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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYCP2L
Full Name:
Synaptonemal complex protein 2-like
Alias:
145 kDa nucleolar protein homolog
Type:
Mass (Da):
93599
Number AA:
812
UniProt ID:
Q5T4T6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y46
G
F
Q
K
I
K
E
Y
F
Q
Q
K
E
S
H
Site 2
Y58
E
S
H
F
P
Q
K
Y
N
R
L
L
L
Y
R
Site 3
Y64
K
Y
N
R
L
L
L
Y
R
L
D
R
S
I
N
Site 4
S69
L
L
Y
R
L
D
R
S
I
N
K
E
L
D
K
Site 5
S81
L
D
K
N
E
F
Q
S
V
S
L
L
L
K
C
Site 6
S83
K
N
E
F
Q
S
V
S
L
L
L
K
C
I
Q
Site 7
T121
V
S
W
F
E
R
T
T
G
I
L
T
S
E
G
Site 8
S126
R
T
T
G
I
L
T
S
E
G
L
A
S
D
T
Site 9
S150
F
D
T
A
L
I
I
S
R
S
S
S
E
G
K
Site 10
S152
T
A
L
I
I
S
R
S
S
S
E
G
K
I
Q
Site 11
S153
A
L
I
I
S
R
S
S
S
E
G
K
I
Q
M
Site 12
T176
G
F
L
V
T
E
K
T
V
N
H
L
L
Q
Q
Site 13
S207
E
R
K
K
F
P
L
S
E
G
M
C
H
L
M
Site 14
T223
D
L
A
R
T
L
L
T
V
G
D
Y
D
Q
Q
Site 15
T241
S
E
A
L
C
R
L
T
I
K
K
S
R
D
E
Site 16
S245
C
R
L
T
I
K
K
S
R
D
E
L
V
H
K
Site 17
S275
D
R
E
F
E
T
D
S
R
R
F
L
N
H
L
Site 18
Y293
L
G
D
Q
R
R
V
Y
S
F
P
C
I
A
A
Site 19
S294
G
D
Q
R
R
V
Y
S
F
P
C
I
A
A
F
Site 20
S328
D
F
N
L
G
S
Q
S
V
T
F
Y
I
D
N
Site 21
T330
N
L
G
S
Q
S
V
T
F
Y
I
D
N
A
E
Site 22
Y332
G
S
Q
S
V
T
F
Y
I
D
N
A
E
N
T
Site 23
T339
Y
I
D
N
A
E
N
T
L
W
D
S
V
T
L
Site 24
S343
A
E
N
T
L
W
D
S
V
T
L
P
K
E
A
Site 25
T345
N
T
L
W
D
S
V
T
L
P
K
E
A
V
M
Site 26
Y377
K
K
P
M
I
I
S
Y
K
E
V
M
K
I
E
Site 27
T412
K
Q
M
L
P
D
Q
T
K
I
S
S
E
L
F
Site 28
S415
L
P
D
Q
T
K
I
S
S
E
L
F
S
K
S
Site 29
S416
P
D
Q
T
K
I
S
S
E
L
F
S
K
S
D
Site 30
S420
K
I
S
S
E
L
F
S
K
S
D
K
E
D
R
Site 31
S422
S
S
E
L
F
S
K
S
D
K
E
D
R
E
S
Site 32
S429
S
D
K
E
D
R
E
S
P
S
G
L
E
R
E
Site 33
T437
P
S
G
L
E
R
E
T
E
Q
A
E
E
S
T
Site 34
S443
E
T
E
Q
A
E
E
S
T
N
M
V
E
F
M
Site 35
S467
T
L
H
L
N
D
Q
S
E
P
P
V
I
G
E
Site 36
S477
P
V
I
G
E
P
A
S
D
S
H
L
Q
P
V
Site 37
S506
H
Y
R
K
H
L
F
S
E
S
N
Q
D
S
S
Site 38
S508
R
K
H
L
F
S
E
S
N
Q
D
S
S
T
S
Site 39
S512
F
S
E
S
N
Q
D
S
S
T
S
E
L
S
W
Site 40
S513
S
E
S
N
Q
D
S
S
T
S
E
L
S
W
T
Site 41
T514
E
S
N
Q
D
S
S
T
S
E
L
S
W
T
S
Site 42
S515
S
N
Q
D
S
S
T
S
E
L
S
W
T
S
N
Site 43
S518
D
S
S
T
S
E
L
S
W
T
S
N
Q
K
K
Site 44
T520
S
T
S
E
L
S
W
T
S
N
Q
K
K
K
S
Site 45
S521
T
S
E
L
S
W
T
S
N
Q
K
K
K
S
L
Site 46
S527
T
S
N
Q
K
K
K
S
L
K
S
Y
S
S
R
Site 47
S530
Q
K
K
K
S
L
K
S
Y
S
S
R
K
K
T
Site 48
Y531
K
K
K
S
L
K
S
Y
S
S
R
K
K
T
R
Site 49
S532
K
K
S
L
K
S
Y
S
S
R
K
K
T
R
T
Site 50
S533
K
S
L
K
S
Y
S
S
R
K
K
T
R
T
R
Site 51
T537
S
Y
S
S
R
K
K
T
R
T
R
S
N
L
R
Site 52
T539
S
S
R
K
K
T
R
T
R
S
N
L
R
I
L
Site 53
S541
R
K
K
T
R
T
R
S
N
L
R
I
L
P
V
Site 54
S552
I
L
P
V
F
P
P
S
S
G
S
G
H
E
K
Site 55
S553
L
P
V
F
P
P
S
S
G
S
G
H
E
K
D
Site 56
S566
K
D
Q
A
K
L
L
S
P
S
E
K
E
I
P
Site 57
S568
Q
A
K
L
L
S
P
S
E
K
E
I
P
E
Q
Site 58
T578
E
I
P
E
Q
N
N
T
T
S
P
K
T
S
E
Site 59
S580
P
E
Q
N
N
T
T
S
P
K
T
S
E
Q
K
Site 60
S584
N
T
T
S
P
K
T
S
E
Q
K
F
Q
D
S
Site 61
S591
S
E
Q
K
F
Q
D
S
F
A
F
L
T
A
E
Site 62
T596
Q
D
S
F
A
F
L
T
A
E
D
S
A
Q
K
Site 63
S600
A
F
L
T
A
E
D
S
A
Q
K
T
E
L
Q
Site 64
T604
A
E
D
S
A
Q
K
T
E
L
Q
D
P
H
S
Site 65
S611
T
E
L
Q
D
P
H
S
L
S
E
L
S
S
L
Site 66
S613
L
Q
D
P
H
S
L
S
E
L
S
S
L
K
H
Site 67
S617
H
S
L
S
E
L
S
S
L
K
H
S
E
D
E
Site 68
S621
E
L
S
S
L
K
H
S
E
D
E
E
K
P
K
Site 69
S634
P
K
I
V
N
Q
E
S
L
T
E
S
T
S
L
Site 70
T636
I
V
N
Q
E
S
L
T
E
S
T
S
L
K
H
Site 71
S638
N
Q
E
S
L
T
E
S
T
S
L
K
H
K
L
Site 72
S640
E
S
L
T
E
S
T
S
L
K
H
K
L
R
N
Site 73
S657
D
K
D
I
P
E
G
S
F
A
K
S
Q
Q
S
Site 74
S661
P
E
G
S
F
A
K
S
Q
Q
S
R
L
E
E
Site 75
S674
E
E
E
V
A
P
G
S
P
F
S
I
T
E
E
Site 76
S677
V
A
P
G
S
P
F
S
I
T
E
E
R
E
L
Site 77
T679
P
G
S
P
F
S
I
T
E
E
R
E
L
P
E
Site 78
S689
R
E
L
P
E
G
I
S
T
S
S
L
E
V
V
Site 79
S692
P
E
G
I
S
T
S
S
L
E
V
V
P
E
N
Site 80
T708
N
G
S
A
I
L
P
T
F
E
N
F
T
K
K
Site 81
Y720
T
K
K
R
K
R
K
Y
E
L
R
Y
R
K
R
Site 82
S797
K
Q
S
A
D
L
Q
S
F
C
D
L
Q
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation