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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AKNAD1
Full Name:
Protein AKNAD1
Alias:
Type:
Mass (Da):
92891
Number AA:
836
UniProt ID:
Q5T1N1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
A
D
F
S
E
H
T
T
Y
K
Q
E
D
L
P
Site 2
Y12
D
F
S
E
H
T
T
Y
K
Q
E
D
L
P
Y
Site 3
Y19
Y
K
Q
E
D
L
P
Y
D
G
D
L
S
Q
I
Site 4
S24
L
P
Y
D
G
D
L
S
Q
I
K
I
G
N
D
Site 5
Y32
Q
I
K
I
G
N
D
Y
S
F
T
S
K
K
D
Site 6
S33
I
K
I
G
N
D
Y
S
F
T
S
K
K
D
G
Site 7
S36
G
N
D
Y
S
F
T
S
K
K
D
G
L
E
V
Site 8
T92
D
E
K
E
K
Q
C
T
A
A
L
H
I
P
A
Site 9
S105
P
A
N
E
G
D
A
S
K
S
S
I
S
D
I
Site 10
S107
N
E
G
D
A
S
K
S
S
I
S
D
I
L
L
Site 11
S108
E
G
D
A
S
K
S
S
I
S
D
I
L
L
H
Site 12
S110
D
A
S
K
S
S
I
S
D
I
L
L
H
H
L
Site 13
S118
D
I
L
L
H
H
L
S
K
E
P
F
L
R
G
Site 14
T132
G
Q
G
I
D
C
E
T
L
P
E
I
S
N
A
Site 15
S141
P
E
I
S
N
A
D
S
F
E
E
E
A
I
I
Site 16
Y155
I
K
S
I
I
S
C
Y
N
K
N
S
W
P
K
Site 17
T165
N
S
W
P
K
E
Q
T
P
E
L
T
D
Q
L
Site 18
S181
P
K
R
D
G
E
N
S
N
K
P
G
S
A
T
Site 19
S186
E
N
S
N
K
P
G
S
A
T
T
T
E
E
N
Site 20
T190
K
P
G
S
A
T
T
T
E
E
N
T
S
D
L
Site 21
S195
T
T
T
E
E
N
T
S
D
L
E
G
P
V
A
Site 22
S207
P
V
A
A
G
D
S
S
H
Q
E
N
V
N
V
Site 23
T218
N
V
N
V
L
T
K
T
K
G
P
G
D
K
Q
Site 24
S227
G
P
G
D
K
Q
K
S
Y
Q
G
Q
S
P
Q
Site 25
Y228
P
G
D
K
Q
K
S
Y
Q
G
Q
S
P
Q
K
Site 26
S232
Q
K
S
Y
Q
G
Q
S
P
Q
K
Q
Q
T
E
Site 27
S243
Q
Q
T
E
K
A
N
S
G
N
T
F
K
Y
G
Site 28
T246
E
K
A
N
S
G
N
T
F
K
Y
G
Q
G
Q
Site 29
Y249
N
S
G
N
T
F
K
Y
G
Q
G
Q
V
H
Y
Site 30
Y256
Y
G
Q
G
Q
V
H
Y
Q
L
P
D
F
S
K
Site 31
S262
H
Y
Q
L
P
D
F
S
K
I
A
P
K
V
K
Site 32
S287
L
A
I
A
K
Q
A
S
F
S
S
K
S
R
D
Site 33
S290
A
K
Q
A
S
F
S
S
K
S
R
D
K
P
T
Site 34
S292
Q
A
S
F
S
S
K
S
R
D
K
P
T
L
V
Site 35
T297
S
K
S
R
D
K
P
T
L
V
Q
D
S
L
E
Site 36
S302
K
P
T
L
V
Q
D
S
L
E
T
T
P
E
S
Site 37
T306
V
Q
D
S
L
E
T
T
P
E
S
N
C
V
E
Site 38
S309
S
L
E
T
T
P
E
S
N
C
V
E
K
Q
H
Site 39
S327
K
G
K
I
T
E
P
S
Q
Q
I
Q
M
E
P
Site 40
T344
H
I
H
Q
E
L
L
T
G
I
E
S
E
A
S
Site 41
S351
T
G
I
E
S
E
A
S
L
S
K
L
S
P
T
Site 42
S353
I
E
S
E
A
S
L
S
K
L
S
P
T
S
Q
Site 43
S356
E
A
S
L
S
K
L
S
P
T
S
Q
K
G
T
Site 44
S359
L
S
K
L
S
P
T
S
Q
K
G
T
S
S
S
Site 45
T363
S
P
T
S
Q
K
G
T
S
S
S
S
S
Y
I
Site 46
S364
P
T
S
Q
K
G
T
S
S
S
S
S
Y
I
F
Site 47
S365
T
S
Q
K
G
T
S
S
S
S
S
Y
I
F
Q
Site 48
S366
S
Q
K
G
T
S
S
S
S
S
Y
I
F
Q
K
Site 49
S368
K
G
T
S
S
S
S
S
Y
I
F
Q
K
I
S
Site 50
Y369
G
T
S
S
S
S
S
Y
I
F
Q
K
I
S
Q
Site 51
S399
K
T
K
V
Q
E
F
S
K
R
I
K
Q
D
S
Site 52
S406
S
K
R
I
K
Q
D
S
P
Y
H
L
Q
D
K
Site 53
Y408
R
I
K
Q
D
S
P
Y
H
L
Q
D
K
K
L
Site 54
T440
A
T
K
D
K
H
L
T
L
Q
Q
Q
V
H
K
Site 55
S483
V
K
E
K
M
D
E
S
K
Y
T
S
A
P
S
Site 56
Y485
E
K
M
D
E
S
K
Y
T
S
A
P
S
L
P
Site 57
T486
K
M
D
E
S
K
Y
T
S
A
P
S
L
P
V
Site 58
S487
M
D
E
S
K
Y
T
S
A
P
S
L
P
V
S
Site 59
S490
S
K
Y
T
S
A
P
S
L
P
V
S
S
P
V
Site 60
S494
S
A
P
S
L
P
V
S
S
P
V
T
L
D
D
Site 61
T505
T
L
D
D
L
A
S
T
F
S
S
L
S
N
E
Site 62
S507
D
D
L
A
S
T
F
S
S
L
S
N
E
I
P
Site 63
S508
D
L
A
S
T
F
S
S
L
S
N
E
I
P
K
Site 64
S510
A
S
T
F
S
S
L
S
N
E
I
P
K
E
H
Site 65
S522
K
E
H
P
G
H
P
S
G
P
R
G
S
G
G
Site 66
S527
H
P
S
G
P
R
G
S
G
G
S
E
V
T
G
Site 67
S530
G
P
R
G
S
G
G
S
E
V
T
G
T
P
Q
Site 68
T533
G
S
G
G
S
E
V
T
G
T
P
Q
G
G
P
Site 69
T535
G
G
S
E
V
T
G
T
P
Q
G
G
P
Q
E
Site 70
T555
L
C
E
L
A
P
Q
T
Y
L
N
G
H
Y
G
Site 71
Y556
C
E
L
A
P
Q
T
Y
L
N
G
H
Y
G
D
Site 72
S578
D
Q
V
A
M
R
L
S
S
N
S
G
E
D
P
Site 73
S579
Q
V
A
M
R
L
S
S
N
S
G
E
D
P
N
Site 74
S581
A
M
R
L
S
S
N
S
G
E
D
P
N
G
T
Site 75
T588
S
G
E
D
P
N
G
T
P
R
R
Q
D
C
A
Site 76
T598
R
Q
D
C
A
E
M
T
A
P
S
P
S
C
A
Site 77
S603
E
M
T
A
P
S
P
S
C
A
F
C
R
R
L
Site 78
S631
R
I
N
C
G
R
F
S
I
V
L
H
E
K
A
Site 79
S641
L
H
E
K
A
P
H
S
D
S
T
P
N
S
D
Site 80
S643
E
K
A
P
H
S
D
S
T
P
N
S
D
T
G
Site 81
T644
K
A
P
H
S
D
S
T
P
N
S
D
T
G
H
Site 82
S647
H
S
D
S
T
P
N
S
D
T
G
H
S
F
C
Site 83
T649
D
S
T
P
N
S
D
T
G
H
S
F
C
S
D
Site 84
S652
P
N
S
D
T
G
H
S
F
C
S
D
S
G
T
Site 85
S655
D
T
G
H
S
F
C
S
D
S
G
T
E
M
Q
Site 86
S657
G
H
S
F
C
S
D
S
G
T
E
M
Q
S
N
Site 87
T659
S
F
C
S
D
S
G
T
E
M
Q
S
N
K
C
Site 88
T671
N
K
C
Q
D
C
G
T
K
I
P
T
S
R
R
Site 89
T675
D
C
G
T
K
I
P
T
S
R
R
A
C
R
K
Site 90
S676
C
G
T
K
I
P
T
S
R
R
A
C
R
K
E
Site 91
Y690
E
P
T
K
E
F
H
Y
R
Y
N
T
P
G
Q
Site 92
Y692
T
K
E
F
H
Y
R
Y
N
T
P
G
Q
N
Y
Site 93
T694
E
F
H
Y
R
Y
N
T
P
G
Q
N
Y
S
N
Site 94
S700
N
T
P
G
Q
N
Y
S
N
H
S
K
R
G
A
Site 95
S703
G
Q
N
Y
S
N
H
S
K
R
G
A
F
V
Q
Site 96
S713
G
A
F
V
Q
P
H
S
L
D
E
S
K
N
S
Site 97
S717
Q
P
H
S
L
D
E
S
K
N
S
S
P
S
F
Site 98
S720
S
L
D
E
S
K
N
S
S
P
S
F
L
K
P
Site 99
S721
L
D
E
S
K
N
S
S
P
S
F
L
K
P
K
Site 100
S723
E
S
K
N
S
S
P
S
F
L
K
P
K
R
I
Site 101
S732
L
K
P
K
R
I
C
S
Q
R
V
N
S
K
S
Site 102
S737
I
C
S
Q
R
V
N
S
K
S
F
K
G
E
H
Site 103
S739
S
Q
R
V
N
S
K
S
F
K
G
E
H
E
P
Site 104
T747
F
K
G
E
H
E
P
T
P
G
K
K
K
L
Q
Site 105
T758
K
K
L
Q
A
F
M
T
Y
S
S
D
P
A
T
Site 106
S761
Q
A
F
M
T
Y
S
S
D
P
A
T
P
S
P
Site 107
T765
T
Y
S
S
D
P
A
T
P
S
P
H
F
Y
S
Site 108
S767
S
S
D
P
A
T
P
S
P
H
F
Y
S
C
R
Site 109
Y771
A
T
P
S
P
H
F
Y
S
C
R
I
S
G
S
Site 110
S772
T
P
S
P
H
F
Y
S
C
R
I
S
G
S
K
Site 111
S776
H
F
Y
S
C
R
I
S
G
S
K
S
L
C
D
Site 112
S780
C
R
I
S
G
S
K
S
L
C
D
F
D
S
T
Site 113
S786
K
S
L
C
D
F
D
S
T
E
E
I
K
S
E
Site 114
T787
S
L
C
D
F
D
S
T
E
E
I
K
S
E
I
Site 115
S792
D
S
T
E
E
I
K
S
E
I
L
N
S
A
L
Site 116
T807
D
H
A
L
R
T
A
T
I
L
K
E
T
T
D
Site 117
T819
T
T
D
Q
M
I
K
T
I
A
E
D
L
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation