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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SKT
Full Name:
Sickle tail protein homolog
Alias:
DKFZP761L0424; KIAA1217; Sickle tail; Sickle tail protein
Type:
Unknown function
Mass (Da):
214116
Number AA:
1943
UniProt ID:
Q5T5P2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0048706
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
K
G
N
L
H
V
T
S
P
E
D
A
E
C
R
Site 2
T43
E
D
A
E
C
R
R
T
K
E
R
L
S
N
G
Site 3
S48
R
R
T
K
E
R
L
S
N
G
N
S
R
G
S
Site 4
S52
E
R
L
S
N
G
N
S
R
G
S
V
S
K
S
Site 5
S55
S
N
G
N
S
R
G
S
V
S
K
S
S
R
N
Site 6
S57
G
N
S
R
G
S
V
S
K
S
S
R
N
I
P
Site 7
S59
S
R
G
S
V
S
K
S
S
R
N
I
P
R
R
Site 8
T68
R
N
I
P
R
R
H
T
L
G
G
P
R
S
S
Site 9
S74
H
T
L
G
G
P
R
S
S
K
E
I
L
G
M
Site 10
S75
T
L
G
G
P
R
S
S
K
E
I
L
G
M
Q
Site 11
S84
E
I
L
G
M
Q
T
S
E
M
D
R
K
R
E
Site 12
Y101
L
E
H
L
K
Q
K
Y
P
H
H
A
S
A
I
Site 13
T119
Q
E
R
L
R
D
Q
T
R
S
P
K
L
S
H
Site 14
S121
R
L
R
D
Q
T
R
S
P
K
L
S
H
S
P
Site 15
S125
Q
T
R
S
P
K
L
S
H
S
P
Q
P
P
S
Site 16
S127
R
S
P
K
L
S
H
S
P
Q
P
P
S
L
G
Site 17
S132
S
H
S
P
Q
P
P
S
L
G
D
P
V
E
H
Site 18
S141
G
D
P
V
E
H
L
S
E
T
S
A
D
S
L
Site 19
T143
P
V
E
H
L
S
E
T
S
A
D
S
L
E
A
Site 20
S147
L
S
E
T
S
A
D
S
L
E
A
M
S
E
G
Site 21
T158
M
S
E
G
D
A
P
T
P
F
S
R
G
S
R
Site 22
S161
G
D
A
P
T
P
F
S
R
G
S
R
T
R
A
Site 23
S164
P
T
P
F
S
R
G
S
R
T
R
A
S
L
P
Site 24
T166
P
F
S
R
G
S
R
T
R
A
S
L
P
V
V
Site 25
S169
R
G
S
R
T
R
A
S
L
P
V
V
R
S
T
Site 26
S175
A
S
L
P
V
V
R
S
T
N
Q
T
K
E
R
Site 27
T176
S
L
P
V
V
R
S
T
N
Q
T
K
E
R
S
Site 28
T179
V
V
R
S
T
N
Q
T
K
E
R
S
L
G
V
Site 29
Y188
E
R
S
L
G
V
L
Y
L
Q
Y
G
D
E
T
Site 30
Y191
L
G
V
L
Y
L
Q
Y
G
D
E
T
K
Q
L
Site 31
T223
S
A
F
P
Q
Q
L
T
M
K
M
L
E
S
P
Site 32
Y235
E
S
P
S
V
A
I
Y
I
K
D
E
S
R
N
Site 33
Y244
K
D
E
S
R
N
V
Y
Y
E
L
N
D
V
R
Site 34
Y245
D
E
S
R
N
V
Y
Y
E
L
N
D
V
R
N
Site 35
S257
V
R
N
I
Q
D
R
S
L
L
K
V
Y
N
K
Site 36
T273
P
A
H
A
F
N
H
T
P
K
T
M
N
G
D
Site 37
Y289
R
M
Q
R
E
L
V
Y
A
R
G
D
G
P
G
Site 38
S302
P
G
A
P
R
P
G
S
T
A
H
P
P
H
A
Site 39
S313
P
P
H
A
I
P
N
S
P
P
S
T
P
V
P
Site 40
S316
A
I
P
N
S
P
P
S
T
P
V
P
H
S
M
Site 41
T317
I
P
N
S
P
P
S
T
P
V
P
H
S
M
P
Site 42
S322
P
S
T
P
V
P
H
S
M
P
P
S
P
S
R
Site 43
S326
V
P
H
S
M
P
P
S
P
S
R
I
P
Y
G
Site 44
S328
H
S
M
P
P
S
P
S
R
I
P
Y
G
G
T
Site 45
Y332
P
S
P
S
R
I
P
Y
G
G
T
R
S
M
V
Site 46
T345
M
V
V
P
G
N
A
T
I
P
R
D
R
I
S
Site 47
S352
T
I
P
R
D
R
I
S
S
L
P
V
S
R
P
Site 48
S353
I
P
R
D
R
I
S
S
L
P
V
S
R
P
I
Site 49
S357
R
I
S
S
L
P
V
S
R
P
I
S
P
S
P
Site 50
S361
L
P
V
S
R
P
I
S
P
S
P
S
A
I
L
Site 51
S363
V
S
R
P
I
S
P
S
P
S
A
I
L
E
R
Site 52
S365
R
P
I
S
P
S
P
S
A
I
L
E
R
R
D
Site 53
Y387
S
G
K
N
I
A
M
Y
R
N
E
G
F
Y
A
Site 54
Y393
M
Y
R
N
E
G
F
Y
A
D
P
Y
L
Y
H
Site 55
Y397
E
G
F
Y
A
D
P
Y
L
Y
H
E
G
R
M
Site 56
Y399
F
Y
A
D
P
Y
L
Y
H
E
G
R
M
S
I
Site 57
S405
L
Y
H
E
G
R
M
S
I
A
S
S
H
G
G
Site 58
S408
E
G
R
M
S
I
A
S
S
H
G
G
H
P
L
Site 59
S409
G
R
M
S
I
A
S
S
H
G
G
H
P
L
D
Site 60
Y424
V
P
D
H
I
I
A
Y
H
R
T
A
I
R
S
Site 61
S433
R
T
A
I
R
S
A
S
A
Y
C
N
P
S
M
Site 62
Y435
A
I
R
S
A
S
A
Y
C
N
P
S
M
Q
A
Site 63
S449
A
E
M
H
M
E
Q
S
L
Y
R
Q
K
S
R
Site 64
Y451
M
H
M
E
Q
S
L
Y
R
Q
K
S
R
K
Y
Site 65
S455
Q
S
L
Y
R
Q
K
S
R
K
Y
P
D
S
H
Site 66
Y458
Y
R
Q
K
S
R
K
Y
P
D
S
H
L
P
T
Site 67
S461
K
S
R
K
Y
P
D
S
H
L
P
T
L
G
S
Site 68
T465
Y
P
D
S
H
L
P
T
L
G
S
K
T
P
P
Site 69
S468
S
H
L
P
T
L
G
S
K
T
P
P
A
S
P
Site 70
T470
L
P
T
L
G
S
K
T
P
P
A
S
P
H
R
Site 71
S474
G
S
K
T
P
P
A
S
P
H
R
V
S
D
L
Site 72
S479
P
A
S
P
H
R
V
S
D
L
R
M
I
D
M
Site 73
Y490
M
I
D
M
H
A
H
Y
N
A
H
G
P
P
H
Site 74
T498
N
A
H
G
P
P
H
T
M
Q
P
D
R
A
S
Site 75
S505
T
M
Q
P
D
R
A
S
P
S
R
Q
A
F
K
Site 76
Y520
K
E
P
G
T
L
V
Y
I
E
K
P
R
S
A
Site 77
S526
V
Y
I
E
K
P
R
S
A
A
G
L
S
S
L
Site 78
S531
P
R
S
A
A
G
L
S
S
L
V
D
L
G
P
Site 79
Y548
M
E
K
Q
V
F
A
Y
S
T
A
T
I
P
K
Site 80
T550
K
Q
V
F
A
Y
S
T
A
T
I
P
K
D
R
Site 81
T552
V
F
A
Y
S
T
A
T
I
P
K
D
R
E
T
Site 82
T559
T
I
P
K
D
R
E
T
R
E
R
M
Q
A
M
Site 83
S588
L
F
K
G
P
I
T
S
Y
S
K
D
A
S
S
Site 84
S590
K
G
P
I
T
S
Y
S
K
D
A
S
S
E
K
Site 85
S594
T
S
Y
S
K
D
A
S
S
E
K
M
M
K
T
Site 86
S595
S
Y
S
K
D
A
S
S
E
K
M
M
K
T
T
Site 87
T601
S
S
E
K
M
M
K
T
T
A
N
R
N
H
T
Site 88
T608
T
T
A
N
R
N
H
T
D
S
A
G
T
P
H
Site 89
S610
A
N
R
N
H
T
D
S
A
G
T
P
H
V
S
Site 90
T613
N
H
T
D
S
A
G
T
P
H
V
S
G
G
K
Site 91
S617
S
A
G
T
P
H
V
S
G
G
K
M
L
S
A
Site 92
S627
K
M
L
S
A
L
E
S
T
V
P
P
S
Q
P
Site 93
T628
M
L
S
A
L
E
S
T
V
P
P
S
Q
P
P
Site 94
S632
L
E
S
T
V
P
P
S
Q
P
P
P
V
G
T
Site 95
S652
S
L
L
E
M
R
R
S
V
A
E
L
R
L
Q
Site 96
S686
K
K
A
E
L
E
I
S
G
K
V
M
E
T
M
Site 97
Y714
V
E
Q
E
R
Q
K
Y
L
H
E
E
E
K
I
Site 98
S739
V
E
D
L
K
K
D
S
T
A
A
S
R
L
V
Site 99
T740
E
D
L
K
K
D
S
T
A
A
S
R
L
V
T
Site 100
S743
K
K
D
S
T
A
A
S
R
L
V
T
L
K
D
Site 101
T747
T
A
A
S
R
L
V
T
L
K
D
V
E
D
G
Site 102
T767
Q
V
G
E
A
V
A
T
L
K
G
E
F
P
T
Site 103
S802
E
E
P
H
K
L
D
S
L
L
K
R
V
R
S
Site 104
S809
S
L
L
K
R
V
R
S
M
T
D
V
L
T
M
Site 105
T811
L
K
R
V
R
S
M
T
D
V
L
T
M
L
R
Site 106
T815
R
S
M
T
D
V
L
T
M
L
R
R
H
V
T
Site 107
T822
T
M
L
R
R
H
V
T
D
G
L
L
K
G
T
Site 108
Y837
D
A
A
Q
A
A
Q
Y
M
A
M
E
K
A
T
Site 109
S851
T
A
A
E
V
L
K
S
Q
E
E
A
A
H
T
Site 110
T858
S
Q
E
E
A
A
H
T
S
G
Q
P
F
H
S
Site 111
S865
T
S
G
Q
P
F
H
S
T
G
A
P
G
D
A
Site 112
T866
S
G
Q
P
F
H
S
T
G
A
P
G
D
A
K
Site 113
S874
G
A
P
G
D
A
K
S
E
V
V
P
L
S
G
Site 114
S890
M
V
R
H
A
Q
S
S
P
V
V
I
Q
P
S
Site 115
S915
Q
N
L
P
H
V
A
S
S
P
A
V
P
Q
E
Site 116
S916
N
L
P
H
V
A
S
S
P
A
V
P
Q
E
A
Site 117
T926
V
P
Q
E
A
T
S
T
L
Q
M
S
Q
A
P
Site 118
S930
A
T
S
T
L
Q
M
S
Q
A
P
Q
S
P
Q
Site 119
S935
Q
M
S
Q
A
P
Q
S
P
Q
I
P
M
N
G
Site 120
S947
M
N
G
S
A
M
Q
S
L
F
I
E
E
I
H
Site 121
S955
L
F
I
E
E
I
H
S
V
S
A
K
N
R
A
Site 122
S964
S
A
K
N
R
A
V
S
I
E
K
A
E
K
K
Site 123
Y982
K
R
Q
N
L
D
H
Y
N
G
K
E
F
E
K
Site 124
S1001
A
Q
A
N
I
M
K
S
I
P
N
L
E
M
P
Site 125
T1011
N
L
E
M
P
P
A
T
G
P
L
P
R
G
D
Site 126
S1027
P
V
D
K
V
E
L
S
E
D
S
P
N
S
E
Site 127
S1030
K
V
E
L
S
E
D
S
P
N
S
E
Q
D
L
Site 128
S1033
L
S
E
D
S
P
N
S
E
Q
D
L
E
K
L
Site 129
S1044
L
E
K
L
G
G
K
S
P
P
P
P
P
P
P
Site 130
S1055
P
P
P
P
P
R
R
S
Y
L
P
G
S
G
L
Site 131
Y1056
P
P
P
P
R
R
S
Y
L
P
G
S
G
L
T
Site 132
S1060
R
R
S
Y
L
P
G
S
G
L
T
T
T
R
S
Site 133
T1063
Y
L
P
G
S
G
L
T
T
T
R
S
G
D
V
Site 134
T1064
L
P
G
S
G
L
T
T
T
R
S
G
D
V
V
Site 135
T1065
P
G
S
G
L
T
T
T
R
S
G
D
V
V
Y
Site 136
S1067
S
G
L
T
T
T
R
S
G
D
V
V
Y
T
G
Site 137
Y1072
T
R
S
G
D
V
V
Y
T
G
R
K
E
N
I
Site 138
T1073
R
S
G
D
V
V
Y
T
G
R
K
E
N
I
T
Site 139
T1080
T
G
R
K
E
N
I
T
A
K
A
S
S
E
D
Site 140
S1085
N
I
T
A
K
A
S
S
E
D
A
G
P
S
P
Site 141
S1091
S
S
E
D
A
G
P
S
P
Q
T
R
A
T
K
Site 142
T1097
P
S
P
Q
T
R
A
T
K
Y
P
A
E
E
P
Site 143
Y1099
P
Q
T
R
A
T
K
Y
P
A
E
E
P
A
S
Site 144
S1106
Y
P
A
E
E
P
A
S
A
W
T
P
S
P
P
Site 145
T1109
E
E
P
A
S
A
W
T
P
S
P
P
P
V
T
Site 146
S1111
P
A
S
A
W
T
P
S
P
P
P
V
T
T
S
Site 147
T1116
T
P
S
P
P
P
V
T
T
S
S
S
K
D
E
Site 148
S1118
S
P
P
P
V
T
T
S
S
S
K
D
E
E
E
Site 149
S1119
P
P
P
V
T
T
S
S
S
K
D
E
E
E
E
Site 150
S1150
C
S
F
M
D
V
N
S
N
S
H
A
E
P
S
Site 151
S1152
F
M
D
V
N
S
N
S
H
A
E
P
S
R
A
Site 152
S1157
S
N
S
H
A
E
P
S
R
A
D
S
H
V
K
Site 153
S1161
A
E
P
S
R
A
D
S
H
V
K
D
T
R
S
Site 154
S1168
S
H
V
K
D
T
R
S
G
A
T
V
P
P
K
Site 155
T1171
K
D
T
R
S
G
A
T
V
P
P
K
E
K
K
Site 156
S1190
F
H
E
D
V
R
K
S
D
V
E
Y
E
N
G
Site 157
Y1194
V
R
K
S
D
V
E
Y
E
N
G
P
Q
M
E
Site 158
S1213
T
T
G
A
V
R
P
S
D
P
P
K
W
E
R
Site 159
S1225
W
E
R
G
M
E
N
S
I
S
D
A
S
R
T
Site 160
S1227
R
G
M
E
N
S
I
S
D
A
S
R
T
S
E
Site 161
S1230
E
N
S
I
S
D
A
S
R
T
S
E
Y
K
T
Site 162
S1233
I
S
D
A
S
R
T
S
E
Y
K
T
E
I
I
Site 163
Y1235
D
A
S
R
T
S
E
Y
K
T
E
I
I
M
K
Site 164
T1237
S
R
T
S
E
Y
K
T
E
I
I
M
K
E
N
Site 165
S1247
I
M
K
E
N
S
I
S
N
M
S
L
L
R
D
Site 166
S1250
E
N
S
I
S
N
M
S
L
L
R
D
S
R
N
Site 167
S1255
N
M
S
L
L
R
D
S
R
N
Y
S
Q
E
T
Site 168
Y1258
L
L
R
D
S
R
N
Y
S
Q
E
T
V
P
K
Site 169
S1259
L
R
D
S
R
N
Y
S
Q
E
T
V
P
K
A
Site 170
T1262
S
R
N
Y
S
Q
E
T
V
P
K
A
S
F
G
Site 171
S1267
Q
E
T
V
P
K
A
S
F
G
F
S
G
I
S
Site 172
S1271
P
K
A
S
F
G
F
S
G
I
S
P
L
E
D
Site 173
S1274
S
F
G
F
S
G
I
S
P
L
E
D
E
I
N
Site 174
Y1291
S
K
I
S
G
L
Q
Y
S
I
P
D
T
E
N
Site 175
S1292
K
I
S
G
L
Q
Y
S
I
P
D
T
E
N
Q
Site 176
T1296
L
Q
Y
S
I
P
D
T
E
N
Q
T
L
N
Y
Site 177
T1314
K
E
M
E
K
Q
N
T
D
K
C
H
V
S
S
Site 178
S1321
T
D
K
C
H
V
S
S
H
T
R
L
T
E
S
Site 179
T1326
V
S
S
H
T
R
L
T
E
S
S
V
H
D
F
Site 180
S1329
H
T
R
L
T
E
S
S
V
H
D
F
K
T
E
Site 181
T1335
S
S
V
H
D
F
K
T
E
D
Q
E
V
I
T
Site 182
S1368
N
P
N
E
D
G
E
S
S
S
S
S
P
T
E
Site 183
S1369
P
N
E
D
G
E
S
S
S
S
S
P
T
E
E
Site 184
S1370
N
E
D
G
E
S
S
S
S
S
P
T
E
E
N
Site 185
S1371
E
D
G
E
S
S
S
S
S
P
T
E
E
N
A
Site 186
S1372
D
G
E
S
S
S
S
S
P
T
E
E
N
A
A
Site 187
T1374
E
S
S
S
S
S
P
T
E
E
N
A
A
T
D
Site 188
T1380
P
T
E
E
N
A
A
T
D
N
I
A
F
M
I
Site 189
S1405
G
E
V
H
D
I
V
S
Q
K
G
E
D
I
Q
Site 190
T1413
Q
K
G
E
D
I
Q
T
V
N
I
D
A
R
K
Site 191
T1423
I
D
A
R
K
E
M
T
P
R
Q
E
G
T
D
Site 192
S1455
D
E
P
M
D
I
R
S
A
Y
K
R
L
S
T
Site 193
Y1457
P
M
D
I
R
S
A
Y
K
R
L
S
T
I
F
Site 194
S1461
R
S
A
Y
K
R
L
S
T
I
F
E
E
C
D
Site 195
T1462
S
A
Y
K
R
L
S
T
I
F
E
E
C
D
E
Site 196
S1491
E
E
E
E
N
G
D
S
V
V
Q
N
N
N
T
Site 197
S1521
G
Q
Q
V
E
T
K
S
Q
P
H
S
L
A
T
Site 198
S1525
E
T
K
S
Q
P
H
S
L
A
T
E
T
R
N
Site 199
T1528
S
Q
P
H
S
L
A
T
E
T
R
N
P
G
G
Site 200
T1530
P
H
S
L
A
T
E
T
R
N
P
G
G
Q
E
Site 201
T1541
G
G
Q
E
M
N
R
T
E
L
N
K
F
S
H
Site 202
S1547
R
T
E
L
N
K
F
S
H
V
D
S
P
N
S
Site 203
S1551
N
K
F
S
H
V
D
S
P
N
S
E
C
K
G
Site 204
S1554
S
H
V
D
S
P
N
S
E
C
K
G
E
D
A
Site 205
T1562
E
C
K
G
E
D
A
T
D
D
Q
F
E
S
P
Site 206
S1568
A
T
D
D
Q
F
E
S
P
K
K
K
F
K
F
Site 207
T1591
A
L
T
Q
A
I
R
T
G
T
K
T
G
K
K
Site 208
T1593
T
Q
A
I
R
T
G
T
K
T
G
K
K
T
L
Site 209
T1595
A
I
R
T
G
T
K
T
G
K
K
T
L
Q
V
Site 210
T1599
G
T
K
T
G
K
K
T
L
Q
V
V
V
Y
E
Site 211
Y1605
K
T
L
Q
V
V
V
Y
E
E
E
E
E
D
G
Site 212
T1613
E
E
E
E
E
D
G
T
L
K
Q
H
K
E
A
Site 213
S1628
K
R
F
E
I
A
R
S
Q
P
E
D
T
P
E
Site 214
T1633
A
R
S
Q
P
E
D
T
P
E
N
T
V
R
R
Site 215
T1637
P
E
D
T
P
E
N
T
V
R
R
Q
E
Q
P
Site 216
S1645
V
R
R
Q
E
Q
P
S
I
E
S
T
S
P
I
Site 217
S1648
Q
E
Q
P
S
I
E
S
T
S
P
I
S
R
T
Site 218
T1649
E
Q
P
S
I
E
S
T
S
P
I
S
R
T
D
Site 219
S1650
Q
P
S
I
E
S
T
S
P
I
S
R
T
D
E
Site 220
T1662
T
D
E
I
R
K
N
T
Y
R
T
L
D
S
L
Site 221
Y1663
D
E
I
R
K
N
T
Y
R
T
L
D
S
L
E
Site 222
S1668
N
T
Y
R
T
L
D
S
L
E
Q
T
I
K
Q
Site 223
T1672
T
L
D
S
L
E
Q
T
I
K
Q
L
E
N
T
Site 224
S1681
K
Q
L
E
N
T
I
S
E
M
S
P
K
A
L
Site 225
S1684
E
N
T
I
S
E
M
S
P
K
A
L
V
D
T
Site 226
T1691
S
P
K
A
L
V
D
T
S
C
S
S
N
R
D
Site 227
S1692
P
K
A
L
V
D
T
S
C
S
S
N
R
D
S
Site 228
S1694
A
L
V
D
T
S
C
S
S
N
R
D
S
V
A
Site 229
S1695
L
V
D
T
S
C
S
S
N
R
D
S
V
A
S
Site 230
S1699
S
C
S
S
N
R
D
S
V
A
S
S
S
H
I
Site 231
S1702
S
N
R
D
S
V
A
S
S
S
H
I
A
Q
E
Site 232
S1703
N
R
D
S
V
A
S
S
S
H
I
A
Q
E
A
Site 233
S1704
R
D
S
V
A
S
S
S
H
I
A
Q
E
A
S
Site 234
S1711
S
H
I
A
Q
E
A
S
P
R
P
L
L
V
P
Site 235
T1729
P
T
A
L
E
P
P
T
S
I
P
S
A
S
R
Site 236
S1730
T
A
L
E
P
P
T
S
I
P
S
A
S
R
K
Site 237
S1733
E
P
P
T
S
I
P
S
A
S
R
K
G
S
S
Site 238
S1735
P
T
S
I
P
S
A
S
R
K
G
S
S
G
A
Site 239
S1739
P
S
A
S
R
K
G
S
S
G
A
P
Q
T
S
Site 240
S1740
S
A
S
R
K
G
S
S
G
A
P
Q
T
S
R
Site 241
T1745
G
S
S
G
A
P
Q
T
S
R
M
P
V
P
M
Site 242
S1746
S
S
G
A
P
Q
T
S
R
M
P
V
P
M
S
Site 243
S1753
S
R
M
P
V
P
M
S
A
K
N
R
P
G
T
Site 244
T1760
S
A
K
N
R
P
G
T
L
D
K
P
G
K
Q
Site 245
Y1776
K
L
Q
D
P
R
Q
Y
R
Q
A
N
G
S
A
Site 246
S1782
Q
Y
R
Q
A
N
G
S
A
K
K
S
G
G
D
Site 247
S1786
A
N
G
S
A
K
K
S
G
G
D
F
K
P
T
Site 248
T1793
S
G
G
D
F
K
P
T
S
P
S
L
P
A
S
Site 249
S1794
G
G
D
F
K
P
T
S
P
S
L
P
A
S
K
Site 250
S1796
D
F
K
P
T
S
P
S
L
P
A
S
K
I
P
Site 251
S1800
T
S
P
S
L
P
A
S
K
I
P
A
L
S
P
Site 252
S1806
A
S
K
I
P
A
L
S
P
S
S
G
K
S
S
Site 253
S1808
K
I
P
A
L
S
P
S
S
G
K
S
S
S
L
Site 254
S1809
I
P
A
L
S
P
S
S
G
K
S
S
S
L
P
Site 255
S1812
L
S
P
S
S
G
K
S
S
S
L
P
S
S
S
Site 256
S1813
S
P
S
S
G
K
S
S
S
L
P
S
S
S
G
Site 257
S1814
P
S
S
G
K
S
S
S
L
P
S
S
S
G
D
Site 258
S1817
G
K
S
S
S
L
P
S
S
S
G
D
S
S
N
Site 259
S1818
K
S
S
S
L
P
S
S
S
G
D
S
S
N
L
Site 260
S1819
S
S
S
L
P
S
S
S
G
D
S
S
N
L
P
Site 261
S1822
L
P
S
S
S
G
D
S
S
N
L
P
N
P
P
Site 262
S1823
P
S
S
S
G
D
S
S
N
L
P
N
P
P
A
Site 263
T1831
N
L
P
N
P
P
A
T
K
P
S
I
A
S
N
Site 264
S1834
N
P
P
A
T
K
P
S
I
A
S
N
P
L
S
Site 265
S1837
A
T
K
P
S
I
A
S
N
P
L
S
P
Q
T
Site 266
S1841
S
I
A
S
N
P
L
S
P
Q
T
G
P
P
A
Site 267
T1844
S
N
P
L
S
P
Q
T
G
P
P
A
H
S
A
Site 268
S1850
Q
T
G
P
P
A
H
S
A
S
L
I
P
S
V
Site 269
S1852
G
P
P
A
H
S
A
S
L
I
P
S
V
S
N
Site 270
S1856
H
S
A
S
L
I
P
S
V
S
N
G
S
L
K
Site 271
S1861
I
P
S
V
S
N
G
S
L
K
F
Q
S
L
T
Site 272
S1866
N
G
S
L
K
F
Q
S
L
T
H
T
G
K
G
Site 273
T1868
S
L
K
F
Q
S
L
T
H
T
G
K
G
H
H
Site 274
T1870
K
F
Q
S
L
T
H
T
G
K
G
H
H
L
S
Site 275
S1877
T
G
K
G
H
H
L
S
F
S
P
Q
S
Q
N
Site 276
S1879
K
G
H
H
L
S
F
S
P
Q
S
Q
N
G
R
Site 277
S1882
H
L
S
F
S
P
Q
S
Q
N
G
R
A
P
P
Site 278
S1892
G
R
A
P
P
P
L
S
F
S
S
S
P
P
S
Site 279
S1894
A
P
P
P
L
S
F
S
S
S
P
P
S
P
A
Site 280
S1895
P
P
P
L
S
F
S
S
S
P
P
S
P
A
S
Site 281
S1896
P
P
L
S
F
S
S
S
P
P
S
P
A
S
S
Site 282
S1899
S
F
S
S
S
P
P
S
P
A
S
S
V
S
L
Site 283
S1902
S
S
P
P
S
P
A
S
S
V
S
L
N
Q
G
Site 284
S1903
S
P
P
S
P
A
S
S
V
S
L
N
Q
G
A
Site 285
S1905
P
S
P
A
S
S
V
S
L
N
Q
G
A
K
G
Site 286
T1915
Q
G
A
K
G
T
R
T
I
H
T
P
S
L
T
Site 287
T1918
K
G
T
R
T
I
H
T
P
S
L
T
S
Y
K
Site 288
S1920
T
R
T
I
H
T
P
S
L
T
S
Y
K
A
Q
Site 289
Y1924
H
T
P
S
L
T
S
Y
K
A
Q
N
G
S
S
Site 290
S1930
S
Y
K
A
Q
N
G
S
S
S
K
A
T
P
S
Site 291
S1932
K
A
Q
N
G
S
S
S
K
A
T
P
S
T
A
Site 292
T1935
N
G
S
S
S
K
A
T
P
S
T
A
K
E
T
Site 293
S1937
S
S
S
K
A
T
P
S
T
A
K
E
T
S
_
Site 294
T1938
S
S
K
A
T
P
S
T
A
K
E
T
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
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2019 Kinexus Bioinformatics Corporation