y
E
T
T
S
S
E
E
T
S
G
E
Site 85
S677
G
G
Y
E
T
T
S
S
E
E
T
S
G
E
D
Site 86
S681
T
T
S
S
E
E
T
S
G
E
D
S
T
P
E
Site 87
S685
E
E
T
S
G
E
D
S
T
P
E
D
L
S
D
Site 88
T686
E
T
S
G
E
D
S
T
P
E
D
L
S
D
S
Site 89
S691
D
S
T
P
E
D
L
S
D
S
E
A
E
K
K
Site 90
S693
T
P
E
D
L
S
D
S
E
A
E
K
K
C
D
Site 91
S740
P
G
E
E
V
P
H
S
K
A
E
R
Y
K
P
Site 92
S748
K
A
E
R
Y
K
P
S
E
E
F
L
N
A
C
Site 93
S759
L
N
A
C
R
A
L
S
Q
H
L
P
E
T
G
Site 94
T768
H
L
P
E
T
G
T
T
T
D
Q
L
L
R
Q
Site 95
S776
T
D
Q
L
L
R
Q
S
L
N
T
I
S
Q
E
Site 96
T779
L
L
R
Q
S
L
N
T
I
S
Q
E
W
F
R
Site 97
S781
R
Q
S
L
N
T
I
S
Q
E
W
F
R
V
S
Site 98
S788
S
Q
E
W
F
R
V
S
S
R
K
S
S
S
P
Site 99
S789
Q
E
W
F
R
V
S
S
R
K
S
S
S
P
A
Site 100
S792
F
R
V
S
S
R
K
S
S
S
P
A
V
V
A
Site 101
S793
R
V
S
S
R
K
S
S
S
P
A
V
V
A
S
Site 102
S794
V
S
S
R
K
S
S
S
P
A
V
V
A
S
Y
Site 103
S809
L
H
E
V
Q
P
H
S
P
H
F
L
K
L
L
Site 104
Y830
N
G
N
T
A
L
H
Y
S
V
S
H
S
N
F
Site 105
S831
G
N
T
A
L
H
Y
S
V
S
H
S
N
F
S
Site 106
S957
A
H
P
A
C
D
S
S
L
T
D
K
A
G
R
Site 107
S968
K
A
G
R
T
A
L
S
I
A
L
K
S
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation