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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CC2D1B
Full Name:
Coiled-coil and C2 domain-containing protein 1B
Alias:
Type:
Mass (Da):
94224
Number AA:
858
UniProt ID:
Q5T0F9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T62
L
T
G
E
A
Q
T
T
G
K
K
P
A
P
K
Site 2
T142
E
E
N
G
L
E
D
T
E
P
P
V
Q
T
A
Site 3
S183
N
Y
R
E
A
A
A
S
A
K
E
A
G
E
A
Site 4
T202
R
C
E
R
G
L
K
T
L
E
S
Q
L
A
S
Site 5
S205
R
G
L
K
T
L
E
S
Q
L
A
S
V
R
R
Site 6
S209
T
L
E
S
Q
L
A
S
V
R
R
G
R
K
I
Site 7
S241
P
Q
E
P
A
N
R
S
P
E
T
D
P
P
A
Site 8
T244
P
A
N
R
S
P
E
T
D
P
P
A
P
P
A
Site 9
S254
P
A
P
P
A
L
E
S
D
N
P
S
Q
P
E
Site 10
S258
A
L
E
S
D
N
P
S
Q
P
E
T
S
L
P
Site 11
T262
D
N
P
S
Q
P
E
T
S
L
P
G
I
S
A
Site 12
S263
N
P
S
Q
P
E
T
S
L
P
G
I
S
A
Q
Site 13
S268
E
T
S
L
P
G
I
S
A
Q
P
V
S
D
L
Site 14
S273
G
I
S
A
Q
P
V
S
D
L
D
P
D
P
R
Site 15
S284
P
D
P
R
A
L
L
S
S
R
Q
R
E
Y
K
Site 16
S285
D
P
R
A
L
L
S
S
R
Q
R
E
Y
K
V
Site 17
Y290
L
S
S
R
Q
R
E
Y
K
V
A
A
L
S
A
Site 18
S296
E
Y
K
V
A
A
L
S
A
K
R
A
G
E
L
Site 19
S332
K
G
Q
P
V
D
L
S
A
M
P
P
A
P
E
Site 20
S347
D
L
K
P
Q
Q
A
S
Q
A
P
T
A
P
S
Site 21
T351
Q
Q
A
S
Q
A
P
T
A
P
S
V
I
P
P
Site 22
T374
M
A
P
D
V
P
A
T
P
V
A
P
T
E
S
Site 23
T383
V
A
P
T
E
S
Q
T
V
L
D
A
L
Q
Q
Site 24
Y395
L
Q
Q
R
L
N
K
Y
R
E
A
G
I
Q
A
Site 25
Y421
H
E
R
I
A
K
Q
Y
Q
D
A
I
R
A
H
Site 26
S474
A
A
A
E
K
L
A
S
A
E
D
S
A
P
A
Site 27
S478
K
L
A
S
A
E
D
S
A
P
A
D
K
D
E
Site 28
T510
A
K
K
P
A
R
P
T
V
P
S
S
Q
R
L
Site 29
S513
P
A
R
P
T
V
P
S
S
Q
R
L
P
E
P
Site 30
S514
A
R
P
T
V
P
S
S
Q
R
L
P
E
P
R
Site 31
S523
R
L
P
E
P
R
A
S
S
S
K
E
S
P
S
Site 32
S524
L
P
E
P
R
A
S
S
S
K
E
S
P
S
P
Site 33
S525
P
E
P
R
A
S
S
S
K
E
S
P
S
P
S
Site 34
S528
R
A
S
S
S
K
E
S
P
S
P
S
V
R
E
Site 35
S530
S
S
S
K
E
S
P
S
P
S
V
R
E
Q
L
Site 36
S532
S
K
E
S
P
S
P
S
V
R
E
Q
L
A
L
Site 37
Y547
L
E
A
R
K
L
Q
Y
Q
R
A
A
L
Q
A
Site 38
S557
A
A
L
Q
A
K
R
S
Q
D
L
E
Q
A
K
Site 39
Y566
D
L
E
Q
A
K
A
Y
L
R
V
A
K
W
L
Site 40
S582
A
Q
I
I
Q
A
R
S
G
R
P
V
D
L
S
Site 41
S589
S
G
R
P
V
D
L
S
K
V
P
S
P
L
T
Site 42
S593
V
D
L
S
K
V
P
S
P
L
T
D
E
E
G
Site 43
T596
S
K
V
P
S
P
L
T
D
E
E
G
D
F
I
Site 44
S613
H
H
E
D
L
R
L
S
Q
K
A
E
E
V
Y
Site 45
T679
A
Q
G
L
D
P
P
T
H
H
F
E
L
K
T
Site 46
T686
T
H
H
F
E
L
K
T
F
Q
T
V
R
I
F
Site 47
S694
F
Q
T
V
R
I
F
S
E
L
N
S
T
E
M
Site 48
T718
L
P
A
P
P
G
V
T
P
D
D
L
D
A
F
Site 49
Y732
F
V
R
F
E
F
H
Y
P
N
S
D
Q
A
Q
Site 50
S735
F
E
F
H
Y
P
N
S
D
Q
A
Q
K
S
K
Site 51
S741
N
S
D
Q
A
Q
K
S
K
T
A
V
V
K
N
Site 52
T743
D
Q
A
Q
K
S
K
T
A
V
V
K
N
T
N
Site 53
T749
K
T
A
V
V
K
N
T
N
S
P
E
F
D
Q
Site 54
S751
A
V
V
K
N
T
N
S
P
E
F
D
Q
L
F
Site 55
S787
F
E
I
F
H
K
G
S
F
F
R
S
D
K
L
Site 56
S791
H
K
G
S
F
F
R
S
D
K
L
V
G
T
A
Site 57
T797
R
S
D
K
L
V
G
T
A
H
L
K
L
E
R
Site 58
T824
V
L
D
G
R
K
P
T
G
G
K
L
E
V
K
Site 59
S839
V
R
L
R
E
P
L
S
G
Q
D
V
Q
M
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation