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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C10orf93
Full Name:
TPR repeat-containing protein C10orf93
Alias:
Type:
Mass (Da):
173480
Number AA:
1530
UniProt ID:
Q5SR76
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
Q
E
L
A
R
A
E
S
Q
Q
D
A
A
S
L
Site 2
S20
E
S
Q
Q
D
A
A
S
L
K
K
A
Y
E
L
Site 3
S30
K
A
Y
E
L
I
K
S
A
N
L
G
K
S
E
Site 4
S36
K
S
A
N
L
G
K
S
E
F
D
P
S
E
S
Site 5
S41
G
K
S
E
F
D
P
S
E
S
F
S
P
D
L
Site 6
S43
S
E
F
D
P
S
E
S
F
S
P
D
L
F
V
Site 7
Y72
S
E
D
C
I
Q
M
Y
F
K
V
K
A
P
I
Site 8
S98
A
Q
M
C
A
P
K
S
A
E
N
L
E
E
F
Site 9
Y125
F
A
K
G
E
P
R
Y
Y
F
L
V
Y
N
A
Site 10
Y126
A
K
G
E
P
R
Y
Y
F
L
V
Y
N
A
S
Site 11
Y148
R
P
F
L
K
P
G
Y
R
H
H
L
I
P
S
Site 12
S164
S
Q
I
I
N
V
L
S
Q
T
E
E
E
D
K
Site 13
S199
E
E
A
A
R
F
C
S
T
A
A
P
F
I
K
Site 14
S207
T
A
A
P
F
I
K
S
H
V
P
Q
K
Y
R
Site 15
Y213
K
S
H
V
P
Q
K
Y
R
Q
I
F
S
V
M
Site 16
S238
L
K
E
E
K
K
N
S
I
S
L
S
V
T
F
Site 17
S240
E
E
K
K
N
S
I
S
L
S
V
T
F
Y
I
Site 18
S242
K
K
N
S
I
S
L
S
V
T
F
Y
I
N
M
Site 19
S264
N
D
L
P
G
D
I
S
V
I
L
R
K
A
Y
Site 20
Y271
S
V
I
L
R
K
A
Y
R
H
L
G
H
Y
N
Site 21
Y277
A
Y
R
H
L
G
H
Y
N
H
Q
R
F
P
S
Site 22
S284
Y
N
H
Q
R
F
P
S
I
S
E
E
K
M
L
Site 23
S286
H
Q
R
F
P
S
I
S
E
E
K
M
L
L
L
Site 24
S314
E
I
S
S
A
C
L
S
D
L
K
K
M
E
S
Site 25
S321
S
D
L
K
K
M
E
S
K
D
P
G
K
L
I
Site 26
S344
S
E
A
L
R
L
E
S
K
M
K
V
Y
N
R
Site 27
T422
E
K
L
D
S
L
M
T
L
L
R
C
Q
V
H
Site 28
T446
E
D
R
L
E
P
A
T
E
H
L
R
K
A
A
Site 29
S457
R
K
A
A
R
L
D
S
L
G
L
Y
R
D
R
Site 30
Y461
R
L
D
S
L
G
L
Y
R
D
R
I
Q
M
A
Site 31
S469
R
D
R
I
Q
M
A
S
T
R
L
R
L
C
T
Site 32
T476
S
T
R
L
R
L
C
T
T
L
Y
Q
A
P
E
Site 33
T477
T
R
L
R
L
C
T
T
L
Y
Q
A
P
E
R
Site 34
Y479
L
R
L
C
T
T
L
Y
Q
A
P
E
R
A
E
Site 35
T500
V
E
Q
A
K
K
A
T
P
K
D
S
V
R
K
Site 36
S504
K
K
A
T
P
K
D
S
V
R
K
K
R
A
L
Site 37
S537
S
E
N
E
A
K
V
S
T
G
K
N
R
G
R
Site 38
Y547
K
N
R
G
R
F
T
Y
L
C
A
K
A
W
H
Site 39
Y607
A
S
R
F
C
L
L
Y
D
N
V
K
V
K
K
Site 40
S629
K
K
R
G
R
D
G
S
V
Q
D
T
W
S
Q
Site 41
T633
R
D
G
S
V
Q
D
T
W
S
Q
P
E
V
V
Site 42
S635
G
S
V
Q
D
T
W
S
Q
P
E
V
V
L
Q
Site 43
S686
A
I
P
P
E
D
L
S
Q
H
P
A
G
Y
V
Site 44
Y692
L
S
Q
H
P
A
G
Y
V
P
E
P
P
E
V
Site 45
Y706
V
N
A
E
W
I
T
Y
R
T
W
I
E
S
L
Site 46
T708
A
E
W
I
T
Y
R
T
W
I
E
S
L
S
R
Site 47
S818
M
R
P
N
A
F
H
S
P
L
D
A
G
A
T
Site 48
T850
N
G
S
A
P
E
E
T
V
P
T
G
T
R
Q
Site 49
T853
A
P
E
E
T
V
P
T
G
T
R
Q
Q
L
I
Site 50
T880
Q
I
G
P
R
L
G
T
E
E
Q
G
T
N
E
Site 51
T885
L
G
T
E
E
Q
G
T
N
E
D
V
S
S
V
Site 52
S890
Q
G
T
N
E
D
V
S
S
V
T
R
V
L
V
Site 53
S925
A
Q
L
V
K
M
A
S
E
C
N
W
S
D
P
Site 54
S930
M
A
S
E
C
N
W
S
D
P
L
V
E
L
Q
Site 55
T938
D
P
L
V
E
L
Q
T
L
T
R
L
T
H
F
Site 56
T943
L
Q
T
L
T
R
L
T
H
F
A
H
A
A
R
Site 57
T955
A
A
R
D
H
E
T
T
M
A
C
A
H
R
A
Site 58
Y969
A
L
E
M
G
I
K
Y
L
K
K
F
G
P
E
Site 59
S1046
N
A
W
L
P
L
L
S
S
A
V
Y
R
K
K
Site 60
Y1050
P
L
L
S
S
A
V
Y
R
K
K
A
K
G
A
Site 61
T1068
L
I
G
I
I
N
K
T
E
A
R
K
Q
E
K
Site 62
T1078
R
K
Q
E
K
G
K
T
L
L
L
H
Q
W
P
Site 63
Y1098
G
G
G
T
T
E
G
Y
F
L
P
G
A
E
D
Site 64
S1166
A
K
L
G
Q
N
F
S
M
E
I
Q
K
F
K
Site 65
Y1179
F
K
A
E
S
E
D
Y
L
A
R
M
W
H
R
Site 66
S1191
W
H
R
L
A
L
N
S
P
S
V
S
G
E
L
Site 67
S1195
A
L
N
S
P
S
V
S
G
E
L
A
C
Y
N
Site 68
T1264
D
V
P
E
P
Q
P
T
P
D
G
E
Y
V
A
Site 69
Y1269
Q
P
T
P
D
G
E
Y
V
A
V
E
M
P
P
Site 70
S1278
A
V
E
M
P
P
R
S
P
V
S
E
A
E
E
Site 71
S1281
M
P
P
R
S
P
V
S
E
A
E
E
A
V
S
Site 72
S1288
S
E
A
E
E
A
V
S
L
E
Q
L
R
S
V
Site 73
S1294
V
S
L
E
Q
L
R
S
V
R
Q
L
E
A
L
Site 74
S1344
S
L
M
T
A
G
K
S
V
L
E
N
R
P
L
Site 75
T1354
E
N
R
P
L
A
A
T
S
S
H
L
L
L
P
Site 76
S1356
R
P
L
A
A
T
S
S
H
L
L
L
P
K
K
Site 77
S1370
K
E
K
E
N
E
R
S
K
E
K
E
K
E
R
Site 78
S1378
K
E
K
E
K
E
R
S
K
E
K
E
N
E
R
Site 79
S1386
K
E
K
E
N
E
R
S
K
E
K
D
K
E
K
Site 80
S1405
K
V
K
E
P
K
Q
S
Q
S
P
A
P
I
K
Site 81
S1407
K
E
P
K
Q
S
Q
S
P
A
P
I
K
Q
L
Site 82
S1420
Q
L
E
D
L
P
M
S
I
E
E
W
A
S
Y
Site 83
S1426
M
S
I
E
E
W
A
S
Y
S
C
P
E
E
V
Site 84
Y1427
S
I
E
E
W
A
S
Y
S
C
P
E
E
V
L
Site 85
S1428
I
E
E
W
A
S
Y
S
C
P
E
E
V
L
S
Site 86
S1435
S
C
P
E
E
V
L
S
V
L
K
Q
D
R
S
Site 87
S1442
S
V
L
K
Q
D
R
S
D
S
T
V
N
P
S
Site 88
S1444
L
K
Q
D
R
S
D
S
T
V
N
P
S
S
I
Site 89
T1445
K
Q
D
R
S
D
S
T
V
N
P
S
S
I
Q
Site 90
S1449
S
D
S
T
V
N
P
S
S
I
Q
K
P
T
Y
Site 91
S1450
D
S
T
V
N
P
S
S
I
Q
K
P
T
Y
S
Site 92
Y1456
S
S
I
Q
K
P
T
Y
S
L
Y
F
L
D
H
Site 93
S1457
S
I
Q
K
P
T
Y
S
L
Y
F
L
D
H
L
Site 94
Y1459
Q
K
P
T
Y
S
L
Y
F
L
D
H
L
V
K
Site 95
S1498
V
V
G
S
K
G
L
S
D
L
Y
H
L
R
W
Site 96
Y1501
S
K
G
L
S
D
L
Y
H
L
R
W
V
Q
L
Site 97
S1512
W
V
Q
L
L
F
R
S
V
I
S
P
K
Q
N
Site 98
S1515
L
L
F
R
S
V
I
S
P
K
Q
N
K
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation