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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TIGD2
Full Name:
Tigger transposable element-derived protein 2
Alias:
dkfzp667d1322; tigd2; tigger transposable element derived 2
Type:
Mass (Da):
59623
Number AA:
525
UniProt ID:
Q4W5G0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
K
K
L
E
E
G
I
S
F
K
K
L
S
V
V
Site 2
S40
V
V
Y
G
I
G
E
S
T
V
R
D
I
K
K
Site 3
T41
V
Y
G
I
G
E
S
T
V
R
D
I
K
K
N
Site 4
Y55
N
K
E
R
I
I
N
Y
A
N
S
S
D
P
T
Site 5
S58
R
I
I
N
Y
A
N
S
S
D
P
T
S
G
V
Site 6
S59
I
I
N
Y
A
N
S
S
D
P
T
S
G
V
S
Site 7
T62
Y
A
N
S
S
D
P
T
S
G
V
S
K
R
K
Site 8
S63
A
N
S
S
D
P
T
S
G
V
S
K
R
K
S
Site 9
S66
S
D
P
T
S
G
V
S
K
R
K
S
M
K
S
Site 10
S70
S
G
V
S
K
R
K
S
M
K
S
S
T
Y
E
Site 11
S73
S
K
R
K
S
M
K
S
S
T
Y
E
E
L
D
Site 12
S74
K
R
K
S
M
K
S
S
T
Y
E
E
L
D
R
Site 13
T92
E
W
F
N
Q
Q
K
T
D
G
I
P
V
S
G
Site 14
S98
K
T
D
G
I
P
V
S
G
T
I
C
A
K
Q
Site 15
T100
D
G
I
P
V
S
G
T
I
C
A
K
Q
A
K
Site 16
S123
E
G
D
F
N
A
S
S
G
W
L
T
R
F
K
Site 17
T127
N
A
S
S
G
W
L
T
R
F
K
Q
R
H
G
Site 18
T150
T
K
L
K
G
D
E
T
A
A
R
E
F
C
G
Site 19
S158
A
A
R
E
F
C
G
S
F
Q
E
F
V
E
K
Site 20
T192
C
L
P
S
R
T
L
T
L
E
T
D
Q
S
T
Site 21
S198
L
T
L
E
T
D
Q
S
T
S
G
C
R
S
S
Site 22
S200
L
E
T
D
Q
S
T
S
G
C
R
S
S
R
E
Site 23
S204
Q
S
T
S
G
C
R
S
S
R
E
R
I
I
I
Site 24
S205
S
T
S
G
C
R
S
S
R
E
R
I
I
I
M
Site 25
T240
K
P
R
A
F
K
G
T
D
L
S
N
L
P
V
Site 26
S243
A
F
K
G
T
D
L
S
N
L
P
V
T
Y
Y
Site 27
T248
D
L
S
N
L
P
V
T
Y
Y
S
Q
K
G
A
Site 28
Y249
L
S
N
L
P
V
T
Y
Y
S
Q
K
G
A
W
Site 29
Y250
S
N
L
P
V
T
Y
Y
S
Q
K
G
A
W
I
Site 30
Y269
F
R
Q
W
F
E
K
Y
F
V
P
Q
V
Q
K
Site 31
S304
R
P
N
E
E
M
L
S
S
D
D
G
R
I
I
Site 32
S305
P
N
E
E
M
L
S
S
D
D
G
R
I
I
V
Site 33
Y314
D
G
R
I
I
V
K
Y
L
P
P
N
V
T
S
Site 34
S321
Y
L
P
P
N
V
T
S
L
I
Q
P
M
S
Q
Site 35
T333
M
S
Q
G
V
L
A
T
V
K
R
Y
Y
R
A
Site 36
Y338
L
A
T
V
K
R
Y
Y
R
A
G
L
L
Q
K
Site 37
Y346
R
A
G
L
L
Q
K
Y
M
D
E
G
N
D
P
Site 38
S378
R
A
W
N
M
V
K
S
S
T
I
T
K
A
W
Site 39
S379
A
W
N
M
V
K
S
S
T
I
T
K
A
W
K
Site 40
T380
W
N
M
V
K
S
S
T
I
T
K
A
W
K
K
Site 41
T382
M
V
K
S
S
T
I
T
K
A
W
K
K
L
F
Site 42
S434
N
I
D
Q
W
F
D
S
R
S
S
D
S
S
C
Site 43
S436
D
Q
W
F
D
S
R
S
S
D
S
S
C
Q
V
Site 44
S437
Q
W
F
D
S
R
S
S
D
S
S
C
Q
V
L
Site 45
S439
F
D
S
R
S
S
D
S
S
C
Q
V
L
T
D
Site 46
S440
D
S
R
S
S
D
S
S
C
Q
V
L
T
D
S
Site 47
T445
D
S
S
C
Q
V
L
T
D
S
E
S
A
E
D
Site 48
S447
S
C
Q
V
L
T
D
S
E
S
A
E
D
Q
T
Site 49
S449
Q
V
L
T
D
S
E
S
A
E
D
Q
T
K
A
Site 50
S463
A
A
E
Q
K
P
S
S
K
S
R
K
T
E
L
Site 51
S465
E
Q
K
P
S
S
K
S
R
K
T
E
L
N
P
Site 52
T468
P
S
S
K
S
R
K
T
E
L
N
P
E
K
H
Site 53
S477
L
N
P
E
K
H
I
S
H
K
A
A
L
E
W
Site 54
Y491
W
T
E
N
L
L
D
Y
L
E
Q
Q
D
D
M
Site 55
S501
Q
Q
D
D
M
L
L
S
D
K
L
V
L
R
R
Site 56
T511
L
V
L
R
R
L
R
T
I
I
R
K
K
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation