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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARSH
Full Name:
Arylsulfatase H
Alias:
Type:
Mass (Da):
63525
Number AA:
562
UniProt ID:
Q5FYA8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
G
V
G
D
L
C
C
Y
G
N
N
S
V
S
T
Site 2
S31
C
Y
G
N
N
S
V
S
T
P
N
I
D
R
L
Site 3
T32
Y
G
N
N
S
V
S
T
P
N
I
D
R
L
A
Site 4
S40
P
N
I
D
R
L
A
S
E
G
V
R
L
T
Q
Site 5
T46
A
S
E
G
V
R
L
T
Q
H
L
A
A
A
S
Site 6
S53
T
Q
H
L
A
A
A
S
M
C
T
P
S
R
A
Site 7
T64
P
S
R
A
A
F
L
T
G
R
Y
P
I
R
S
Site 8
S71
T
G
R
Y
P
I
R
S
G
M
V
S
A
Y
N
Site 9
S75
P
I
R
S
G
M
V
S
A
Y
N
L
N
R
A
Site 10
T84
Y
N
L
N
R
A
F
T
W
L
G
G
S
G
G
Site 11
T97
G
G
L
P
T
N
E
T
T
F
A
K
L
L
Q
Site 12
T98
G
L
P
T
N
E
T
T
F
A
K
L
L
Q
H
Site 13
Y108
K
L
L
Q
H
R
G
Y
R
T
G
L
I
G
K
Site 14
Y130
A
S
R
N
D
H
C
Y
H
P
L
N
H
G
F
Site 15
Y139
P
L
N
H
G
F
H
Y
F
Y
G
V
P
F
G
Site 16
S154
L
L
S
D
C
Q
A
S
K
T
P
E
L
H
R
Site 17
T156
S
D
C
Q
A
S
K
T
P
E
L
H
R
W
L
Site 18
Y212
F
L
F
F
T
S
W
Y
S
S
Y
G
F
T
R
Site 19
S243
M
K
E
E
K
V
A
S
L
M
L
K
E
A
L
Site 20
T272
F
S
F
L
H
V
H
T
P
L
I
S
K
K
K
Site 21
Y286
K
F
V
G
R
S
K
Y
G
R
Y
G
D
N
V
Site 22
T316
Q
E
R
L
A
N
H
T
L
V
Y
F
T
S
D
Site 23
Y319
L
A
N
H
T
L
V
Y
F
T
S
D
N
G
G
Site 24
Y344
L
G
G
W
N
G
I
Y
K
G
G
K
G
M
G
Site 25
S380
R
V
I
N
E
P
T
S
L
M
D
I
Y
P
T
Site 26
S416
P
L
L
E
G
R
A
S
H
S
D
H
E
F
L
Site 27
S418
L
E
G
R
A
S
H
S
D
H
E
F
L
F
H
Site 28
Y449
A
T
V
W
K
A
H
Y
V
T
P
K
F
Y
P
Site 29
T451
V
W
K
A
H
Y
V
T
P
K
F
Y
P
E
G
Site 30
Y455
H
Y
V
T
P
K
F
Y
P
E
G
T
G
A
C
Site 31
S471
G
S
G
I
C
S
C
S
G
D
V
T
Y
H
D
Site 32
T475
C
S
C
S
G
D
V
T
Y
H
D
P
P
L
L
Site 33
Y476
S
C
S
G
D
V
T
Y
H
D
P
P
L
L
F
Site 34
S486
P
P
L
L
F
D
I
S
R
D
P
S
E
A
L
Site 35
S490
F
D
I
S
R
D
P
S
E
A
L
P
L
N
P
Site 36
S505
D
N
E
P
L
F
D
S
V
I
K
K
M
E
A
Site 37
T520
A
I
R
E
H
R
R
T
L
T
P
V
P
Q
Q
Site 38
T522
R
E
H
R
R
T
L
T
P
V
P
Q
Q
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation