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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF569
Full Name:
Zinc finger protein 569
Alias:
Zap1; Zn569; Znf; Znf569
Type:
Intracellular, Nucleus protein
Mass (Da):
79583
Number AA:
686
UniProt ID:
Q5MCW4
International Prot ID:
IPI00394985
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
T
E
S
Q
G
T
V
T
F
K
D
V
A
Site 2
T9
T
E
S
Q
G
T
V
T
F
K
D
V
A
I
D
Site 3
T18
K
D
V
A
I
D
F
T
Q
E
E
W
K
R
L
Site 4
Y33
D
P
A
Q
R
K
L
Y
R
N
V
M
L
E
N
Site 5
Y41
R
N
V
M
L
E
N
Y
N
N
L
I
T
V
G
Site 6
Y49
N
N
L
I
T
V
G
Y
P
F
T
K
P
D
V
Site 7
T108
V
K
F
Q
K
T
L
T
E
E
K
G
N
E
C
Site 8
S127
A
N
V
F
P
L
N
S
D
F
F
P
S
R
H
Site 9
Y137
F
P
S
R
H
N
L
Y
E
Y
D
L
F
G
K
Site 10
Y139
S
R
H
N
L
Y
E
Y
D
L
F
G
K
C
L
Site 11
Y167
M
R
K
E
H
C
E
Y
N
E
P
V
K
S
Y
Site 12
S173
E
Y
N
E
P
V
K
S
Y
G
N
S
S
S
H
Site 13
Y174
Y
N
E
P
V
K
S
Y
G
N
S
S
S
H
F
Site 14
S177
P
V
K
S
Y
G
N
S
S
S
H
F
V
I
T
Site 15
S179
K
S
Y
G
N
S
S
S
H
F
V
I
T
P
F
Site 16
T184
S
S
S
H
F
V
I
T
P
F
K
C
N
H
C
Site 17
T198
C
G
K
G
F
N
Q
T
L
D
L
I
R
H
L
Site 18
T209
I
R
H
L
R
I
H
T
G
E
K
P
Y
E
C
Site 19
S217
G
E
K
P
Y
E
C
S
N
C
R
K
A
F
S
Site 20
Y242
I
H
S
R
E
Q
S
Y
K
C
N
E
C
G
K
Site 21
T265
I
R
H
Q
R
I
H
T
G
E
K
P
Y
A
C
Site 22
S278
A
C
K
E
C
E
K
S
F
S
Q
K
S
N
L
Site 23
S280
K
E
C
E
K
S
F
S
Q
K
S
N
L
I
D
Site 24
S283
E
K
S
F
S
Q
K
S
N
L
I
D
H
E
K
Site 25
T293
I
D
H
E
K
I
H
T
G
E
K
P
Y
E
C
Site 26
Y298
I
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 27
S308
N
E
C
G
K
A
F
S
Q
K
Q
S
L
I
A
Site 28
S312
K
A
F
S
Q
K
Q
S
L
I
A
H
Q
K
V
Site 29
T321
I
A
H
Q
K
V
H
T
G
E
K
P
Y
A
C
Site 30
Y326
V
H
T
G
E
K
P
Y
A
C
N
E
C
G
K
Site 31
S347
S
L
A
L
H
M
R
S
H
T
G
E
K
P
Y
Site 32
T349
A
L
H
M
R
S
H
T
G
E
K
P
Y
K
C
Site 33
Y354
S
H
T
G
E
K
P
Y
K
C
D
K
C
G
K
Site 34
T377
I
I
H
V
R
I
H
T
G
E
K
P
Y
E
C
Site 35
S392
N
E
C
G
K
A
F
S
Q
S
S
A
L
T
V
Site 36
S395
G
K
A
F
S
Q
S
S
A
L
T
V
H
M
R
Site 37
T398
F
S
Q
S
S
A
L
T
V
H
M
R
S
H
T
Site 38
T405
T
V
H
M
R
S
H
T
G
E
K
P
Y
E
C
Site 39
Y410
S
H
T
G
E
K
P
Y
E
C
K
E
C
R
K
Site 40
Y438
I
H
T
R
E
K
P
Y
E
C
N
E
C
G
K
Site 41
S451
G
K
A
F
I
Q
M
S
N
L
V
R
H
Q
R
Site 42
T461
V
R
H
Q
R
I
H
T
G
E
K
P
Y
I
C
Site 43
Y466
I
H
T
G
E
K
P
Y
I
C
K
E
C
G
K
Site 44
S476
K
E
C
G
K
A
F
S
Q
K
S
N
L
I
A
Site 45
S479
G
K
A
F
S
Q
K
S
N
L
I
A
H
E
K
Site 46
S489
I
A
H
E
K
I
H
S
G
E
K
P
Y
E
C
Site 47
Y494
I
H
S
G
E
K
P
Y
E
C
N
E
C
G
K
Site 48
T517
I
T
H
Q
K
V
H
T
G
E
K
P
Y
D
C
Site 49
Y522
V
H
T
G
E
K
P
Y
D
C
N
E
C
G
K
Site 50
T538
F
S
Q
I
A
S
L
T
L
H
L
R
S
H
T
Site 51
S543
S
L
T
L
H
L
R
S
H
T
G
E
K
P
Y
Site 52
T545
T
L
H
L
R
S
H
T
G
E
K
P
Y
E
C
Site 53
Y550
S
H
T
G
E
K
P
Y
E
C
D
K
C
G
K
Site 54
S560
D
K
C
G
K
A
F
S
Q
C
S
L
L
N
L
Site 55
S563
G
K
A
F
S
Q
C
S
L
L
N
L
H
M
R
Site 56
S571
L
L
N
L
H
M
R
S
H
T
G
E
K
P
Y
Site 57
T573
N
L
H
M
R
S
H
T
G
E
K
P
Y
V
C
Site 58
Y578
S
H
T
G
E
K
P
Y
V
C
N
E
C
G
K
Site 59
S588
N
E
C
G
K
A
F
S
Q
R
T
S
L
I
V
Site 60
S592
K
A
F
S
Q
R
T
S
L
I
V
H
M
R
G
Site 61
T601
I
V
H
M
R
G
H
T
G
E
K
P
Y
E
C
Site 62
Y606
G
H
T
G
E
K
P
Y
E
C
N
K
C
G
K
Site 63
S616
N
K
C
G
K
A
F
S
Q
S
S
S
L
T
I
Site 64
S620
K
A
F
S
Q
S
S
S
L
T
I
H
I
R
G
Site 65
T622
F
S
Q
S
S
S
L
T
I
H
I
R
G
H
T
Site 66
T629
T
I
H
I
R
G
H
T
G
E
K
P
F
D
C
Site 67
S637
G
E
K
P
F
D
C
S
K
C
G
K
A
F
S
Site 68
S644
S
K
C
G
K
A
F
S
Q
I
S
S
L
T
L
Site 69
S648
K
A
F
S
Q
I
S
S
L
T
L
H
M
R
K
Site 70
T650
F
S
Q
I
S
S
L
T
L
H
M
R
K
H
T
Site 71
T657
T
L
H
M
R
K
H
T
G
E
K
P
Y
H
C
Site 72
Y662
K
H
T
G
E
K
P
Y
H
C
I
E
C
G
K
Site 73
S672
I
E
C
G
K
A
F
S
Q
K
S
H
L
V
R
Site 74
S675
G
K
A
F
S
Q
K
S
H
L
V
R
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation