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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCNT1
Full Name:
Potassium channel subfamily T member 1
Alias:
KCa4.1
Type:
Mass (Da):
138343
Number AA:
1230
UniProt ID:
Q5JUK3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
R
A
K
L
P
R
S
P
S
E
G
K
A
G
Site 2
S11
A
K
L
P
R
S
P
S
E
G
K
A
G
P
G
Site 3
S34
P
E
E
P
H
G
L
S
P
L
L
P
A
R
G
Site 4
S44
L
P
A
R
G
G
G
S
V
G
S
D
V
G
Q
Site 5
S47
R
G
G
G
S
V
G
S
D
V
G
Q
R
L
P
Site 6
S59
R
L
P
V
E
D
F
S
L
D
S
S
L
S
Q
Site 7
S62
V
E
D
F
S
L
D
S
S
L
S
Q
V
Q
V
Site 8
S63
E
D
F
S
L
D
S
S
L
S
Q
V
Q
V
E
Site 9
S65
F
S
L
D
S
S
L
S
Q
V
Q
V
E
F
Y
Site 10
Y72
S
Q
V
Q
V
E
F
Y
V
N
E
N
T
F
K
Site 11
T77
E
F
Y
V
N
E
N
T
F
K
E
R
L
K
L
Site 12
S92
F
F
I
K
N
Q
R
S
S
L
R
I
R
L
F
Site 13
S93
F
I
K
N
Q
R
S
S
L
R
I
R
L
F
N
Site 14
Y134
W
G
C
P
K
Q
N
Y
S
F
N
D
S
S
S
Site 15
S135
G
C
P
K
Q
N
Y
S
F
N
D
S
S
S
E
Site 16
S139
Q
N
Y
S
F
N
D
S
S
S
E
I
N
W
A
Site 17
S141
Y
S
F
N
D
S
S
S
E
I
N
W
A
P
I
Site 18
T244
F
H
R
A
I
L
R
T
Q
S
A
M
F
N
Q
Site 19
S281
E
R
A
G
E
N
L
S
L
L
T
S
F
Y
F
Site 20
T302
T
V
G
Y
G
D
V
T
P
K
I
W
P
S
Q
Site 21
Y332
L
Q
F
E
E
L
V
Y
L
W
M
E
R
Q
K
Site 22
S340
L
W
M
E
R
Q
K
S
G
G
N
Y
S
R
H
Site 23
Y344
R
Q
K
S
G
G
N
Y
S
R
H
R
A
Q
T
Site 24
S345
Q
K
S
G
G
N
Y
S
R
H
R
A
Q
T
E
Site 25
T351
Y
S
R
H
R
A
Q
T
E
K
H
V
V
L
C
Site 26
Y375
M
D
F
L
N
E
F
Y
A
H
P
R
L
Q
D
Site 27
S438
G
E
A
C
F
I
L
S
S
R
N
E
V
D
R
Site 28
S439
E
A
C
F
I
L
S
S
R
N
E
V
D
R
T
Site 29
T446
S
R
N
E
V
D
R
T
A
A
D
H
Q
T
I
Site 30
T452
R
T
A
A
D
H
Q
T
I
L
R
A
W
A
V
Site 31
S526
R
G
Q
E
G
Q
E
S
P
E
Q
W
Q
R
M
Site 32
Y534
P
E
Q
W
Q
R
M
Y
G
R
C
S
G
N
E
Site 33
Y543
R
C
S
G
N
E
V
Y
H
I
R
M
G
D
S
Site 34
Y556
D
S
K
F
F
R
E
Y
E
G
K
S
F
T
Y
Site 35
Y563
Y
E
G
K
S
F
T
Y
A
A
F
H
A
H
K
Site 36
S586
L
K
R
E
D
N
K
S
I
L
L
N
P
G
P
Site 37
T609
T
C
F
Y
I
N
I
T
K
E
E
N
S
A
F
Site 38
S630
K
R
K
K
R
A
F
S
G
Q
G
L
H
E
G
Site 39
T665
Q
G
T
E
H
R
P
T
Q
S
G
G
G
G
G
Site 40
S667
T
E
H
R
P
T
Q
S
G
G
G
G
G
G
S
Site 41
S674
S
G
G
G
G
G
G
S
K
L
A
L
P
T
E
Site 42
T680
G
S
K
L
A
L
P
T
E
N
G
S
G
S
R
Site 43
S684
A
L
P
T
E
N
G
S
G
S
R
R
P
S
I
Site 44
S686
P
T
E
N
G
S
G
S
R
R
P
S
I
A
P
Site 45
S690
G
S
G
S
R
R
P
S
I
A
P
V
L
E
L
Site 46
S710
L
L
P
C
D
L
L
S
D
Q
S
E
D
E
V
Site 47
S713
C
D
L
L
S
D
Q
S
E
D
E
V
T
P
S
Site 48
T718
D
Q
S
E
D
E
V
T
P
S
D
D
E
G
L
Site 49
S720
S
E
D
E
V
T
P
S
D
D
E
G
L
S
V
Site 50
S726
P
S
D
D
E
G
L
S
V
V
E
Y
V
K
G
Site 51
Y730
E
G
L
S
V
V
E
Y
V
K
G
Y
P
P
N
Site 52
Y734
V
V
E
Y
V
K
G
Y
P
P
N
S
P
Y
I
Site 53
S738
V
K
G
Y
P
P
N
S
P
Y
I
G
S
S
P
Site 54
Y740
G
Y
P
P
N
S
P
Y
I
G
S
S
P
T
L
Site 55
S743
P
N
S
P
Y
I
G
S
S
P
T
L
C
H
L
Site 56
S770
D
K
G
C
K
H
N
S
Y
E
D
A
K
A
Y
Site 57
Y771
K
G
C
K
H
N
S
Y
E
D
A
K
A
Y
G
Site 58
S787
K
N
K
L
I
I
V
S
A
E
T
A
G
N
G
Site 59
Y805
F
I
V
P
L
R
A
Y
Y
R
S
R
K
E
L
Site 60
Y806
I
V
P
L
R
A
Y
Y
R
S
R
K
E
L
N
Site 61
S808
P
L
R
A
Y
Y
R
S
R
K
E
L
N
P
I
Site 62
S843
M
V
Y
Y
M
E
G
S
V
D
N
L
D
S
L
Site 63
S871
V
D
K
E
S
T
M
S
A
E
E
D
Y
M
A
Site 64
Y876
T
M
S
A
E
E
D
Y
M
A
D
A
K
T
I
Site 65
T903
L
S
I
T
T
E
L
T
H
P
S
N
M
R
F
Site 66
S918
M
Q
F
R
A
K
D
S
Y
S
L
A
L
S
K
Site 67
Y919
Q
F
R
A
K
D
S
Y
S
L
A
L
S
K
L
Site 68
S920
F
R
A
K
D
S
Y
S
L
A
L
S
K
L
E
Site 69
S924
D
S
Y
S
L
A
L
S
K
L
E
K
R
E
R
Site 70
S935
K
R
E
R
E
N
G
S
N
L
A
F
M
F
R
Site 71
Y961
S
M
L
D
T
L
L
Y
Q
S
F
V
K
D
Y
Site 72
S985
G
L
D
T
T
P
G
S
G
Y
L
C
A
M
K
Site 73
Y987
D
T
T
P
G
S
G
Y
L
C
A
M
K
I
T
Site 74
T1002
E
G
D
L
W
I
R
T
Y
G
R
L
F
Q
K
Site 75
Y1003
G
D
L
W
I
R
T
Y
G
R
L
F
Q
K
L
Site 76
S1026
I
G
I
Y
R
T
E
S
H
V
F
S
T
S
E
Site 77
S1030
R
T
E
S
H
V
F
S
T
S
E
S
Q
I
S
Site 78
S1032
E
S
H
V
F
S
T
S
E
S
Q
I
S
V
N
Site 79
S1034
H
V
F
S
T
S
E
S
Q
I
S
V
N
V
E
Site 80
S1037
S
T
S
E
S
Q
I
S
V
N
V
E
D
C
E
Site 81
T1046
N
V
E
D
C
E
D
T
R
E
V
K
G
P
W
Site 82
S1055
E
V
K
G
P
W
G
S
R
A
G
T
G
G
S
Site 83
T1059
P
W
G
S
R
A
G
T
G
G
S
S
Q
G
R
Site 84
S1062
S
R
A
G
T
G
G
S
S
Q
G
R
H
T
G
Site 85
S1063
R
A
G
T
G
G
S
S
Q
G
R
H
T
G
G
Site 86
T1068
G
S
S
Q
G
R
H
T
G
G
G
D
P
A
E
Site 87
S1083
H
P
L
L
R
R
K
S
L
Q
W
A
R
R
L
Site 88
S1091
L
Q
W
A
R
R
L
S
R
K
A
P
K
Q
A
Site 89
S1108
A
A
A
A
E
W
I
S
Q
Q
R
L
S
L
Y
Site 90
S1113
W
I
S
Q
Q
R
L
S
L
Y
R
R
S
E
R
Site 91
Y1115
S
Q
Q
R
L
S
L
Y
R
R
S
E
R
Q
E
Site 92
S1118
R
L
S
L
Y
R
R
S
E
R
Q
E
L
S
E
Site 93
S1124
R
S
E
R
Q
E
L
S
E
L
V
K
N
R
M
Site 94
S1150
D
V
A
N
L
T
A
S
D
V
M
N
R
V
N
Site 95
Y1160
M
N
R
V
N
L
G
Y
L
Q
D
E
M
N
D
Site 96
T1171
E
M
N
D
H
Q
N
T
L
S
Y
V
L
I
N
Site 97
S1173
N
D
H
Q
N
T
L
S
Y
V
L
I
N
P
P
Site 98
Y1174
D
H
Q
N
T
L
S
Y
V
L
I
N
P
P
P
Site 99
T1183
L
I
N
P
P
P
D
T
R
L
E
P
S
D
I
Site 100
S1188
P
D
T
R
L
E
P
S
D
I
V
Y
L
I
R
Site 101
S1204
D
P
L
A
H
V
A
S
S
S
Q
S
R
K
S
Site 102
S1205
P
L
A
H
V
A
S
S
S
Q
S
R
K
S
S
Site 103
S1206
L
A
H
V
A
S
S
S
Q
S
R
K
S
S
C
Site 104
S1208
H
V
A
S
S
S
Q
S
R
K
S
S
C
S
H
Site 105
S1211
S
S
S
Q
S
R
K
S
S
C
S
H
K
L
S
Site 106
S1212
S
S
Q
S
R
K
S
S
C
S
H
K
L
S
S
Site 107
S1214
Q
S
R
K
S
S
C
S
H
K
L
S
S
C
N
Site 108
S1218
S
S
C
S
H
K
L
S
S
C
N
P
E
T
R
Site 109
S1219
S
C
S
H
K
L
S
S
C
N
P
E
T
R
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation