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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR40A
Full Name:
DDB1- and CUL4-associated factor 12
Alias:
centrosome related protein; Centrosome-related protein tcc52; KIAA1892; Tcc52; Wd repeat domain 40a; Wd repeat-containing protein 40a; Wd40a; Wdr40a
Type:
Mass (Da):
50517
Number AA:
453
UniProt ID:
Q5T6F0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
R
K
R
K
A
P
A
S
P
G
A
G
S
D
A
Site 2
S20
P
A
S
P
G
A
G
S
D
A
Q
G
P
Q
F
Site 3
S32
P
Q
F
G
W
D
H
S
L
H
K
R
K
R
L
Site 4
S45
R
L
P
P
V
K
R
S
L
V
Y
Y
L
K
N
Site 5
Y49
V
K
R
S
L
V
Y
Y
L
K
N
R
E
V
R
Site 6
T61
E
V
R
L
Q
N
E
T
S
Y
S
R
V
L
H
Site 7
S62
V
R
L
Q
N
E
T
S
Y
S
R
V
L
H
G
Site 8
Y63
R
L
Q
N
E
T
S
Y
S
R
V
L
H
G
Y
Site 9
S64
L
Q
N
E
T
S
Y
S
R
V
L
H
G
Y
A
Site 10
Y70
Y
S
R
V
L
H
G
Y
A
A
Q
Q
L
P
S
Site 11
S77
Y
A
A
Q
Q
L
P
S
L
L
K
E
R
E
F
Site 12
T88
E
R
E
F
H
L
G
T
L
N
K
V
F
A
S
Site 13
S151
H
A
I
E
L
N
P
S
R
T
L
L
A
T
G
Site 14
T153
I
E
L
N
P
S
R
T
L
L
A
T
G
G
D
Site 15
T157
P
S
R
T
L
L
A
T
G
G
D
N
P
N
S
Site 16
S164
T
G
G
D
N
P
N
S
L
A
I
Y
R
L
P
Site 17
Y168
N
P
N
S
L
A
I
Y
R
L
P
T
L
D
P
Site 18
S200
I
S
D
T
M
A
V
S
G
S
R
D
G
S
M
Site 19
S202
D
T
M
A
V
S
G
S
R
D
G
S
M
G
L
Site 20
S206
V
S
G
S
R
D
G
S
M
G
L
W
E
V
T
Site 21
T218
E
V
T
D
D
V
L
T
K
S
D
A
R
H
N
Site 22
S220
T
D
D
V
L
T
K
S
D
A
R
H
N
V
S
Site 23
S227
S
D
A
R
H
N
V
S
R
V
P
V
Y
A
H
Site 24
Y232
N
V
S
R
V
P
V
Y
A
H
I
T
H
K
A
Site 25
T248
K
D
I
P
K
E
D
T
N
P
D
N
C
K
V
Site 26
S271
N
K
E
L
G
A
V
S
L
D
G
Y
F
H
L
Site 27
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Site 28
T284
H
L
W
K
A
E
N
T
L
S
K
L
L
S
T
Site 29
S286
W
K
A
E
N
T
L
S
K
L
L
S
T
K
L
Site 30
S290
N
T
L
S
K
L
L
S
T
K
L
P
Y
C
R
Site 31
Y304
R
E
N
V
C
L
A
Y
G
S
E
W
S
V
Y
Site 32
S309
L
A
Y
G
S
E
W
S
V
Y
A
V
G
S
Q
Site 33
Y311
Y
G
S
E
W
S
V
Y
A
V
G
S
Q
A
H
Site 34
S320
V
G
S
Q
A
H
V
S
F
L
D
P
R
Q
P
Site 35
S328
F
L
D
P
R
Q
P
S
Y
N
V
K
S
V
C
Site 36
Y329
L
D
P
R
Q
P
S
Y
N
V
K
S
V
C
S
Site 37
S333
Q
P
S
Y
N
V
K
S
V
C
S
R
E
R
G
Site 38
S336
Y
N
V
K
S
V
C
S
R
E
R
G
S
G
I
Site 39
S341
V
C
S
R
E
R
G
S
G
I
R
S
V
S
F
Site 40
S345
E
R
G
S
G
I
R
S
V
S
F
Y
E
H
I
Site 41
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Site 42
Y365
G
Q
G
S
L
L
F
Y
D
I
R
A
Q
R
F
Site 43
S378
R
F
L
E
E
R
L
S
A
C
Y
G
S
K
P
Site 44
Y381
E
E
R
L
S
A
C
Y
G
S
K
P
R
L
A
Site 45
S383
R
L
S
A
C
Y
G
S
K
P
R
L
A
G
E
Site 46
T395
A
G
E
N
L
K
L
T
T
G
K
G
W
L
N
Site 47
Y426
N
A
V
Y
T
H
C
Y
D
S
S
G
T
K
L
Site 48
Y448
P
S
G
L
H
G
N
Y
A
G
L
W
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation