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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX60L
Full Name:
Probable ATP-dependent RNA helicase DDX60-like
Alias:
DEAD box protein 60-like
Type:
Mass (Da):
152182
Number AA:
1308
UniProt ID:
Q5H9U9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y92
V
F
F
K
D
A
E
Y
A
Y
F
D
F
P
E
Site 2
Y94
F
K
D
A
E
Y
A
Y
F
D
F
P
E
L
L
Site 3
T121
N
T
N
I
D
V
Q
T
E
F
S
G
C
L
S
Site 4
Y141
L
L
E
Q
H
Y
P
Y
F
L
I
V
S
E
E
Site 5
S175
M
K
V
N
V
V
L
S
S
G
H
E
S
D
T
Site 6
S176
K
V
N
V
V
L
S
S
G
H
E
S
D
T
L
Site 7
S180
V
L
S
S
G
H
E
S
D
T
L
R
F
Y
A
Site 8
T182
S
S
G
H
E
S
D
T
L
R
F
Y
A
Y
T
Site 9
Y186
E
S
D
T
L
R
F
Y
A
Y
T
M
E
S
T
Site 10
Y188
D
T
L
R
F
Y
A
Y
T
M
E
S
T
D
R
Site 11
T189
T
L
R
F
Y
A
Y
T
M
E
S
T
D
R
N
Site 12
T193
Y
A
Y
T
M
E
S
T
D
R
N
Q
T
F
S
Site 13
T198
E
S
T
D
R
N
Q
T
F
S
K
E
N
E
T
Site 14
S200
T
D
R
N
Q
T
F
S
K
E
N
E
T
V
I
Site 15
S209
E
N
E
T
V
I
Q
S
A
Y
K
S
L
I
Q
Site 16
Y211
E
T
V
I
Q
S
A
Y
K
S
L
I
Q
H
L
Site 17
S213
V
I
Q
S
A
Y
K
S
L
I
Q
H
L
E
E
Site 18
Y243
N
D
M
M
E
E
A
Y
Q
T
L
F
L
L
Q
Site 19
S282
Y
H
R
V
L
V
H
S
N
C
L
S
L
Q
E
Site 20
S310
F
Q
L
H
L
P
L
S
Q
R
A
C
S
R
V
Site 21
S315
P
L
S
Q
R
A
C
S
R
V
I
T
C
S
W
Site 22
T319
R
A
C
S
R
V
I
T
C
S
W
I
R
N
S
Site 23
Y361
L
N
H
V
S
D
L
Y
D
E
Q
L
L
K
N
Site 24
Y372
L
L
K
N
I
A
F
Y
Y
E
F
E
S
T
Q
Site 25
Y373
L
K
N
I
A
F
Y
Y
E
F
E
S
T
Q
E
Site 26
T378
F
Y
Y
E
F
E
S
T
Q
E
P
H
L
N
L
Site 27
S388
P
H
L
N
L
G
D
S
I
R
R
D
Y
E
D
Site 28
Y393
G
D
S
I
R
R
D
Y
E
D
L
W
N
V
V
Site 29
S412
K
E
F
N
V
G
K
S
F
P
L
R
T
T
R
Site 30
T417
G
K
S
F
P
L
R
T
T
R
R
H
F
L
R
Site 31
T418
K
S
F
P
L
R
T
T
R
R
H
F
L
R
Q
Site 32
S428
H
F
L
R
Q
E
K
S
V
I
Q
E
I
S
L
Site 33
S434
K
S
V
I
Q
E
I
S
L
E
K
M
P
S
V
Site 34
S467
K
D
L
P
I
L
K
S
D
D
P
V
V
P
S
Site 35
S474
S
D
D
P
V
V
P
S
L
F
K
Q
K
T
S
Site 36
T480
P
S
L
F
K
Q
K
T
S
D
E
L
L
H
W
Site 37
S481
S
L
F
K
Q
K
T
S
D
E
L
L
H
W
H
Site 38
S494
W
H
A
Q
R
L
L
S
D
D
Y
D
R
I
K
Site 39
Y497
Q
R
L
L
S
D
D
Y
D
R
I
K
C
H
V
Site 40
S508
K
C
H
V
D
E
Q
S
R
D
P
H
V
L
D
Site 41
Y523
F
L
K
K
I
Q
D
Y
Q
Q
F
Y
G
K
S
Site 42
S530
Y
Q
Q
F
Y
G
K
S
L
E
S
I
S
T
K
Site 43
T536
K
S
L
E
S
I
S
T
K
V
I
V
T
Q
T
Site 44
T543
T
K
V
I
V
T
Q
T
T
R
P
K
E
D
S
Site 45
S550
T
T
R
P
K
E
D
S
S
G
A
S
G
E
I
Site 46
S551
T
R
P
K
E
D
S
S
G
A
S
G
E
I
L
Site 47
S554
K
E
D
S
S
G
A
S
G
E
I
L
Q
N
T
Site 48
S570
P
H
Q
I
T
K
K
S
K
K
K
S
F
L
K
Site 49
S574
T
K
K
S
K
K
K
S
F
L
K
E
D
Q
N
Site 50
S592
Q
N
D
D
L
L
F
S
I
E
E
E
M
K
N
Site 51
S603
E
M
K
N
N
L
H
S
G
I
R
K
L
E
D
Site 52
Y611
G
I
R
K
L
E
D
Y
L
T
S
C
A
S
N
Site 53
T613
R
K
L
E
D
Y
L
T
S
C
A
S
N
S
V
Site 54
S614
K
L
E
D
Y
L
T
S
C
A
S
N
S
V
K
Site 55
S647
C
R
G
E
G
K
I
S
K
D
L
S
I
A
V
Site 56
S651
G
K
I
S
K
D
L
S
I
A
V
Q
M
M
K
Site 57
S662
Q
M
M
K
R
I
H
S
L
L
E
R
Y
P
E
Site 58
Y667
I
H
S
L
L
E
R
Y
P
E
I
L
E
A
E
Site 59
Y678
L
E
A
E
H
H
Q
Y
I
A
K
C
L
K
Y
Site 60
T698
L
A
N
S
L
D
P
T
L
I
G
D
D
K
N
Site 61
Y709
D
D
K
N
K
K
K
Y
S
I
D
I
G
P
A
Site 62
S710
D
K
N
K
K
K
Y
S
I
D
I
G
P
A
R
Site 63
Y722
P
A
R
F
Q
L
Q
Y
M
G
H
Y
L
I
R
Site 64
Y726
Q
L
Q
Y
M
G
H
Y
L
I
R
D
E
R
K
Site 65
T772
A
P
T
S
S
G
K
T
Y
A
S
Y
Y
C
M
Site 66
Y773
P
T
S
S
G
K
T
Y
A
S
Y
Y
C
M
E
Site 67
Y776
S
G
K
T
Y
A
S
Y
Y
C
M
E
K
V
L
Site 68
Y777
G
K
T
Y
A
S
Y
Y
C
M
E
K
V
L
R
Site 69
T813
A
T
V
E
N
R
F
T
K
T
L
P
A
G
R
Site 70
T815
V
E
N
R
F
T
K
T
L
P
A
G
R
T
P
Site 71
T821
K
T
L
P
A
G
R
T
P
C
G
A
F
T
R
Site 72
Y830
C
G
A
F
T
R
D
Y
R
H
N
V
L
N
C
Site 73
Y865
K
W
V
E
R
I
R
Y
V
I
F
D
E
V
H
Site 74
Y947
N
F
L
Q
D
H
S
Y
K
N
Q
S
Y
E
V
Site 75
Y952
H
S
Y
K
N
Q
S
Y
E
V
R
L
V
L
C
Site 76
Y963
L
V
L
C
G
E
R
Y
N
D
L
E
K
H
I
Site 77
Y979
S
V
K
H
D
D
V
Y
F
D
H
F
H
P
C
Site 78
Y997
T
T
D
I
I
E
K
Y
G
F
P
P
D
L
T
Site 79
T1004
Y
G
F
P
P
D
L
T
L
T
P
Q
E
S
I
Site 80
T1006
F
P
P
D
L
T
L
T
P
Q
E
S
I
Q
L
Site 81
Y1014
P
Q
E
S
I
Q
L
Y
D
T
M
A
Q
V
W
Site 82
T1016
E
S
I
Q
L
Y
D
T
M
A
Q
V
W
E
T
Site 83
Y1052
K
K
L
D
A
R
K
Y
E
E
N
L
K
A
E
Site 84
S1080
K
R
V
L
K
N
L
S
P
D
S
L
S
S
S
Site 85
S1083
L
K
N
L
S
P
D
S
L
S
S
S
K
D
M
Site 86
S1085
N
L
S
P
D
S
L
S
S
S
K
D
M
V
K
Site 87
S1087
S
P
D
S
L
S
S
S
K
D
M
V
K
M
F
Site 88
S1125
D
V
G
K
R
A
G
S
V
C
T
F
L
E
K
Site 89
T1133
V
C
T
F
L
E
K
T
E
T
K
S
H
P
H
Site 90
T1135
T
F
L
E
K
T
E
T
K
S
H
P
H
T
E
Site 91
S1137
L
E
K
T
E
T
K
S
H
P
H
T
E
C
H
Site 92
T1141
E
T
K
S
H
P
H
T
E
C
H
S
Y
V
F
Site 93
Y1146
P
H
T
E
C
H
S
Y
V
F
A
I
D
E
V
Site 94
T1160
V
L
E
K
V
R
K
T
Q
K
R
I
S
T
K
Site 95
S1165
R
K
T
Q
K
R
I
S
T
K
K
N
P
K
K
Site 96
T1166
K
T
Q
K
R
I
S
T
K
K
N
P
K
K
A
Site 97
Y1186
K
K
V
Y
R
A
E
Y
I
N
F
L
E
N
L
Site 98
Y1204
E
I
S
E
D
C
T
Y
A
D
V
K
A
L
H
Site 99
T1221
I
T
R
N
K
D
S
T
L
D
R
V
L
P
R
Site 100
T1232
V
L
P
R
V
R
F
T
R
H
G
K
E
L
K
Site 101
Y1248
L
A
Q
R
G
I
G
Y
H
H
S
S
M
Y
F
Site 102
Y1254
G
Y
H
H
S
S
M
Y
F
K
E
K
E
F
V
Site 103
Y1298
V
F
A
Q
D
S
V
Y
L
D
A
L
N
Y
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation