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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARP10
Full Name:
Poly [ADP-ribose] polymerase 10
Alias:
PARP-10
Type:
Mass (Da):
109980
Number AA:
1025
UniProt ID:
Q53GL7
International Prot ID:
IPI00064457
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0003950
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
A
V
P
D
E
L
L
T
L
Y
F
E
N
R
R
Site 2
Y30
P
D
E
L
L
T
L
Y
F
E
N
R
R
R
S
Site 3
S37
Y
F
E
N
R
R
R
S
G
G
G
P
V
L
S
Site 4
S44
S
G
G
G
P
V
L
S
W
Q
R
L
G
C
G
Site 5
S79
E
L
H
G
A
Q
L
S
L
R
P
A
P
P
R
Site 6
T101
Q
G
L
P
P
G
T
T
P
Q
R
L
E
Q
H
Site 7
S128
Q
P
C
C
A
L
A
S
P
R
P
D
R
A
L
Site 8
Y192
D
L
L
L
L
E
L
Y
L
E
N
E
R
R
S
Site 9
S199
Y
L
E
N
E
R
R
S
G
G
G
P
L
E
D
Site 10
T216
R
L
P
G
P
L
G
T
V
A
S
F
Q
Q
W
Site 11
S239
Q
E
H
R
L
Q
G
S
E
L
S
L
V
P
H
Site 12
S242
R
L
Q
G
S
E
L
S
L
V
P
H
Y
D
I
Site 13
Y247
E
L
S
L
V
P
H
Y
D
I
L
E
P
E
E
Site 14
S260
E
E
L
A
E
N
T
S
G
G
D
H
P
S
T
Site 15
S266
T
S
G
G
D
H
P
S
T
Q
G
P
R
A
T
Site 16
T267
S
G
G
D
H
P
S
T
Q
G
P
R
A
T
K
Site 17
T273
S
T
Q
G
P
R
A
T
K
H
A
L
L
R
T
Site 18
S297
A
G
T
V
T
M
G
S
G
E
E
P
G
Q
S
Site 19
S304
S
G
E
E
P
G
Q
S
G
A
S
L
R
T
G
Site 20
S307
E
P
G
Q
S
G
A
S
L
R
T
G
P
M
V
Site 21
T322
Q
G
R
G
I
M
T
T
G
S
G
Q
E
P
G
Site 22
S324
R
G
I
M
T
T
G
S
G
Q
E
P
G
Q
S
Site 23
S331
S
G
Q
E
P
G
Q
S
G
T
S
L
R
T
G
Site 24
S334
E
P
G
Q
S
G
T
S
L
R
T
G
P
M
G
Site 25
S342
L
R
T
G
P
M
G
S
L
G
Q
A
E
Q
V
Site 26
S350
L
G
Q
A
E
Q
V
S
S
M
P
M
G
S
L
Site 27
S351
G
Q
A
E
Q
V
S
S
M
P
M
G
S
L
E
Site 28
S378
Q
E
Q
E
G
P
M
S
L
G
P
V
G
S
A
Site 29
S431
L
E
K
A
G
P
V
S
P
G
C
V
K
L
A
Site 30
T483
P
L
E
G
P
D
M
T
G
F
R
L
C
G
A
Site 31
T553
T
E
R
L
A
T
A
T
L
D
T
G
L
E
E
Site 32
T579
G
N
A
H
T
L
W
T
P
D
S
T
G
G
D
Site 33
S582
H
T
L
W
T
P
D
S
T
G
G
D
Q
E
D
Site 34
S591
G
G
D
Q
E
D
V
S
L
E
E
V
R
E
L
Site 35
T631
E
Q
P
E
E
E
V
T
P
G
H
E
E
E
E
Site 36
T644
E
E
P
V
A
P
S
T
V
A
P
R
W
L
E
Site 37
S663
L
Q
L
A
L
H
R
S
L
E
P
Q
G
Q
V
Site 38
T738
E
V
H
V
Q
E
E
T
V
G
P
W
R
R
T
Site 39
T745
T
V
G
P
W
R
R
T
L
P
A
E
L
R
A
Site 40
Y838
Q
E
V
V
R
A
F
Y
D
T
L
D
A
A
R
Site 41
T840
V
V
R
A
F
Y
D
T
L
D
A
A
R
S
S
Site 42
S846
D
T
L
D
A
A
R
S
S
I
R
V
V
R
V
Site 43
S847
T
L
D
A
A
R
S
S
I
R
V
V
R
V
E
Site 44
S857
V
V
R
V
E
R
V
S
H
P
L
L
Q
Q
Q
Site 45
Y868
L
Q
Q
Q
Y
E
L
Y
R
E
R
L
L
Q
R
Site 46
Y886
R
P
V
E
Q
V
L
Y
H
G
T
T
A
P
A
Site 47
T912
S
F
C
G
R
N
A
T
V
Y
G
K
G
V
Y
Site 48
Y919
T
V
Y
G
K
G
V
Y
F
A
R
R
A
S
L
Site 49
S925
V
Y
F
A
R
R
A
S
L
S
V
Q
D
R
Y
Site 50
S927
F
A
R
R
A
S
L
S
V
Q
D
R
Y
S
P
Site 51
Y932
S
L
S
V
Q
D
R
Y
S
P
P
N
A
D
G
Site 52
S933
L
S
V
Q
D
R
Y
S
P
P
N
A
D
G
H
Site 53
Y953
A
R
V
L
T
G
D
Y
G
Q
G
R
R
G
L
Site 54
S1011
C
E
H
V
P
R
A
S
P
D
D
P
S
G
L
Site 55
S1016
R
A
S
P
D
D
P
S
G
L
P
G
R
S
P
Site 56
S1022
P
S
G
L
P
G
R
S
P
D
T
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation