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Updated November 2019
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Protein Info
Short Name:
FAM47C
Full Name:
Putative protein FAM47C
Alias:
Type:
Mass (Da):
115338
Number AA:
1035
UniProt ID:
Q5HY64
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Q
R
P
Q
D
R
P
S
S
P
G
M
D
S
T
Site 2
S12
R
P
Q
D
R
P
S
S
P
G
M
D
S
T
P
Site 3
S17
P
S
S
P
G
M
D
S
T
P
W
Y
C
D
K
Site 4
T18
S
S
P
G
M
D
S
T
P
W
Y
C
D
K
P
Site 5
Y21
G
M
D
S
T
P
W
Y
C
D
K
P
P
S
K
Site 6
Y29
C
D
K
P
P
S
K
Y
F
A
K
R
K
H
R
Site 7
Y60
E
G
M
D
D
F
R
Y
G
C
Q
S
P
E
D
Site 8
S64
D
F
R
Y
G
C
Q
S
P
E
D
T
L
V
C
Site 9
T68
G
C
Q
S
P
E
D
T
L
V
C
R
R
D
E
Site 10
S82
E
F
L
L
P
K
I
S
L
R
G
P
Q
A
D
Site 11
S92
G
P
Q
A
D
P
K
S
R
K
K
K
L
L
K
Site 12
S108
A
A
L
F
S
K
L
S
P
A
Q
P
A
R
K
Site 13
Y134
T
K
H
P
L
A
M
Y
P
N
L
G
E
D
M
Site 14
S164
R
K
L
E
D
A
G
S
C
E
G
Q
E
K
T
Site 15
T176
E
K
T
T
D
E
P
T
E
P
G
K
Y
P
C
Site 16
Y181
E
P
T
E
P
G
K
Y
P
C
G
E
F
S
P
Site 17
S187
K
Y
P
C
G
E
F
S
P
R
P
P
E
T
R
Site 18
T193
F
S
P
R
P
P
E
T
R
V
S
C
L
P
P
Site 19
S196
R
P
P
E
T
R
V
S
C
L
P
P
E
P
P
Site 20
T205
L
P
P
E
P
P
K
T
P
V
S
S
L
R
P
Site 21
S208
E
P
P
K
T
P
V
S
S
L
R
P
E
P
P
Site 22
S209
P
P
K
T
P
V
S
S
L
R
P
E
P
P
E
Site 23
T217
L
R
P
E
P
P
E
T
G
V
S
H
L
R
P
Site 24
S220
E
P
P
E
T
G
V
S
H
L
R
P
Q
P
P
Site 25
T229
L
R
P
Q
P
P
K
T
Q
V
S
S
L
H
L
Site 26
T241
L
H
L
E
P
P
E
T
G
V
S
H
L
R
P
Site 27
S244
E
P
P
E
T
G
V
S
H
L
R
P
E
P
P
Site 28
T253
L
R
P
E
P
P
K
T
Q
V
S
S
L
H
L
Site 29
T265
L
H
L
E
P
P
E
T
G
V
S
H
L
Y
L
Site 30
S268
E
P
P
E
T
G
V
S
H
L
Y
L
E
P
P
Site 31
Y271
E
T
G
V
S
H
L
Y
L
E
P
P
G
T
G
Site 32
T289
L
C
P
E
P
P
K
T
R
V
S
H
L
H
R
Site 33
S292
E
P
P
K
T
R
V
S
H
L
H
R
E
P
P
Site 34
T301
L
H
R
E
P
P
E
T
G
V
P
D
L
C
L
Site 35
S313
L
C
L
E
P
P
K
S
R
V
S
H
L
R
P
Site 36
S316
E
P
P
K
S
R
V
S
H
L
R
P
E
P
S
Site 37
S323
S
H
L
R
P
E
P
S
E
T
G
V
S
H
L
Site 38
T325
L
R
P
E
P
S
E
T
G
V
S
H
L
H
P
Site 39
S328
E
P
S
E
T
G
V
S
H
L
H
P
E
P
P
Site 40
T337
L
H
P
E
P
P
K
T
L
V
S
S
L
H
P
Site 41
S341
P
P
K
T
L
V
S
S
L
H
P
E
P
P
E
Site 42
T349
L
H
P
E
P
P
E
T
G
V
S
H
L
C
P
Site 43
S352
E
P
P
E
T
G
V
S
H
L
C
P
E
P
P
Site 44
T361
L
C
P
E
P
P
E
T
R
V
S
P
L
R
Q
Site 45
S364
E
P
P
E
T
R
V
S
P
L
R
Q
L
P
P
Site 46
S376
L
P
P
E
A
G
V
S
H
L
C
P
E
P
P
Site 47
T385
L
C
P
E
P
P
K
T
R
V
P
P
L
R
P
Site 48
T394
V
P
P
L
R
P
E
T
P
K
N
G
V
S
P
Site 49
S400
E
T
P
K
N
G
V
S
P
L
F
P
E
P
P
Site 50
T409
L
F
P
E
P
P
K
T
R
I
S
N
L
R
S
Site 51
S412
E
P
P
K
T
R
I
S
N
L
R
S
E
P
P
Site 52
S416
T
R
I
S
N
L
R
S
E
P
P
K
I
G
V
Site 53
T433
L
C
L
E
P
P
K
T
R
G
S
H
L
R
P
Site 54
S436
E
P
P
K
T
R
G
S
H
L
R
P
E
P
P
Site 55
T457
L
R
P
E
P
P
K
T
R
V
S
S
L
H
L
Site 56
S460
E
P
P
K
T
R
V
S
S
L
H
L
E
P
P
Site 57
S461
P
P
K
T
R
V
S
S
L
H
L
E
P
P
E
Site 58
T469
L
H
L
E
P
P
E
T
G
V
S
H
L
C
P
Site 59
S484
E
P
P
E
K
D
V
S
H
L
R
P
E
P
P
Site 60
T493
L
R
P
E
P
P
D
T
G
V
S
H
L
C
P
Site 61
T505
L
C
P
E
P
P
K
T
R
V
S
H
L
R
P
Site 62
S508
E
P
P
K
T
R
V
S
H
L
R
P
E
P
S
Site 63
T517
L
R
P
E
P
S
E
T
G
V
S
H
L
R
P
Site 64
S520
E
P
S
E
T
G
V
S
H
L
R
P
E
P
P
Site 65
S541
L
H
Q
A
P
P
E
S
S
V
S
H
L
R
P
Site 66
S542
H
Q
A
P
P
E
S
S
V
S
H
L
R
P
E
Site 67
S544
A
P
P
E
S
S
V
S
H
L
R
P
E
P
P
Site 68
T565
L
R
P
E
P
P
K
T
R
M
Y
S
L
R
P
Site 69
Y568
E
P
P
K
T
R
M
Y
S
L
R
P
E
P
P
Site 70
S569
P
P
K
T
R
M
Y
S
L
R
P
E
P
P
D
Site 71
T589
L
C
P
E
P
P
K
T
R
V
S
S
L
P
P
Site 72
S592
E
P
P
K
T
R
V
S
S
L
P
P
E
P
P
Site 73
S593
P
P
K
T
R
V
S
S
L
P
P
E
P
P
E
Site 74
T601
L
P
P
E
P
P
E
T
G
V
S
H
L
C
P
Site 75
T613
L
C
P
E
P
P
E
T
R
V
S
H
L
R
P
Site 76
S616
E
P
P
E
T
R
V
S
H
L
R
P
E
P
P
Site 77
S641
P
P
K
T
R
M
Y
S
L
R
P
E
P
P
N
Site 78
T649
L
R
P
E
P
P
N
T
G
V
S
H
L
C
P
Site 79
T697
L
R
P
E
P
P
E
T
G
V
S
R
L
H
P
Site 80
S700
E
P
P
E
T
G
V
S
R
L
H
P
E
P
P
Site 81
T709
L
H
P
E
P
P
K
T
R
V
S
S
L
H
A
Site 82
S712
E
P
P
K
T
R
V
S
S
L
H
A
E
P
P
Site 83
S713
P
P
K
T
R
V
S
S
L
H
A
E
P
P
E
Site 84
S721
L
H
A
E
P
P
E
S
R
V
S
H
L
C
P
Site 85
S724
E
P
P
E
S
R
V
S
H
L
C
P
E
P
P
Site 86
T733
L
C
P
E
P
P
E
T
G
V
S
H
L
R
P
Site 87
S748
E
P
P
K
P
R
V
S
S
L
R
P
E
P
L
Site 88
S749
P
P
K
P
R
V
S
S
L
R
P
E
P
L
E
Site 89
T757
L
R
P
E
P
L
E
T
R
V
S
H
L
R
P
Site 90
S760
E
P
L
E
T
R
V
S
H
L
R
P
E
P
P
Site 91
T769
L
R
P
E
P
P
E
T
G
V
S
H
L
H
P
Site 92
S772
E
P
P
E
T
G
V
S
H
L
H
P
E
L
P
Site 93
S784
E
L
P
K
P
R
V
S
S
L
H
L
E
P
P
Site 94
S785
L
P
K
P
R
V
S
S
L
H
L
E
P
P
K
Site 95
T793
L
H
L
E
P
P
K
T
R
R
V
S
S
L
R
Site 96
S797
P
P
K
T
R
R
V
S
S
L
R
L
E
P
P
Site 97
S798
P
K
T
R
R
V
S
S
L
R
L
E
P
P
K
Site 98
T806
L
R
L
E
P
P
K
T
G
R
V
S
S
L
C
Site 99
S810
P
P
K
T
G
R
V
S
S
L
C
P
E
P
T
Site 100
S811
P
K
T
G
R
V
S
S
L
C
P
E
P
T
K
Site 101
T817
S
S
L
C
P
E
P
T
K
T
G
A
S
H
L
Site 102
T819
L
C
P
E
P
T
K
T
G
A
S
H
L
K
E
Site 103
S822
E
P
T
K
T
G
A
S
H
L
K
E
L
F
Q
Site 104
S834
L
F
Q
E
G
T
S
S
T
M
E
C
V
S
D
Site 105
S840
S
S
T
M
E
C
V
S
D
S
L
Q
R
R
H
Site 106
S842
T
M
E
C
V
S
D
S
L
Q
R
R
H
T
S
Site 107
T848
D
S
L
Q
R
R
H
T
S
R
K
L
R
D
F
Site 108
S849
S
L
Q
R
R
H
T
S
R
K
L
R
D
F
K
Site 109
S867
D
L
G
V
N
E
E
S
I
S
S
L
F
D
F
Site 110
S870
V
N
E
E
S
I
S
S
L
F
D
F
T
P
E
Site 111
T875
I
S
S
L
F
D
F
T
P
E
C
R
A
T
Y
Site 112
T881
F
T
P
E
C
R
A
T
Y
Q
D
Q
K
N
K
Site 113
Y882
T
P
E
C
R
A
T
Y
Q
D
Q
K
N
K
K
Site 114
S895
K
K
A
N
E
C
S
S
G
L
K
Y
S
M
E
Site 115
Y899
E
C
S
S
G
L
K
Y
S
M
E
L
D
E
M
Site 116
S913
M
D
E
V
K
F
F
S
Q
E
K
D
L
D
G
Site 117
S928
K
I
Q
N
A
P
N
S
H
S
A
Q
H
V
K
Site 118
Y942
K
M
G
Y
G
A
W
Y
L
K
P
K
L
G
K
Site 119
S953
K
L
G
K
K
L
R
S
D
E
P
L
I
D
P
Site 120
S988
A
F
K
D
F
I
L
S
K
G
Y
E
M
P
G
Site 121
T1007
L
F
A
R
R
G
W
T
Y
D
S
V
K
T
P
Site 122
Y1008
F
A
R
R
G
W
T
Y
D
S
V
K
T
P
I
Site 123
S1010
R
R
G
W
T
Y
D
S
V
K
T
P
I
Q
R
Site 124
T1013
W
T
Y
D
S
V
K
T
P
I
Q
R
A
M
Q
Site 125
Y1022
I
Q
R
A
M
Q
V
Y
K
Y
K
E
D
V
T
Site 126
Y1024
R
A
M
Q
V
Y
K
Y
K
E
D
V
T
D
A
Site 127
T1029
Y
K
Y
K
E
D
V
T
D
A
S
E
E
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation