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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCC10
Full Name:
Multidrug resistance-associated protein 7
Alias:
ATP-binding cassette sub- family C member 10; ATP-binding cassette, sub-family C (CFTR/MRP) member 10; EST182763; MRP7; multidrug resistance-associated 7; SIMRP7
Type:
Transporter
Mass (Da):
161630
Number AA:
UniProt ID:
Q5T3U5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0042626
PhosphoSite+
KinaseNET
Biological Process:
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T52
L
S
A
C
Y
L
G
T
P
R
S
P
D
Y
I
Site 2
S55
C
Y
L
G
T
P
R
S
P
D
Y
I
L
P
C
Site 3
Y58
G
T
P
R
S
P
D
Y
I
L
P
C
S
P
G
Site 4
S63
P
D
Y
I
L
P
C
S
P
G
W
R
L
R
L
Site 5
S125
A
L
W
V
L
A
H
S
P
H
G
H
S
R
G
Site 6
S130
A
H
S
P
H
G
H
S
R
G
P
L
A
L
A
Site 7
S219
E
V
A
E
D
G
E
S
W
L
S
R
F
S
Y
Site 8
S222
E
D
G
E
S
W
L
S
R
F
S
Y
A
W
L
Site 9
S225
E
S
W
L
S
R
F
S
Y
A
W
L
A
P
L
Site 10
Y258
P
H
R
L
Q
P
T
Y
L
A
R
V
F
Q
A
Site 11
Y278
A
R
L
W
R
A
L
Y
G
A
F
G
R
C
Y
Site 12
S321
E
E
G
Q
E
P
L
S
H
G
L
L
Y
A
L
Site 13
S373
K
A
L
Q
L
G
P
S
R
P
P
T
G
E
A
Site 14
T377
L
G
P
S
R
P
P
T
G
E
A
L
N
L
L
Site 15
T386
E
A
L
N
L
L
G
T
D
S
E
R
L
L
N
Site 16
T463
D
A
R
V
K
L
V
T
E
L
L
S
G
I
R
Site 17
S467
K
L
V
T
E
L
L
S
G
I
R
V
I
K
F
Site 18
Y585
P
N
H
N
P
Q
A
Y
Y
S
P
D
P
P
A
Site 19
S587
H
N
P
Q
A
Y
Y
S
P
D
P
P
A
E
P
Site 20
S595
P
D
P
P
A
E
P
S
T
V
L
E
L
H
G
Site 21
T596
D
P
P
A
E
P
S
T
V
L
E
L
H
G
A
Site 22
S606
E
L
H
G
A
L
F
S
W
D
P
V
G
T
S
Site 23
S613
S
W
D
P
V
G
T
S
L
E
T
F
I
S
H
Site 24
S619
T
S
L
E
T
F
I
S
H
L
E
V
K
K
G
Site 25
S663
H
V
A
V
R
G
L
S
K
G
F
G
L
A
T
Site 26
T670
S
K
G
F
G
L
A
T
Q
E
P
W
I
Q
F
Site 27
T679
E
P
W
I
Q
F
A
T
I
R
D
N
I
L
F
Site 28
T689
D
N
I
L
F
G
K
T
F
D
A
Q
L
Y
K
Site 29
Y695
K
T
F
D
A
Q
L
Y
K
E
V
L
E
A
C
Site 30
T717
I
L
P
A
G
D
Q
T
E
V
G
E
K
G
V
Site 31
T725
E
V
G
E
K
G
V
T
L
S
G
G
Q
R
A
Site 32
S727
G
E
K
G
V
T
L
S
G
G
Q
R
A
R
I
Site 33
Y747
V
Y
Q
E
K
E
L
Y
L
L
D
D
P
L
A
Site 34
Y787
L
C
T
H
R
T
E
Y
L
E
R
A
D
A
V
Site 35
S831
E
N
G
Q
E
S
D
S
A
T
A
Q
S
V
Q
Site 36
T833
G
Q
E
S
D
S
A
T
A
Q
S
V
Q
N
P
Site 37
S852
E
G
L
E
E
E
Q
S
T
S
G
R
L
L
Q
Site 38
T853
G
L
E
E
E
Q
S
T
S
G
R
L
L
Q
E
Site 39
S854
L
E
E
E
Q
S
T
S
G
R
L
L
Q
E
E
Site 40
Y873
G
A
V
A
L
H
V
Y
Q
A
Y
W
K
A
V
Site 41
Y876
A
L
H
V
Y
Q
A
Y
W
K
A
V
G
Q
G
Site 42
S918
S
Q
L
K
A
E
N
S
S
Q
E
A
Q
P
S
Site 43
S919
Q
L
K
A
E
N
S
S
Q
E
A
Q
P
S
T
Site 44
S925
S
S
Q
E
A
Q
P
S
T
S
P
A
S
M
G
Site 45
T926
S
Q
E
A
Q
P
S
T
S
P
A
S
M
G
L
Site 46
S927
Q
E
A
Q
P
S
T
S
P
A
S
M
G
L
F
Site 47
S930
Q
P
S
T
S
P
A
S
M
G
L
F
S
P
Q
Site 48
S962
K
A
A
P
N
G
S
S
D
I
R
F
Y
L
T
Site 49
T999
G
T
L
Q
A
A
A
T
L
H
R
R
L
L
H
Site 50
T1021
T
F
F
N
A
T
P
T
G
R
I
L
N
R
F
Site 51
S1029
G
R
I
L
N
R
F
S
S
D
V
A
C
A
D
Site 52
S1030
R
I
L
N
R
F
S
S
D
V
A
C
A
D
D
Site 53
Y1078
L
P
P
L
S
I
M
Y
Y
H
V
Q
R
H
Y
Site 54
Y1079
P
P
L
S
I
M
Y
Y
H
V
Q
R
H
Y
R
Site 55
Y1085
Y
Y
H
V
Q
R
H
Y
R
A
S
S
R
E
L
Site 56
S1088
V
Q
R
H
Y
R
A
S
S
R
E
L
R
R
L
Site 57
S1089
Q
R
H
Y
R
A
S
S
R
E
L
R
R
L
G
Site 58
S1097
R
E
L
R
R
L
G
S
L
T
L
S
P
L
Y
Site 59
T1099
L
R
R
L
G
S
L
T
L
S
P
L
Y
S
H
Site 60
T1123
V
L
R
A
T
G
A
T
Y
R
F
E
E
E
N
Site 61
S1214
Q
T
E
A
M
L
V
S
V
E
R
L
E
E
Y
Site 62
Y1221
S
V
E
R
L
E
E
Y
T
C
D
L
P
Q
E
Site 63
T1282
K
L
G
I
V
G
R
T
G
S
G
K
S
S
L
Site 64
T1336
E
P
F
L
F
S
G
T
V
R
E
N
L
D
P
Site 65
S1367
H
L
S
E
V
I
T
S
M
G
G
L
D
G
E
Site 66
S1381
E
L
G
E
G
G
R
S
L
S
L
G
Q
R
Q
Site 67
S1383
G
E
G
G
R
S
L
S
L
G
Q
R
Q
L
L
Site 68
S1411
C
I
D
E
A
T
A
S
V
D
Q
K
T
D
Q
Site 69
T1416
T
A
S
V
D
Q
K
T
D
Q
L
L
Q
Q
T
Site 70
T1432
C
K
R
F
A
N
K
T
V
L
T
I
A
H
R
Site 71
T1442
T
I
A
H
R
L
N
T
I
L
N
S
D
R
V
Site 72
S1462
G
R
V
V
E
L
D
S
P
A
T
L
R
N
Q
Site 73
T1465
V
E
L
D
S
P
A
T
L
R
N
Q
P
H
S
Site 74
S1472
T
L
R
N
Q
P
H
S
L
F
Q
Q
L
L
Q
Site 75
S1481
F
Q
Q
L
L
Q
S
S
Q
Q
G
V
P
A
S
Site 76
S1488
S
Q
Q
G
V
P
A
S
L
G
G
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation