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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPRC6A
Full Name:
G-protein coupled receptor family C group 6 member A
Alias:
BA86F4.3; G protein-coupled receptor, family C, group 6, member A; GPC6A; GPCR33; G-protein coupled receptor 33
Type:
Mass (Da):
104750
Number AA:
UniProt ID:
Q5T6X5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T23
A
T
S
Q
P
C
Q
T
P
D
D
F
V
A
A
Site 2
S50
A
I
H
E
K
M
L
S
S
E
D
S
P
R
R
Site 3
S51
I
H
E
K
M
L
S
S
E
D
S
P
R
R
P
Site 4
S54
K
M
L
S
S
E
D
S
P
R
R
P
Q
I
Q
Site 5
Y100
V
K
L
G
Y
E
I
Y
D
T
C
T
E
V
T
Site 6
T107
Y
D
T
C
T
E
V
T
V
A
M
A
A
T
L
Site 7
S118
A
A
T
L
R
F
L
S
K
F
N
C
S
R
E
Site 8
Y133
T
V
E
F
K
C
D
Y
S
S
Y
M
P
R
V
Site 9
Y136
F
K
C
D
Y
S
S
Y
M
P
R
V
K
A
V
Site 10
S171
M
P
Q
V
G
Y
E
S
T
A
E
I
L
S
D
Site 11
S177
E
S
T
A
E
I
L
S
D
K
I
R
F
P
S
Site 12
S184
S
D
K
I
R
F
P
S
F
L
R
T
V
P
S
Site 13
T188
R
F
P
S
F
L
R
T
V
P
S
D
F
H
Q
Site 14
S191
S
F
L
R
T
V
P
S
D
F
H
Q
I
K
A
Site 15
Y220
I
I
T
T
D
D
D
Y
G
R
L
A
L
N
T
Site 16
T253
P
A
F
L
S
D
N
T
I
E
V
R
I
N
R
Site 17
T261
I
E
V
R
I
N
R
T
L
K
K
I
I
L
E
Site 18
T312
W
S
T
A
T
K
I
T
T
I
P
N
V
K
K
Site 19
T313
S
T
A
T
K
I
T
T
I
P
N
V
K
K
I
Site 20
S334
A
F
R
R
G
N
I
S
S
F
H
S
F
L
Q
Site 21
S335
F
R
R
G
N
I
S
S
F
H
S
F
L
Q
N
Site 22
S338
G
N
I
S
S
F
H
S
F
L
Q
N
L
H
L
Site 23
S348
Q
N
L
H
L
L
P
S
D
S
H
K
L
L
H
Site 24
S350
L
H
L
L
P
S
D
S
H
K
L
L
H
E
Y
Site 25
Y357
S
H
K
L
L
H
E
Y
A
M
H
L
S
A
C
Site 26
Y366
M
H
L
S
A
C
A
Y
V
K
D
T
D
L
S
Site 27
Y406
R
N
D
F
L
W
D
Y
A
E
P
G
L
I
H
Site 28
T454
L
G
V
L
K
N
V
T
F
T
D
G
W
N
S
Site 29
Y474
H
G
D
L
N
T
G
Y
D
V
V
L
W
K
E
Site 30
T487
K
E
I
N
G
H
M
T
V
T
K
M
A
E
Y
Site 31
S520
R
N
L
K
Q
I
Q
S
K
C
S
K
E
C
S
Site 32
S523
K
Q
I
Q
S
K
C
S
K
E
C
S
P
G
Q
Site 33
S527
S
K
C
S
K
E
C
S
P
G
Q
M
K
K
T
Site 34
T534
S
P
G
Q
M
K
K
T
T
R
S
Q
H
I
C
Site 35
Y586
C
F
E
K
E
V
E
Y
L
N
W
N
D
S
L
Site 36
T621
I
F
T
R
N
L
N
T
P
V
V
K
S
S
G
Site 37
Y775
I
F
A
F
K
G
K
Y
E
N
Y
N
E
A
K
Site 38
Y778
F
K
G
K
Y
E
N
Y
N
E
A
K
F
I
T
Site 39
Y856
F
L
K
M
I
Y
S
Y
S
S
H
S
V
S
S
Site 40
S857
L
K
M
I
Y
S
Y
S
S
H
S
V
S
S
I
Site 41
S858
K
M
I
Y
S
Y
S
S
H
S
V
S
S
I
A
Site 42
S862
S
Y
S
S
H
S
V
S
S
I
A
L
S
P
A
Site 43
S863
Y
S
S
H
S
V
S
S
I
A
L
S
P
A
S
Site 44
S875
P
A
S
L
D
S
M
S
G
N
V
T
M
T
N
Site 45
T879
D
S
M
S
G
N
V
T
M
T
N
P
S
S
S
Site 46
T881
M
S
G
N
V
T
M
T
N
P
S
S
S
G
K
Site 47
S884
N
V
T
M
T
N
P
S
S
S
G
K
S
A
T
Site 48
S885
V
T
M
T
N
P
S
S
S
G
K
S
A
T
W
Site 49
S886
T
M
T
N
P
S
S
S
G
K
S
A
T
W
Q
Site 50
S889
N
P
S
S
S
G
K
S
A
T
W
Q
K
S
K
Site 51
T891
S
S
S
G
K
S
A
T
W
Q
K
S
K
D
L
Site 52
S895
K
S
A
T
W
Q
K
S
K
D
L
Q
A
Q
A
Site 53
S913
I
C
R
E
N
A
T
S
V
S
K
T
L
P
R
Site 54
T917
N
A
T
S
V
S
K
T
L
P
R
K
R
M
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation