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Updated November 2019
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Protein Info
Short Name:
CYTSB
Full Name:
Cytospin-B
Alias:
Cytokinesis and spindle organization B; Cytospin B; FLJ36955; HCMOGT-1; NSP; Nuclear structure protein 5; SPEC1; Spectrin domain with coiled-coils 1; Sperm antigen HCMOGT 1; Sperm antigen HCMOGT-1; Sperm antigen with calponin homology and coiled-coil domains 1; Sperm antigen with calponin homology and coiled-coil domains 1: Nuclear structure protein 5: Sperm antigen HCMOGT-1: Sperm antigen with calponin homology and coiled-coil domains 1: Nuclear structure protein 5: Sperm antigen HCMOGT-1: Sperm antigen with calponin homology and coiled-coil domains 1: Nuclear structure protein 5: Sperm antigen HCMOGT-1: Sperm antigen with calponin homology and coiled-coil domains 1: Nuclear structure protein 5: Sperm antigen HCMOGT-1: Sperm antigen with calponin homology and coiled-coil domains 1: Nuclear structure protein 5: Sperm antigen HCMOGT-1; Structure protein NSP5a3a; Structure protein NSP5a3b; Structure protein NSP5b3a; Structure protein NSP5b3b
Type:
Unknown function
Mass (Da):
118585
Number AA:
1068
UniProt ID:
Q5M775
International Prot ID:
IPI00291032
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
V
R
P
L
P
A
A
S
S
G
M
K
S
S
K
Site 2
S30
R
P
L
P
A
A
S
S
G
M
K
S
S
K
S
Site 3
S34
A
A
S
S
G
M
K
S
S
K
S
S
T
S
L
Site 4
S35
A
S
S
G
M
K
S
S
K
S
S
T
S
L
A
Site 5
S37
S
G
M
K
S
S
K
S
S
T
S
L
A
F
E
Site 6
S38
G
M
K
S
S
K
S
S
T
S
L
A
F
E
S
Site 7
T39
M
K
S
S
K
S
S
T
S
L
A
F
E
S
R
Site 8
S40
K
S
S
K
S
S
T
S
L
A
F
E
S
R
L
Site 9
S45
S
T
S
L
A
F
E
S
R
L
S
R
L
K
R
Site 10
S48
L
A
F
E
S
R
L
S
R
L
K
R
A
S
S
Site 11
S54
L
S
R
L
K
R
A
S
S
E
D
T
L
N
K
Site 12
S55
S
R
L
K
R
A
S
S
E
D
T
L
N
K
P
Site 13
T58
K
R
A
S
S
E
D
T
L
N
K
P
G
S
T
Site 14
S64
D
T
L
N
K
P
G
S
T
A
A
S
G
V
V
Site 15
S68
K
P
G
S
T
A
A
S
G
V
V
R
L
K
K
Site 16
S83
T
A
T
A
G
A
I
S
E
L
T
E
S
R
L
Site 17
T86
A
G
A
I
S
E
L
T
E
S
R
L
R
S
G
Site 18
S88
A
I
S
E
L
T
E
S
R
L
R
S
G
T
G
Site 19
S92
L
T
E
S
R
L
R
S
G
T
G
A
F
T
T
Site 20
T94
E
S
R
L
R
S
G
T
G
A
F
T
T
T
K
Site 21
T99
S
G
T
G
A
F
T
T
T
K
R
T
G
I
P
Site 22
S112
I
P
A
P
R
E
F
S
V
T
V
S
R
E
R
Site 23
T114
A
P
R
E
F
S
V
T
V
S
R
E
R
S
V
Site 24
S116
R
E
F
S
V
T
V
S
R
E
R
S
V
P
R
Site 25
S120
V
T
V
S
R
E
R
S
V
P
R
G
P
S
N
Site 26
S126
R
S
V
P
R
G
P
S
N
P
R
K
S
V
S
Site 27
S131
G
P
S
N
P
R
K
S
V
S
S
P
T
S
S
Site 28
S133
S
N
P
R
K
S
V
S
S
P
T
S
S
N
T
Site 29
S134
N
P
R
K
S
V
S
S
P
T
S
S
N
T
P
Site 30
S137
K
S
V
S
S
P
T
S
S
N
T
P
T
P
T
Site 31
S138
S
V
S
S
P
T
S
S
N
T
P
T
P
T
K
Site 32
T140
S
S
P
T
S
S
N
T
P
T
P
T
K
H
L
Site 33
T142
P
T
S
S
N
T
P
T
P
T
K
H
L
R
T
Site 34
T149
T
P
T
K
H
L
R
T
P
S
T
K
P
K
Q
Site 35
S151
T
K
H
L
R
T
P
S
T
K
P
K
Q
E
N
Site 36
T152
K
H
L
R
T
P
S
T
K
P
K
Q
E
N
E
Site 37
S168
G
E
K
A
A
L
E
S
Q
V
R
E
L
L
A
Site 38
S182
A
E
A
K
A
K
D
S
E
I
N
R
L
R
S
Site 39
S189
S
E
I
N
R
L
R
S
E
L
K
K
Y
K
E
Site 40
Y194
L
R
S
E
L
K
K
Y
K
E
K
R
T
L
N
Site 41
T205
R
T
L
N
A
E
G
T
D
A
L
G
P
N
V
Site 42
T215
L
G
P
N
V
D
G
T
S
V
S
P
G
D
T
Site 43
S216
G
P
N
V
D
G
T
S
V
S
P
G
D
T
E
Site 44
S218
N
V
D
G
T
S
V
S
P
G
D
T
E
P
M
Site 45
T222
T
S
V
S
P
G
D
T
E
P
M
I
R
A
L
Site 46
S241
K
N
F
Q
K
E
L
S
D
L
E
E
E
N
R
Site 47
Y256
V
L
K
E
K
L
I
Y
L
E
H
S
P
N
S
Site 48
S260
K
L
I
Y
L
E
H
S
P
N
S
E
G
A
A
Site 49
S263
Y
L
E
H
S
P
N
S
E
G
A
A
S
H
T
Site 50
S268
P
N
S
E
G
A
A
S
H
T
G
D
S
S
C
Site 51
T270
S
E
G
A
A
S
H
T
G
D
S
S
C
P
T
Site 52
S273
A
A
S
H
T
G
D
S
S
C
P
T
S
I
T
Site 53
S274
A
S
H
T
G
D
S
S
C
P
T
S
I
T
Q
Site 54
T277
T
G
D
S
S
C
P
T
S
I
T
Q
E
S
S
Site 55
S278
G
D
S
S
C
P
T
S
I
T
Q
E
S
S
F
Site 56
T280
S
S
C
P
T
S
I
T
Q
E
S
S
F
G
S
Site 57
S283
P
T
S
I
T
Q
E
S
S
F
G
S
P
T
G
Site 58
S284
T
S
I
T
Q
E
S
S
F
G
S
P
T
G
N
Site 59
S287
T
Q
E
S
S
F
G
S
P
T
G
N
Q
M
S
Site 60
T289
E
S
S
F
G
S
P
T
G
N
Q
M
S
S
D
Site 61
S294
S
P
T
G
N
Q
M
S
S
D
I
D
E
Y
K
Site 62
S295
P
T
G
N
Q
M
S
S
D
I
D
E
Y
K
K
Site 63
Y300
M
S
S
D
I
D
E
Y
K
K
N
I
H
G
N
Site 64
T311
I
H
G
N
A
L
R
T
S
G
S
S
S
S
D
Site 65
S312
H
G
N
A
L
R
T
S
G
S
S
S
S
D
V
Site 66
S314
N
A
L
R
T
S
G
S
S
S
S
D
V
T
K
Site 67
S315
A
L
R
T
S
G
S
S
S
S
D
V
T
K
A
Site 68
S316
L
R
T
S
G
S
S
S
S
D
V
T
K
A
S
Site 69
S317
R
T
S
G
S
S
S
S
D
V
T
K
A
S
L
Site 70
T320
G
S
S
S
S
D
V
T
K
A
S
L
S
P
D
Site 71
S323
S
S
D
V
T
K
A
S
L
S
P
D
A
S
D
Site 72
S325
D
V
T
K
A
S
L
S
P
D
A
S
D
F
E
Site 73
S329
A
S
L
S
P
D
A
S
D
F
E
H
I
T
A
Site 74
T338
F
E
H
I
T
A
E
T
P
S
R
P
L
S
S
Site 75
S340
H
I
T
A
E
T
P
S
R
P
L
S
S
T
S
Site 76
S344
E
T
P
S
R
P
L
S
S
T
S
N
P
F
K
Site 77
S345
T
P
S
R
P
L
S
S
T
S
N
P
F
K
S
Site 78
T346
P
S
R
P
L
S
S
T
S
N
P
F
K
S
S
Site 79
S347
S
R
P
L
S
S
T
S
N
P
F
K
S
S
K
Site 80
S352
S
T
S
N
P
F
K
S
S
K
C
S
T
A
G
Site 81
S353
T
S
N
P
F
K
S
S
K
C
S
T
A
G
S
Site 82
S356
P
F
K
S
S
K
C
S
T
A
G
S
S
P
N
Site 83
T357
F
K
S
S
K
C
S
T
A
G
S
S
P
N
S
Site 84
S360
S
K
C
S
T
A
G
S
S
P
N
S
V
S
E
Site 85
S361
K
C
S
T
A
G
S
S
P
N
S
V
S
E
L
Site 86
S364
T
A
G
S
S
P
N
S
V
S
E
L
S
L
A
Site 87
S366
G
S
S
P
N
S
V
S
E
L
S
L
A
S
L
Site 88
S369
P
N
S
V
S
E
L
S
L
A
S
L
T
E
K
Site 89
S372
V
S
E
L
S
L
A
S
L
T
E
K
I
Q
K
Site 90
S386
K
M
E
E
N
H
H
S
T
A
E
E
L
Q
A
Site 91
T394
T
A
E
E
L
Q
A
T
L
Q
E
L
S
D
Q
Site 92
S399
Q
A
T
L
Q
E
L
S
D
Q
Q
Q
M
V
Q
Site 93
T420
E
K
L
V
D
E
K
T
I
L
E
T
S
F
H
Site 94
S425
E
K
T
I
L
E
T
S
F
H
Q
H
R
E
R
Site 95
S437
R
E
R
A
E
Q
L
S
Q
E
N
E
K
L
M
Site 96
T458
V
K
N
E
E
P
T
T
Q
E
G
K
I
I
E
Site 97
T471
I
E
L
E
Q
K
C
T
G
I
L
E
Q
G
R
Site 98
S494
I
Q
Q
Q
L
T
C
S
L
R
K
V
E
E
E
Site 99
T543
T
L
E
E
C
R
V
T
L
E
G
L
K
M
E
Site 100
S553
G
L
K
M
E
N
G
S
L
K
S
H
L
Q
G
Site 101
S577
A
V
E
Q
T
A
E
S
C
E
V
Q
E
M
L
Site 102
S597
E
K
D
L
L
E
L
S
C
N
E
L
R
Q
E
Site 103
Y626
L
A
K
V
E
K
D
Y
S
Y
L
K
E
I
C
Site 104
S627
A
K
V
E
K
D
Y
S
Y
L
K
E
I
C
D
Site 105
Y628
K
V
E
K
D
Y
S
Y
L
K
E
I
C
D
H
Site 106
S641
D
H
Q
A
E
Q
L
S
R
T
S
L
K
L
Q
Site 107
S644
A
E
Q
L
S
R
T
S
L
K
L
Q
E
K
A
Site 108
S652
L
K
L
Q
E
K
A
S
E
S
D
A
E
I
K
Site 109
S654
L
Q
E
K
A
S
E
S
D
A
E
I
K
D
M
Site 110
S687
L
H
N
N
Q
L
I
S
E
L
E
S
S
V
I
Site 111
S691
Q
L
I
S
E
L
E
S
S
V
I
K
L
E
E
Site 112
S692
L
I
S
E
L
E
S
S
V
I
K
L
E
E
Q
Site 113
S701
I
K
L
E
E
Q
K
S
D
L
E
R
Q
L
K
Site 114
T748
E
A
Q
Q
E
L
R
T
V
K
R
K
L
L
E
Site 115
T778
Q
G
H
G
R
V
V
T
S
R
A
A
P
P
P
Site 116
S792
P
V
D
E
E
P
E
S
S
E
V
D
A
A
G
Site 117
S793
V
D
E
E
P
E
S
S
E
V
D
A
A
G
R
Site 118
S807
R
W
P
G
V
C
V
S
R
T
S
P
T
P
P
Site 119
T809
P
G
V
C
V
S
R
T
S
P
T
P
P
E
S
Site 120
S810
G
V
C
V
S
R
T
S
P
T
P
P
E
S
A
Site 121
T812
C
V
S
R
T
S
P
T
P
P
E
S
A
T
T
Site 122
S816
T
S
P
T
P
P
E
S
A
T
T
V
K
S
L
Site 123
T818
P
T
P
P
E
S
A
T
T
V
K
S
L
I
K
Site 124
T819
T
P
P
E
S
A
T
T
V
K
S
L
I
K
S
Site 125
S822
E
S
A
T
T
V
K
S
L
I
K
S
F
D
L
Site 126
S826
T
V
K
S
L
I
K
S
F
D
L
G
R
P
G
Site 127
S840
G
G
A
G
Q
N
I
S
V
H
K
T
P
R
S
Site 128
T844
Q
N
I
S
V
H
K
T
P
R
S
P
L
S
G
Site 129
S847
S
V
H
K
T
P
R
S
P
L
S
G
I
P
V
Site 130
S850
K
T
P
R
S
P
L
S
G
I
P
V
R
T
A
Site 131
S863
T
A
P
A
A
A
V
S
P
M
Q
R
H
S
T
Site 132
S869
V
S
P
M
Q
R
H
S
T
Y
S
S
V
R
P
Site 133
T870
S
P
M
Q
R
H
S
T
Y
S
S
V
R
P
A
Site 134
Y871
P
M
Q
R
H
S
T
Y
S
S
V
R
P
A
S
Site 135
S872
M
Q
R
H
S
T
Y
S
S
V
R
P
A
S
R
Site 136
S873
Q
R
H
S
T
Y
S
S
V
R
P
A
S
R
G
Site 137
S878
Y
S
S
V
R
P
A
S
R
G
V
T
Q
R
L
Site 138
T882
R
P
A
S
R
G
V
T
Q
R
L
D
L
P
D
Site 139
S893
D
L
P
D
L
P
L
S
D
I
L
K
G
R
T
Site 140
T902
I
L
K
G
R
T
E
T
L
K
P
D
P
H
L
Site 141
S912
P
D
P
H
L
R
K
S
P
S
L
E
S
L
S
Site 142
S914
P
H
L
R
K
S
P
S
L
E
S
L
S
R
P
Site 143
S917
R
K
S
P
S
L
E
S
L
S
R
P
P
S
L
Site 144
S919
S
P
S
L
E
S
L
S
R
P
P
S
L
G
F
Site 145
S923
E
S
L
S
R
P
P
S
L
G
F
G
D
T
R
Site 146
T929
P
S
L
G
F
G
D
T
R
L
L
S
A
S
T
Site 147
S933
F
G
D
T
R
L
L
S
A
S
T
R
A
W
K
Site 148
S935
D
T
R
L
L
S
A
S
T
R
A
W
K
P
Q
Site 149
S943
T
R
A
W
K
P
Q
S
K
L
S
V
E
R
K
Site 150
S946
W
K
P
Q
S
K
L
S
V
E
R
K
D
P
L
Site 151
Y960
L
A
A
L
A
R
E
Y
G
G
S
K
R
N
A
Site 152
S963
L
A
R
E
Y
G
G
S
K
R
N
A
L
L
K
Site 153
S988
N
I
D
I
T
N
F
S
S
S
W
S
D
G
L
Site 154
S990
D
I
T
N
F
S
S
S
W
S
D
G
L
A
F
Site 155
S992
T
N
F
S
S
S
W
S
D
G
L
A
F
C
A
Site 156
S1016
I
P
Y
Q
E
L
N
S
Q
E
K
K
R
N
L
Site 157
S1042
I
K
P
S
L
E
L
S
E
M
L
Y
T
D
R
Site 158
Y1046
L
E
L
S
E
M
L
Y
T
D
R
P
D
W
Q
Site 159
T1047
E
L
S
E
M
L
Y
T
D
R
P
D
W
Q
S
Site 160
Y1058
D
W
Q
S
V
M
Q
Y
V
A
Q
I
Y
K
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation