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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLE1
Full Name:
Nucleoporin GLE1
Alias:
GLE1 RNA export mediator; GLE1L; GLE1-like protein; HGLE1; LCCS1
Type:
Karyopherin
Mass (Da):
79836
Number AA:
698
UniProt ID:
Q53GS7
International Prot ID:
IPI00301647
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005643
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006405
GO:0006406
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
S
E
G
R
C
W
E
T
L
K
A
L
R
S
S
Site 2
S16
E
T
L
K
A
L
R
S
S
D
K
G
R
L
C
Site 3
S17
T
L
K
A
L
R
S
S
D
K
G
R
L
C
Y
Site 4
Y24
S
D
K
G
R
L
C
Y
Y
R
D
W
L
L
R
Site 5
Y25
D
K
G
R
L
C
Y
Y
R
D
W
L
L
R
R
Site 6
S41
D
V
L
E
E
C
M
S
L
P
K
L
S
S
Y
Site 7
S47
M
S
L
P
K
L
S
S
Y
S
G
W
V
V
E
Site 8
S67
M
Q
E
N
Q
P
L
S
E
T
S
P
S
S
T
Site 9
T69
E
N
Q
P
L
S
E
T
S
P
S
S
T
S
A
Site 10
S70
N
Q
P
L
S
E
T
S
P
S
S
T
S
A
S
Site 11
S72
P
L
S
E
T
S
P
S
S
T
S
A
S
A
L
Site 12
S73
L
S
E
T
S
P
S
S
T
S
A
S
A
L
D
Site 13
T74
S
E
T
S
P
S
S
T
S
A
S
A
L
D
Q
Site 14
S77
S
P
S
S
T
S
A
S
A
L
D
Q
P
S
F
Site 15
S83
A
S
A
L
D
Q
P
S
F
V
P
K
S
P
D
Site 16
S88
Q
P
S
F
V
P
K
S
P
D
A
S
S
A
F
Site 17
S92
V
P
K
S
P
D
A
S
S
A
F
S
P
A
S
Site 18
S93
P
K
S
P
D
A
S
S
A
F
S
P
A
S
P
Site 19
S96
P
D
A
S
S
A
F
S
P
A
S
P
A
T
P
Site 20
S99
S
S
A
F
S
P
A
S
P
A
T
P
N
G
T
Site 21
T102
F
S
P
A
S
P
A
T
P
N
G
T
K
G
K
Site 22
T106
S
P
A
T
P
N
G
T
K
G
K
D
E
S
Q
Site 23
S112
G
T
K
G
K
D
E
S
Q
H
T
E
S
M
V
Site 24
T115
G
K
D
E
S
Q
H
T
E
S
M
V
L
Q
S
Site 25
S117
D
E
S
Q
H
T
E
S
M
V
L
Q
S
S
R
Site 26
S122
T
E
S
M
V
L
Q
S
S
R
G
I
K
V
E
Site 27
S123
E
S
M
V
L
Q
S
S
R
G
I
K
V
E
G
Site 28
Y135
V
E
G
C
V
R
M
Y
E
L
V
H
R
M
K
Site 29
S162
E
R
K
V
Q
A
L
S
E
M
A
S
E
Q
L
Site 30
S166
Q
A
L
S
E
M
A
S
E
Q
L
K
R
F
D
Site 31
S194
L
R
E
V
M
E
K
S
S
R
E
A
L
G
H
Site 32
S259
Q
E
E
M
L
Q
L
S
Q
Q
L
D
A
S
E
Site 33
S297
I
S
G
I
I
R
A
S
S
E
S
S
Y
P
T
Site 34
S298
S
G
I
I
R
A
S
S
E
S
S
Y
P
T
A
Site 35
S300
I
I
R
A
S
S
E
S
S
Y
P
T
A
E
S
Site 36
S301
I
R
A
S
S
E
S
S
Y
P
T
A
E
S
Q
Site 37
Y302
R
A
S
S
E
S
S
Y
P
T
A
E
S
Q
A
Site 38
T304
S
S
E
S
S
Y
P
T
A
E
S
Q
A
E
A
Site 39
S307
S
S
Y
P
T
A
E
S
Q
A
E
A
E
R
A
Site 40
S367
H
K
E
P
P
A
P
S
Q
G
P
G
G
K
Q
Site 41
S410
T
F
E
G
L
T
N
S
K
D
S
Q
A
K
K
Site 42
S413
G
L
T
N
S
K
D
S
Q
A
K
K
I
K
M
Site 43
S453
D
K
I
H
S
L
L
S
G
K
P
V
Q
S
G
Site 44
S459
L
S
G
K
P
V
Q
S
G
G
R
S
V
S
V
Site 45
S463
P
V
Q
S
G
G
R
S
V
S
V
T
L
N
P
Site 46
S465
Q
S
G
G
R
S
V
S
V
T
L
N
P
Q
G
Site 47
T467
G
G
R
S
V
S
V
T
L
N
P
Q
G
L
D
Site 48
Y478
Q
G
L
D
F
V
Q
Y
K
L
A
E
K
F
V
Site 49
S494
Q
G
E
E
E
V
A
S
H
H
E
A
A
F
P
Site 50
Y530
H
L
H
K
K
C
P
Y
S
V
P
F
Y
P
T
Site 51
Y535
C
P
Y
S
V
P
F
Y
P
T
F
K
E
G
M
Site 52
Y547
E
G
M
A
L
E
D
Y
Q
R
M
L
G
Y
Q
Site 53
Y553
D
Y
Q
R
M
L
G
Y
Q
V
K
D
S
K
V
Site 54
S558
L
G
Y
Q
V
K
D
S
K
V
E
Q
Q
D
N
Site 55
Y587
I
I
Q
L
R
W
P
Y
G
N
R
Q
E
I
H
Site 56
Y652
L
I
L
I
K
E
D
Y
F
P
R
I
E
A
I
Site 57
T660
F
P
R
I
E
A
I
T
S
S
G
Q
M
G
S
Site 58
S661
P
R
I
E
A
I
T
S
S
G
Q
M
G
S
F
Site 59
S667
T
S
S
G
Q
M
G
S
F
I
R
L
K
Q
F
Site 60
T692
P
V
P
K
G
F
L
T
S
S
F
W
R
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation