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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAMD4B
Full Name:
Protein Smaug homolog 2
Alias:
FLJ10211; MGC99832; SAM4B; Smaug B; SMGB; Sterile alpha motif domain containing 4B
Type:
Uncharacterized protein
Mass (Da):
75483
Number AA:
694
UniProt ID:
Q5PRF9
International Prot ID:
IPI00791720
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
L
S
L
L
K
R
V
T
R
T
Q
A
R
F
L
Site 2
T36
L
L
K
R
V
T
R
T
Q
A
R
F
L
Q
L
Site 3
S60
N
D
I
H
L
L
E
S
E
A
N
S
A
A
I
Site 4
S69
A
N
S
A
A
I
V
S
Q
W
Q
Q
E
S
K
Site 5
S81
E
S
K
E
K
V
V
S
L
L
L
S
H
L
P
Site 6
T95
P
L
L
Q
P
G
N
T
E
A
K
S
E
Y
M
Site 7
S99
P
G
N
T
E
A
K
S
E
Y
M
R
L
L
Q
Site 8
Y101
N
T
E
A
K
S
E
Y
M
R
L
L
Q
K
V
Site 9
S122
S
N
A
F
I
E
E
S
R
Q
L
L
S
Y
A
Site 10
S127
E
E
S
R
Q
L
L
S
Y
A
L
I
H
P
A
Site 11
Y128
E
S
R
Q
L
L
S
Y
A
L
I
H
P
A
T
Site 12
S156
H
L
E
E
R
L
A
S
G
F
R
S
R
P
E
Site 13
S160
R
L
A
S
G
F
R
S
R
P
E
P
S
Y
H
Site 14
S165
F
R
S
R
P
E
P
S
Y
H
S
R
Q
G
S
Site 15
Y166
R
S
R
P
E
P
S
Y
H
S
R
Q
G
S
D
Site 16
S168
R
P
E
P
S
Y
H
S
R
Q
G
S
D
E
W
Site 17
S172
S
Y
H
S
R
Q
G
S
D
E
W
G
G
P
A
Site 18
S206
G
H
V
P
F
H
P
S
S
S
V
P
P
A
I
Site 19
S207
H
V
P
F
H
P
S
S
S
V
P
P
A
I
N
Site 20
S208
V
P
F
H
P
S
S
S
V
P
P
A
I
N
S
Site 21
S215
S
V
P
P
A
I
N
S
I
G
S
N
A
N
T
Site 22
S218
P
A
I
N
S
I
G
S
N
A
N
T
G
L
P
Site 23
T222
S
I
G
S
N
A
N
T
G
L
P
C
Q
I
H
Site 24
S231
L
P
C
Q
I
H
P
S
P
L
K
R
S
M
S
Site 25
S236
H
P
S
P
L
K
R
S
M
S
L
I
P
T
S
Site 26
S238
S
P
L
K
R
S
M
S
L
I
P
T
S
P
Q
Site 27
T242
R
S
M
S
L
I
P
T
S
P
Q
V
P
G
E
Site 28
S243
S
M
S
L
I
P
T
S
P
Q
V
P
G
E
W
Site 29
S252
Q
V
P
G
E
W
P
S
P
E
E
L
G
A
R
Site 30
T264
G
A
R
A
A
F
T
T
P
D
H
A
P
L
S
Site 31
S271
T
P
D
H
A
P
L
S
P
Q
S
S
V
A
S
Site 32
S274
H
A
P
L
S
P
Q
S
S
V
A
S
S
G
S
Site 33
S275
A
P
L
S
P
Q
S
S
V
A
S
S
G
S
E
Site 34
S278
S
P
Q
S
S
V
A
S
S
G
S
E
Q
T
E
Site 35
S279
P
Q
S
S
V
A
S
S
G
S
E
Q
T
E
E
Site 36
S281
S
S
V
A
S
S
G
S
E
Q
T
E
E
Q
G
Site 37
S289
E
Q
T
E
E
Q
G
S
S
R
N
T
F
Q
E
Site 38
S290
Q
T
E
E
Q
G
S
S
R
N
T
F
Q
E
D
Site 39
T293
E
Q
G
S
S
R
N
T
F
Q
E
D
G
S
G
Site 40
S306
S
G
M
K
D
V
P
S
W
L
K
S
L
R
L
Site 41
S310
D
V
P
S
W
L
K
S
L
R
L
H
K
Y
A
Site 42
Y316
K
S
L
R
L
H
K
Y
A
A
L
F
S
Q
M
Site 43
T330
M
S
Y
E
E
M
M
T
L
T
E
Q
H
L
E
Site 44
S338
L
T
E
Q
H
L
E
S
Q
N
V
T
K
G
A
Site 45
S352
A
R
H
K
I
A
L
S
I
Q
K
L
R
E
R
Site 46
S361
Q
K
L
R
E
R
Q
S
V
L
K
S
L
E
K
Site 47
S365
E
R
Q
S
V
L
K
S
L
E
K
D
V
L
E
Site 48
T405
Q
A
T
V
A
A
A
T
T
T
P
T
A
K
D
Site 49
T406
A
T
V
A
A
A
T
T
T
P
T
A
K
D
G
Site 50
T407
T
V
A
A
A
T
T
T
P
T
A
K
D
G
A
Site 51
T432
P
P
L
A
H
P
G
T
D
K
G
T
E
A
K
Site 52
T436
H
P
G
T
D
K
G
T
E
A
K
D
P
P
A
Site 53
Y447
D
P
P
A
V
E
N
Y
P
P
P
P
A
P
A
Site 54
S473
V
A
D
G
D
I
P
S
Q
F
T
R
V
M
G
Site 55
T497
R
P
D
E
E
N
I
T
S
Y
L
Q
L
I
E
Site 56
S498
P
D
E
E
N
I
T
S
Y
L
Q
L
I
E
K
Site 57
Y499
D
E
E
N
I
T
S
Y
L
Q
L
I
E
K
C
Site 58
T508
Q
L
I
E
K
C
L
T
H
E
A
F
T
E
T
Site 59
S522
T
Q
K
K
R
L
L
S
W
K
Q
Q
V
L
K
Site 60
Y545
A
A
L
E
M
Q
N
Y
R
Q
Q
K
G
W
A
Site 61
S555
Q
K
G
W
A
F
G
S
N
S
L
P
I
A
G
Site 62
S557
G
W
A
F
G
S
N
S
L
P
I
A
G
S
V
Site 63
S563
N
S
L
P
I
A
G
S
V
G
M
G
V
A
R
Site 64
T572
G
M
G
V
A
R
R
T
Q
R
Q
F
P
M
P
Site 65
S592
P
G
R
M
G
L
L
S
P
S
G
I
G
G
V
Site 66
S600
P
S
G
I
G
G
V
S
P
R
H
A
L
T
S
Site 67
T606
V
S
P
R
H
A
L
T
S
P
S
L
G
G
Q
Site 68
S607
S
P
R
H
A
L
T
S
P
S
L
G
G
Q
G
Site 69
S609
R
H
A
L
T
S
P
S
L
G
G
Q
G
R
Q
Site 70
S626
W
F
A
N
P
G
G
S
N
S
M
P
S
Q
S
Site 71
S628
A
N
P
G
G
S
N
S
M
P
S
Q
S
R
S
Site 72
S631
G
G
S
N
S
M
P
S
Q
S
R
S
S
V
Q
Site 73
S633
S
N
S
M
P
S
Q
S
R
S
S
V
Q
R
T
Site 74
S635
S
M
P
S
Q
S
R
S
S
V
Q
R
T
H
S
Site 75
S636
M
P
S
Q
S
R
S
S
V
Q
R
T
H
S
L
Site 76
T640
S
R
S
S
V
Q
R
T
H
S
L
P
V
H
S
Site 77
S642
S
S
V
Q
R
T
H
S
L
P
V
H
S
S
P
Site 78
S674
E
I
N
P
T
L
E
S
L
C
L
S
M
T
E
Site 79
T680
E
S
L
C
L
S
M
T
E
H
A
L
G
D
G
Site 80
T688
E
H
A
L
G
D
G
T
D
K
T
S
T
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation