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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BRDT
Full Name:
Bromodomain testis-specific protein
Alias:
BRD6; Bromodomain, testis-specific; Cancer,testis antigen 9; Cancer/testis antigen 9; CT9; RING3-like protein
Type:
Protein kinase, Ser/Thr (non-receptor);
ATYPICAL
group; BRD family
Mass (Da):
107954
Number AA:
947
UniProt ID:
Q58F21
International Prot ID:
IPI00645771
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004674
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
S
L
P
S
R
Q
T
A
I
I
V
N
P
P
Site 2
Y19
V
N
P
P
P
P
E
Y
I
N
T
K
K
N
G
Site 3
T22
P
P
P
E
Y
I
N
T
K
K
N
G
R
L
T
Site 4
T29
T
K
K
N
G
R
L
T
N
Q
L
Q
Y
L
Q
Site 5
Y66
V
K
L
Q
L
P
D
Y
Y
T
I
I
K
N
P
Site 6
Y67
K
L
Q
L
P
D
Y
Y
T
I
I
K
N
P
M
Site 7
T68
L
Q
L
P
D
Y
Y
T
I
I
K
N
P
M
D
Site 8
T78
K
N
P
M
D
L
N
T
I
K
K
R
L
E
N
Site 9
Y87
K
K
R
L
E
N
K
Y
Y
A
K
A
S
E
C
Site 10
Y88
K
R
L
E
N
K
Y
Y
A
K
A
S
E
C
I
Site 11
Y106
N
T
M
F
S
N
C
Y
L
Y
N
K
P
G
D
Site 12
Y108
M
F
S
N
C
Y
L
Y
N
K
P
G
D
D
I
Site 13
S131
K
L
F
M
Q
K
L
S
Q
M
P
Q
E
E
Q
Site 14
T150
K
E
R
I
K
K
G
T
Q
Q
N
I
A
V
S
Site 15
S163
V
S
S
A
K
E
K
S
S
P
S
A
T
E
K
Site 16
S164
S
S
A
K
E
K
S
S
P
S
A
T
E
K
V
Site 17
T168
E
K
S
S
P
S
A
T
E
K
V
F
K
Q
Q
Site 18
S179
F
K
Q
Q
E
I
P
S
V
F
P
K
T
S
I
Site 19
S196
L
N
V
V
Q
G
A
S
V
N
S
S
S
Q
T
Site 20
S199
V
Q
G
A
S
V
N
S
S
S
Q
T
A
A
Q
Site 21
S200
Q
G
A
S
V
N
S
S
S
Q
T
A
A
Q
V
Site 22
S201
G
A
S
V
N
S
S
S
Q
T
A
A
Q
V
T
Site 23
T203
S
V
N
S
S
S
Q
T
A
A
Q
V
T
K
G
Site 24
T217
G
V
K
R
K
A
D
T
T
T
P
A
T
S
A
Site 25
T218
V
K
R
K
A
D
T
T
T
P
A
T
S
A
V
Site 26
T219
K
R
K
A
D
T
T
T
P
A
T
S
A
V
K
Site 27
S223
D
T
T
T
P
A
T
S
A
V
K
A
S
S
E
Site 28
S228
A
T
S
A
V
K
A
S
S
E
F
S
P
T
F
Site 29
S229
T
S
A
V
K
A
S
S
E
F
S
P
T
F
T
Site 30
S232
V
K
A
S
S
E
F
S
P
T
F
T
E
K
S
Site 31
T234
A
S
S
E
F
S
P
T
F
T
E
K
S
V
A
Site 32
T236
S
E
F
S
P
T
F
T
E
K
S
V
A
L
P
Site 33
S239
S
P
T
F
T
E
K
S
V
A
L
P
P
I
K
Site 34
S257
P
K
N
V
L
P
D
S
Q
Q
Q
Y
N
V
V
Site 35
Y261
L
P
D
S
Q
Q
Q
Y
N
V
V
K
T
V
K
Site 36
T266
Q
Q
Y
N
V
V
K
T
V
K
V
T
E
Q
L
Site 37
S277
T
E
Q
L
R
H
C
S
E
I
L
K
E
M
L
Site 38
Y291
L
A
K
K
H
F
S
Y
A
W
P
F
Y
N
P
Site 39
Y296
F
S
Y
A
W
P
F
Y
N
P
V
D
V
N
A
Site 40
Y309
N
A
L
G
L
H
N
Y
Y
D
V
V
K
N
P
Site 41
Y310
A
L
G
L
H
N
Y
Y
D
V
V
K
N
P
M
Site 42
Y335
N
Q
E
Y
K
D
A
Y
K
F
A
A
D
V
R
Site 43
T360
P
P
D
H
E
V
V
T
M
A
R
M
L
Q
D
Site 44
S374
D
V
F
E
T
H
F
S
K
I
P
I
E
P
V
Site 45
T391
M
P
L
C
Y
I
K
T
D
I
T
E
T
T
G
Site 46
T394
C
Y
I
K
T
D
I
T
E
T
T
G
R
E
N
Site 47
T402
E
T
T
G
R
E
N
T
N
E
A
S
S
E
G
Site 48
S406
R
E
N
T
N
E
A
S
S
E
G
N
S
S
D
Site 49
S407
E
N
T
N
E
A
S
S
E
G
N
S
S
D
D
Site 50
S411
E
A
S
S
E
G
N
S
S
D
D
S
E
D
E
Site 51
S412
A
S
S
E
G
N
S
S
D
D
S
E
D
E
R
Site 52
S415
E
G
N
S
S
D
D
S
E
D
E
R
V
K
R
Site 53
S441
H
Q
Q
L
Q
V
L
S
Q
V
P
F
R
K
L
Site 54
S455
L
N
K
K
K
E
K
S
K
K
E
K
K
K
E
Site 55
S484
Q
M
R
L
K
E
K
S
K
R
N
Q
P
K
K
Site 56
S501
Q
Q
F
I
G
L
K
S
E
D
E
D
N
A
K
Site 57
S519
Y
D
E
K
R
Q
L
S
L
N
I
N
K
L
P
Site 58
S539
R
V
V
H
I
I
Q
S
R
E
P
S
L
S
N
Site 59
S543
I
I
Q
S
R
E
P
S
L
S
N
S
N
P
D
Site 60
S545
Q
S
R
E
P
S
L
S
N
S
N
P
D
E
I
Site 61
S547
R
E
P
S
L
S
N
S
N
P
D
E
I
E
I
Site 62
T558
E
I
E
I
D
F
E
T
L
K
A
S
T
L
R
Site 63
S562
D
F
E
T
L
K
A
S
T
L
R
E
L
E
K
Site 64
Y570
T
L
R
E
L
E
K
Y
V
S
A
C
L
R
K
Site 65
S572
R
E
L
E
K
Y
V
S
A
C
L
R
K
R
P
Site 66
S590
P
A
K
K
I
M
M
S
K
E
E
L
H
S
Q
Site 67
S596
M
S
K
E
E
L
H
S
Q
K
K
Q
E
L
E
Site 68
T620
L
N
S
R
K
R
Q
T
K
S
D
K
T
Q
P
Site 69
S622
S
R
K
R
Q
T
K
S
D
K
T
Q
P
S
K
Site 70
T625
R
Q
T
K
S
D
K
T
Q
P
S
K
A
V
E
Site 71
S635
S
K
A
V
E
N
V
S
R
L
S
E
S
S
S
Site 72
S638
V
E
N
V
S
R
L
S
E
S
S
S
S
S
S
Site 73
S640
N
V
S
R
L
S
E
S
S
S
S
S
S
S
S
Site 74
S641
V
S
R
L
S
E
S
S
S
S
S
S
S
S
S
Site 75
S642
S
R
L
S
E
S
S
S
S
S
S
S
S
S
E
Site 76
S643
R
L
S
E
S
S
S
S
S
S
S
S
S
E
S
Site 77
S644
L
S
E
S
S
S
S
S
S
S
S
S
E
S
E
Site 78
S645
S
E
S
S
S
S
S
S
S
S
S
E
S
E
S
Site 79
S646
E
S
S
S
S
S
S
S
S
S
E
S
E
S
S
Site 80
S647
S
S
S
S
S
S
S
S
S
E
S
E
S
S
S
Site 81
S648
S
S
S
S
S
S
S
S
E
S
E
S
S
S
S
Site 82
S650
S
S
S
S
S
S
E
S
E
S
S
S
S
D
L
Site 83
S652
S
S
S
S
E
S
E
S
S
S
S
D
L
S
S
Site 84
S653
S
S
S
E
S
E
S
S
S
S
D
L
S
S
S
Site 85
S654
S
S
E
S
E
S
S
S
S
D
L
S
S
S
D
Site 86
S655
S
E
S
E
S
S
S
S
D
L
S
S
S
D
S
Site 87
S658
E
S
S
S
S
D
L
S
S
S
D
S
S
D
S
Site 88
S659
S
S
S
S
D
L
S
S
S
D
S
S
D
S
E
Site 89
S660
S
S
S
D
L
S
S
S
D
S
S
D
S
E
S
Site 90
S662
S
D
L
S
S
S
D
S
S
D
S
E
S
E
M
Site 91
S663
D
L
S
S
S
D
S
S
D
S
E
S
E
M
F
Site 92
S665
S
S
S
D
S
S
D
S
E
S
E
M
F
P
K
Site 93
S667
S
D
S
S
D
S
E
S
E
M
F
P
K
F
T
Site 94
S681
T
E
V
K
P
N
D
S
P
S
K
E
N
V
K
Site 95
S683
V
K
P
N
D
S
P
S
K
E
N
V
K
K
M
Site 96
Y708
T
G
V
T
Q
I
G
Y
C
V
Q
D
T
T
S
Site 97
T713
I
G
Y
C
V
Q
D
T
T
S
A
N
T
T
L
Site 98
T719
D
T
T
S
A
N
T
T
L
V
H
Q
T
T
P
Site 99
T725
T
T
L
V
H
Q
T
T
P
S
H
V
M
P
P
Site 100
T749
Q
E
L
E
H
L
Q
T
V
K
N
I
S
P
L
Site 101
S762
P
L
Q
I
L
P
P
S
G
D
S
E
Q
L
S
Site 102
S765
I
L
P
P
S
G
D
S
E
Q
L
S
N
G
I
Site 103
S769
S
G
D
S
E
Q
L
S
N
G
I
T
V
M
H
Site 104
T773
E
Q
L
S
N
G
I
T
V
M
H
P
S
G
D
Site 105
S781
V
M
H
P
S
G
D
S
D
T
T
M
L
E
S
Site 106
T783
H
P
S
G
D
S
D
T
T
M
L
E
S
E
C
Site 107
T784
P
S
G
D
S
D
T
T
M
L
E
S
E
C
Q
Site 108
S788
S
D
T
T
M
L
E
S
E
C
Q
A
P
V
Q
Site 109
S805
I
K
I
K
N
A
D
S
W
K
S
L
G
K
P
Site 110
S808
K
N
A
D
S
W
K
S
L
G
K
P
V
K
P
Site 111
S816
L
G
K
P
V
K
P
S
G
V
M
K
S
S
D
Site 112
S821
K
P
S
G
V
M
K
S
S
D
E
L
F
N
Q
Site 113
S822
P
S
G
V
M
K
S
S
D
E
L
F
N
Q
F
Site 114
S860
N
T
K
E
L
K
A
S
Q
E
N
Q
R
D
L
Site 115
T872
R
D
L
G
N
G
L
T
V
E
S
F
S
N
K
Site 116
S875
G
N
G
L
T
V
E
S
F
S
N
K
I
Q
N
Site 117
S895
E
Q
K
E
H
Q
Q
S
S
E
A
Q
D
K
S
Site 118
S896
Q
K
E
H
Q
Q
S
S
E
A
Q
D
K
S
K
Site 119
S902
S
S
E
A
Q
D
K
S
K
L
W
L
L
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation