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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RP5-1077B9.4
Full Name:
Migration and invasion-inhibitory protein
Alias:
FLJ12438; FLJ38609; Iip45; Invasion inhibitory protein 45
Type:
Mass (Da):
42825
Number AA:
388
UniProt ID:
Q5JXC2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
G
Q
D
A
V
R
R
S
V
A
R
A
A
S
E
Site 2
S37
R
S
V
A
R
A
A
S
E
S
S
L
E
S
S
Site 3
S39
V
A
R
A
A
S
E
S
S
L
E
S
S
S
S
Site 4
S40
A
R
A
A
S
E
S
S
L
E
S
S
S
S
Y
Site 5
S43
A
S
E
S
S
L
E
S
S
S
S
Y
N
S
E
Site 6
S44
S
E
S
S
L
E
S
S
S
S
Y
N
S
E
T
Site 7
S45
E
S
S
L
E
S
S
S
S
Y
N
S
E
T
P
Site 8
S46
S
S
L
E
S
S
S
S
Y
N
S
E
T
P
S
Site 9
Y47
S
L
E
S
S
S
S
Y
N
S
E
T
P
S
T
Site 10
S49
E
S
S
S
S
Y
N
S
E
T
P
S
T
P
E
Site 11
T51
S
S
S
Y
N
S
E
T
P
S
T
P
E
T
S
Site 12
S53
S
Y
N
S
E
T
P
S
T
P
E
T
S
S
T
Site 13
T54
Y
N
S
E
T
P
S
T
P
E
T
S
S
T
S
Site 14
T57
E
T
P
S
T
P
E
T
S
S
T
S
L
S
T
Site 15
S58
T
P
S
T
P
E
T
S
S
T
S
L
S
T
S
Site 16
S59
P
S
T
P
E
T
S
S
T
S
L
S
T
S
C
Site 17
T60
S
T
P
E
T
S
S
T
S
L
S
T
S
C
P
Site 18
S61
T
P
E
T
S
S
T
S
L
S
T
S
C
P
R
Site 19
S63
E
T
S
S
T
S
L
S
T
S
C
P
R
G
R
Site 20
T64
T
S
S
T
S
L
S
T
S
C
P
R
G
R
S
Site 21
S65
S
S
T
S
L
S
T
S
C
P
R
G
R
S
S
Site 22
S71
T
S
C
P
R
G
R
S
S
V
W
G
P
P
D
Site 23
S72
S
C
P
R
G
R
S
S
V
W
G
P
P
D
A
Site 24
S90
D
L
R
D
V
A
R
S
G
V
A
S
L
P
P
Site 25
S105
A
K
C
Q
H
Q
E
S
L
G
R
P
R
P
H
Site 26
S113
L
G
R
P
R
P
H
S
A
P
S
L
G
T
S
Site 27
S116
P
R
P
H
S
A
P
S
L
G
T
S
S
L
R
Site 28
S120
S
A
P
S
L
G
T
S
S
L
R
D
P
E
P
Site 29
S121
A
P
S
L
G
T
S
S
L
R
D
P
E
P
S
Site 30
S128
S
L
R
D
P
E
P
S
G
R
L
G
D
P
G
Site 31
T141
P
G
P
Q
E
A
Q
T
P
R
S
I
L
A
Q
Site 32
S144
Q
E
A
Q
T
P
R
S
I
L
A
Q
Q
S
K
Site 33
S150
R
S
I
L
A
Q
Q
S
K
L
S
K
P
R
V
Site 34
S153
L
A
Q
Q
S
K
L
S
K
P
R
V
T
F
S
Site 35
T158
K
L
S
K
P
R
V
T
F
S
E
E
S
A
V
Site 36
S163
R
V
T
F
S
E
E
S
A
V
P
E
R
S
W
Site 37
S169
E
S
A
V
P
E
R
S
W
R
L
R
P
Y
L
Site 38
Y175
R
S
W
R
L
R
P
Y
L
G
Y
D
W
I
A
Site 39
Y178
R
L
R
P
Y
L
G
Y
D
W
I
A
G
S
L
Site 40
S184
G
Y
D
W
I
A
G
S
L
D
T
S
S
S
I
Site 41
S188
I
A
G
S
L
D
T
S
S
S
I
T
S
Q
P
Site 42
S189
A
G
S
L
D
T
S
S
S
I
T
S
Q
P
E
Site 43
S190
G
S
L
D
T
S
S
S
I
T
S
Q
P
E
A
Site 44
T192
L
D
T
S
S
S
I
T
S
Q
P
E
A
F
F
Site 45
S193
D
T
S
S
S
I
T
S
Q
P
E
A
F
F
S
Site 46
S200
S
Q
P
E
A
F
F
S
K
L
Q
E
F
R
E
Site 47
T208
K
L
Q
E
F
R
E
T
N
K
E
E
C
I
C
Site 48
S216
N
K
E
E
C
I
C
S
H
P
E
P
Q
L
P
Site 49
S228
Q
L
P
G
L
R
E
S
S
G
S
G
V
E
E
Site 50
S229
L
P
G
L
R
E
S
S
G
S
G
V
E
E
D
Site 51
S231
G
L
R
E
S
S
G
S
G
V
E
E
D
H
E
Site 52
Y241
E
E
D
H
E
C
V
Y
C
Y
R
V
N
R
R
Site 53
T258
P
V
P
V
D
P
G
T
P
C
R
L
C
R
T
Site 54
T265
T
P
C
R
L
C
R
T
P
R
D
Q
Q
G
P
Site 55
T274
R
D
Q
Q
G
P
G
T
L
A
Q
P
A
H
V
Site 56
S303
Y
H
I
H
R
R
K
S
F
D
A
S
D
T
L
Site 57
S307
R
R
K
S
F
D
A
S
D
T
L
A
L
P
R
Site 58
T309
K
S
F
D
A
S
D
T
L
A
L
P
R
H
C
Site 59
S327
W
D
I
F
P
P
K
S
E
K
S
S
A
P
R
Site 60
S331
P
P
K
S
E
K
S
S
A
P
R
N
L
D
L
Site 61
S340
P
R
N
L
D
L
W
S
S
V
S
A
E
A
Q
Site 62
S341
R
N
L
D
L
W
S
S
V
S
A
E
A
Q
H
Site 63
S343
L
D
L
W
S
S
V
S
A
E
A
Q
H
Q
K
Site 64
S352
E
A
Q
H
Q
K
L
S
G
T
S
S
P
F
H
Site 65
T354
Q
H
Q
K
L
S
G
T
S
S
P
F
H
P
A
Site 66
S356
Q
K
L
S
G
T
S
S
P
F
H
P
A
S
P
Site 67
S362
S
S
P
F
H
P
A
S
P
M
Q
M
L
P
P
Site 68
T370
P
M
Q
M
L
P
P
T
P
T
W
S
V
P
Q
Site 69
T372
Q
M
L
P
P
T
P
T
W
S
V
P
Q
V
P
Site 70
S374
L
P
P
T
P
T
W
S
V
P
Q
V
P
R
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation