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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGAP10
Full Name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 10
Alias:
Centaurin-gamma-like family member 7
Type:
Mass (Da):
72707
Number AA:
658
UniProt ID:
Q5T2P9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
T
C
R
V
H
P
S
V
S
L
E
F
D
Q
Site 2
S23
E
F
D
Q
Q
Q
G
S
V
C
P
S
E
S
E
Site 3
S27
Q
Q
G
S
V
C
P
S
E
S
E
I
Y
E
A
Site 4
S29
G
S
V
C
P
S
E
S
E
I
Y
E
A
G
A
Site 5
Y32
C
P
S
E
S
E
I
Y
E
A
G
A
E
D
R
Site 6
S81
E
A
L
E
F
N
L
S
A
N
P
E
A
S
T
Site 7
S94
S
T
I
F
Q
R
N
S
Q
T
D
A
L
E
F
Site 8
S104
D
A
L
E
F
N
S
S
A
N
P
E
A
S
T
Site 9
S110
S
S
A
N
P
E
A
S
T
I
F
Q
R
N
S
Site 10
S117
S
T
I
F
Q
R
N
S
Q
T
D
V
V
E
I
Site 11
S127
D
V
V
E
I
R
R
S
N
C
T
N
H
V
S
Site 12
T130
E
I
R
R
S
N
C
T
N
H
V
S
T
E
R
Site 13
S134
S
N
C
T
N
H
V
S
T
E
R
F
S
Q
Q
Site 14
T135
N
C
T
N
H
V
S
T
E
R
F
S
Q
Q
Y
Site 15
S139
H
V
S
T
E
R
F
S
Q
Q
Y
S
S
C
S
Site 16
Y142
T
E
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
Site 17
S143
E
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
L
Site 18
S144
R
F
S
Q
Q
Y
S
S
C
S
T
I
F
L
D
Site 19
S146
S
Q
Q
Y
S
S
C
S
T
I
F
L
D
D
S
Site 20
T176
L
E
I
P
H
H
I
T
Q
R
D
A
D
R
S
Site 21
S183
T
Q
R
D
A
D
R
S
L
S
I
P
D
E
Q
Site 22
S185
R
D
A
D
R
S
L
S
I
P
D
E
Q
L
H
Site 23
S193
I
P
D
E
Q
L
H
S
F
A
V
S
T
V
H
Site 24
S210
K
K
R
N
G
G
G
S
L
N
N
Y
S
S
S
Site 25
Y214
G
G
G
S
L
N
N
Y
S
S
S
I
P
P
T
Site 26
S215
G
G
S
L
N
N
Y
S
S
S
I
P
P
T
P
Site 27
S216
G
S
L
N
N
Y
S
S
S
I
P
P
T
P
S
Site 28
S217
S
L
N
N
Y
S
S
S
I
P
P
T
P
S
T
Site 29
T221
Y
S
S
S
I
P
P
T
P
S
T
S
Q
E
D
Site 30
S223
S
S
I
P
P
T
P
S
T
S
Q
E
D
P
Q
Site 31
T224
S
I
P
P
T
P
S
T
S
Q
E
D
P
Q
F
Site 32
S225
I
P
P
T
P
S
T
S
Q
E
D
P
Q
F
S
Site 33
S232
S
Q
E
D
P
Q
F
S
V
P
P
T
A
N
T
Site 34
T236
P
Q
F
S
V
P
P
T
A
N
T
P
T
P
V
Site 35
T239
S
V
P
P
T
A
N
T
P
T
P
V
C
K
L
Site 36
T241
P
P
T
A
N
T
P
T
P
V
C
K
L
S
M
Site 37
S251
C
K
L
S
M
R
W
S
N
L
F
T
S
E
K
Site 38
T255
M
R
W
S
N
L
F
T
S
E
K
G
S
D
P
Site 39
S256
R
W
S
N
L
F
T
S
E
K
G
S
D
P
D
Site 40
S260
L
F
T
S
E
K
G
S
D
P
D
K
E
R
K
Site 41
T275
A
P
E
N
H
A
D
T
I
G
S
G
R
A
I
Site 42
S278
N
H
A
D
T
I
G
S
G
R
A
I
P
I
K
Site 43
T299
R
S
G
K
W
L
K
T
W
K
K
K
Y
V
T
Site 44
Y304
L
K
T
W
K
K
K
Y
V
T
L
C
S
N
G
Site 45
T306
T
W
K
K
K
Y
V
T
L
C
S
N
G
V
L
Site 46
Y315
C
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
Site 47
Y316
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
Site 48
S318
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
K
N
Site 49
Y322
Y
Y
S
S
L
G
D
Y
M
K
N
I
H
K
K
Site 50
S336
K
E
I
D
L
R
T
S
T
I
K
V
P
G
K
Site 51
T337
E
I
D
L
R
T
S
T
I
K
V
P
G
K
W
Site 52
S346
K
V
P
G
K
W
P
S
L
A
T
S
A
C
A
Site 53
S356
T
S
A
C
A
P
I
S
S
S
K
S
N
G
L
Site 54
S357
S
A
C
A
P
I
S
S
S
K
S
N
G
L
S
Site 55
S358
A
C
A
P
I
S
S
S
K
S
N
G
L
S
K
Site 56
S360
A
P
I
S
S
S
K
S
N
G
L
S
K
D
M
Site 57
S364
S
S
K
S
N
G
L
S
K
D
M
D
T
G
L
Site 58
T369
G
L
S
K
D
M
D
T
G
L
G
D
S
I
C
Site 59
S383
C
F
S
P
G
I
S
S
T
T
S
P
K
L
N
Site 60
T384
F
S
P
G
I
S
S
T
T
S
P
K
L
N
P
Site 61
S386
P
G
I
S
S
T
T
S
P
K
L
N
P
P
P
Site 62
S394
P
K
L
N
P
P
P
S
P
H
A
N
K
K
K
Site 63
Y428
W
H
F
E
A
T
T
Y
E
E
R
D
A
W
V
Site 64
S445
I
Q
S
Q
I
L
A
S
L
Q
S
C
K
S
S
Site 65
S448
Q
I
L
A
S
L
Q
S
C
K
S
S
K
S
K
Site 66
S451
A
S
L
Q
S
C
K
S
S
K
S
K
S
Q
L
Site 67
S452
S
L
Q
S
C
K
S
S
K
S
K
S
Q
L
T
Site 68
S454
Q
S
C
K
S
S
K
S
K
S
Q
L
T
S
Q
Site 69
S456
C
K
S
S
K
S
K
S
Q
L
T
S
Q
S
E
Site 70
S460
K
S
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Site 71
S462
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Q
S
Site 72
S508
E
C
S
G
I
H
R
S
F
G
T
R
L
S
R
Site 73
S514
R
S
F
G
T
R
L
S
R
V
R
S
L
E
L
Site 74
S518
T
R
L
S
R
V
R
S
L
E
L
D
D
W
P
Site 75
S534
E
L
R
K
V
M
S
S
I
G
N
E
L
A
N
Site 76
S542
I
G
N
E
L
A
N
S
I
W
E
G
S
S
Q
Site 77
T552
E
G
S
S
Q
G
Q
T
K
P
S
I
K
S
T
Site 78
S555
S
Q
G
Q
T
K
P
S
I
K
S
T
R
E
E
Site 79
S558
Q
T
K
P
S
I
K
S
T
R
E
E
K
E
W
Site 80
T559
T
K
P
S
I
K
S
T
R
E
E
K
E
W
W
Site 81
Y571
E
W
W
I
R
S
K
Y
E
E
K
L
F
L
A
Site 82
T595
G
Q
Q
L
L
R
A
T
T
D
E
D
L
Q
T
Site 83
T596
Q
Q
L
L
R
A
T
T
D
E
D
L
Q
T
A
Site 84
T618
S
R
E
E
V
N
E
T
C
G
E
G
D
G
C
Site 85
T647
E
Q
L
L
T
G
W
T
S
W
P
E
M
P
T
Site 86
S648
Q
L
L
T
G
W
T
S
W
P
E
M
P
T
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation