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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSP90AA5P
Full Name:
Putative heat shock protein HSP 90-alpha A5
Alias:
HSP90AE
Type:
Chaperone protein
Mass (Da):
38738
Number AA:
334
UniProt ID:
Q58FG0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
G
L
E
L
L
T
S
G
H
P
A
L
E
R
Site 2
Y27
A
L
E
R
R
P
E
Y
L
E
E
R
R
I
K
Site 3
S41
K
E
I
V
K
K
H
S
Q
F
I
G
Y
P
I
Site 4
T49
Q
F
I
G
Y
P
I
T
L
F
V
E
K
K
R
Site 5
S61
K
K
R
N
K
Q
V
S
D
A
E
A
E
K
K
Site 6
S89
P
E
I
E
D
V
G
S
D
E
E
E
E
K
K
Site 7
S105
A
D
K
K
K
K
K
S
K
E
K
Y
I
D
Q
Site 8
Y109
K
K
K
S
K
E
K
Y
I
D
Q
E
L
N
K
Site 9
T117
I
D
Q
E
L
N
K
T
K
P
I
W
T
R
N
Site 10
T129
T
R
N
P
D
A
I
T
N
E
E
Y
G
E
F
Site 11
S165
Q
L
E
E
L
K
D
S
R
R
V
M
K
A
N
Site 12
Y177
K
A
N
Q
K
H
I
Y
Y
I
T
G
E
T
K
Site 13
Y178
A
N
Q
K
H
I
Y
Y
I
T
G
E
T
K
D
Site 14
S190
T
K
D
Q
V
A
N
S
A
F
V
E
C
L
Q
Site 15
Y205
K
H
G
L
E
V
I
Y
M
I
E
L
I
D
K
Site 16
Y213
M
I
E
L
I
D
K
Y
C
V
Q
Q
L
K
E
Site 17
S223
Q
Q
L
K
E
L
E
S
K
T
V
V
S
V
A
Site 18
T225
L
K
E
L
E
S
K
T
V
V
S
V
A
K
E
Site 19
T251
K
K
Q
E
E
K
K
T
K
F
E
N
L
C
K
Site 20
Y288
Q
R
H
T
N
K
I
Y
R
M
I
K
L
G
L
Site 21
Y300
L
G
L
G
V
D
E
Y
D
P
T
A
N
D
I
Site 22
T303
G
V
D
E
Y
D
P
T
A
N
D
I
N
A
A
Site 23
T324
P
L
R
G
G
D
D
T
S
R
M
E
E
V
G
Site 24
S325
L
R
G
G
D
D
T
S
R
M
E
E
V
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation