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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RFTN2
Full Name:
Raftlin-2
Alias:
FLJ30574; Raftlin family member 2
Type:
Plasma membrane protein
Mass (Da):
55922
Number AA:
501
UniProt ID:
Q52LD8
International Prot ID:
IPI00043747
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
L
E
D
P
D
D
S
S
P
G
K
I
F
S
Site 2
S15
L
E
D
P
D
D
S
S
P
G
K
I
F
S
T
Site 3
S21
S
S
P
G
K
I
F
S
T
L
K
R
P
Q
V
Site 4
T22
S
P
G
K
I
F
S
T
L
K
R
P
Q
V
E
Site 5
T30
L
K
R
P
Q
V
E
T
K
T
E
F
A
Y
E
Site 6
T32
R
P
Q
V
E
T
K
T
E
F
A
Y
E
Y
V
Site 7
Y36
E
T
K
T
E
F
A
Y
E
Y
V
L
L
D
F
Site 8
T44
E
Y
V
L
L
D
F
T
L
Q
A
S
S
N
P
Site 9
Y74
E
N
Y
Y
L
K
G
Y
I
V
G
A
I
H
P
Site 10
S95
Q
R
K
H
L
P
A
S
Y
L
Y
R
V
V
L
Site 11
S112
L
K
L
S
P
K
N
S
A
A
P
S
G
Q
R
Site 12
S116
P
K
N
S
A
A
P
S
G
Q
R
R
P
R
L
Site 13
T131
V
I
E
E
C
P
L
T
S
E
A
Q
T
N
D
Site 14
S162
M
K
F
V
G
F
I
S
Q
H
Y
S
P
S
K
Site 15
Y165
V
G
F
I
S
Q
H
Y
S
P
S
K
F
C
N
Site 16
S166
G
F
I
S
Q
H
Y
S
P
S
K
F
C
N
G
Site 17
S196
G
S
D
E
N
C
R
S
W
N
E
G
T
L
S
Site 18
T201
C
R
S
W
N
E
G
T
L
S
G
Q
S
S
E
Site 19
S203
S
W
N
E
G
T
L
S
G
Q
S
S
E
S
G
Site 20
S207
G
T
L
S
G
Q
S
S
E
S
G
I
E
E
E
Site 21
Y222
L
H
H
E
S
G
Q
Y
Q
M
E
Q
N
G
S
Site 22
S229
Y
Q
M
E
Q
N
G
S
P
T
S
S
K
S
R
Site 23
S233
Q
N
G
S
P
T
S
S
K
S
R
K
G
E
A
Site 24
S235
G
S
P
T
S
S
K
S
R
K
G
E
A
S
D
Site 25
S241
K
S
R
K
G
E
A
S
D
N
K
L
Y
T
V
Site 26
Y246
E
A
S
D
N
K
L
Y
T
V
F
N
A
F
D
Site 27
T247
A
S
D
N
K
L
Y
T
V
F
N
A
F
D
D
Site 28
S258
A
F
D
D
D
S
T
S
W
A
Y
Q
E
G
I
Site 29
Y261
D
D
S
T
S
W
A
Y
Q
E
G
I
L
S
M
Site 30
S267
A
Y
Q
E
G
I
L
S
M
K
V
T
R
K
G
Site 31
S275
M
K
V
T
R
K
G
S
V
I
S
T
L
D
A
Site 32
T279
R
K
G
S
V
I
S
T
L
D
A
D
W
L
E
Site 33
Y291
W
L
E
L
T
T
F
Y
Y
K
Q
G
L
S
L
Site 34
S308
S
F
V
F
W
E
T
S
K
G
E
H
L
P
K
Site 35
S316
K
G
E
H
L
P
K
S
L
E
G
F
F
I
Y
Site 36
Y323
S
L
E
G
F
F
I
Y
E
E
E
G
S
G
V
Site 37
S328
F
I
Y
E
E
E
G
S
G
V
P
G
S
S
R
Site 38
S333
E
G
S
G
V
P
G
S
S
R
K
G
N
D
A
Site 39
S334
G
S
G
V
P
G
S
S
R
K
G
N
D
A
I
Site 40
T356
I
E
G
C
E
I
K
T
D
Y
G
P
L
L
H
Site 41
Y358
G
C
E
I
K
T
D
Y
G
P
L
L
H
T
L
Site 42
S385
T
P
V
L
R
H
D
S
E
G
N
L
A
T
K
Site 43
T391
D
S
E
G
N
L
A
T
K
Q
I
V
F
L
Q
Site 44
S405
Q
R
P
V
M
W
N
S
A
A
Q
T
P
D
K
Site 45
T409
M
W
N
S
A
A
Q
T
P
D
K
K
A
S
R
Site 46
T427
G
E
D
K
N
K
A
T
S
R
S
I
G
L
D
Site 47
S430
K
N
K
A
T
S
R
S
I
G
L
D
T
T
S
Site 48
T435
S
R
S
I
G
L
D
T
T
S
S
Q
P
A
E
Site 49
T436
R
S
I
G
L
D
T
T
S
S
Q
P
A
E
S
Site 50
S437
S
I
G
L
D
T
T
S
S
Q
P
A
E
S
R
Site 51
S438
I
G
L
D
T
T
S
S
Q
P
A
E
S
R
H
Site 52
S443
T
S
S
Q
P
A
E
S
R
H
L
P
E
E
C
Site 53
S453
L
P
E
E
C
R
L
S
P
S
R
E
C
W
T
Site 54
S470
G
R
L
A
Q
H
N
S
F
S
G
F
S
S
S
Site 55
S472
L
A
Q
H
N
S
F
S
G
F
S
S
S
D
N
Site 56
S476
N
S
F
S
G
F
S
S
S
D
N
V
L
R
E
Site 57
S477
S
F
S
G
F
S
S
S
D
N
V
L
R
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation