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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANO6
Full Name:
Anoctamin-6
Alias:
TM16F; TMEM16F
Type:
Uncharacterized protein, Integral membrane protein
Mass (Da):
106165
Number AA:
910
UniProt ID:
Q4KMQ2
International Prot ID:
IPI00151710
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034707
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005254
GO:0031404
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S38
T
I
V
P
D
L
G
S
L
E
S
Q
H
D
F
Site 2
S41
P
D
L
G
S
L
E
S
Q
H
D
F
R
T
P
Site 3
T47
E
S
Q
H
D
F
R
T
P
E
F
E
E
F
N
Site 4
S59
E
F
N
G
K
P
D
S
L
F
F
N
D
G
Q
Site 5
Y75
R
I
D
F
V
L
V
Y
E
D
E
S
R
K
E
Site 6
T83
E
D
E
S
R
K
E
T
N
K
K
G
T
N
E
Site 7
Y99
Q
R
R
K
R
Q
A
Y
E
S
N
L
I
C
H
Site 8
S101
R
K
R
Q
A
Y
E
S
N
L
I
C
H
G
L
Site 9
T113
H
G
L
Q
L
E
A
T
R
S
V
L
D
D
K
Site 10
S155
P
N
D
L
K
N
R
S
S
A
F
G
T
L
N
Site 11
S156
N
D
L
K
N
R
S
S
A
F
G
T
L
N
W
Site 12
T160
N
R
S
S
A
F
G
T
L
N
W
F
T
K
V
Site 13
S173
K
V
L
S
V
D
E
S
I
I
K
P
E
Q
E
Site 14
Y195
K
N
R
M
N
D
F
Y
I
V
D
R
D
A
F
Site 15
T207
D
A
F
F
N
P
A
T
R
S
R
I
V
Y
F
Site 16
Y241
R
L
V
N
S
G
I
Y
K
A
A
F
P
L
H
Site 17
S256
D
C
K
F
R
R
Q
S
E
D
P
S
C
P
N
Site 18
S260
R
R
Q
S
E
D
P
S
C
P
N
E
R
Y
L
Site 19
Y266
P
S
C
P
N
E
R
Y
L
L
Y
R
E
W
A
Site 20
Y269
P
N
E
R
Y
L
L
Y
R
E
W
A
H
P
R
Site 21
S277
R
E
W
A
H
P
R
S
I
Y
K
K
Q
P
L
Site 22
Y279
W
A
H
P
R
S
I
Y
K
K
Q
P
L
D
L
Site 23
Y290
P
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Site 24
Y291
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Y
Site 25
T363
P
F
W
K
L
N
I
T
C
E
S
S
K
K
L
Site 26
T409
E
L
E
Y
E
W
D
T
V
E
L
Q
Q
E
E
Site 27
Y422
E
E
Q
A
R
P
E
Y
E
A
R
C
T
H
V
Site 28
T427
P
E
Y
E
A
R
C
T
H
V
V
I
N
E
I
Site 29
Y501
G
T
D
P
I
Q
K
Y
L
T
P
Q
T
A
T
Site 30
T503
D
P
I
Q
K
Y
L
T
P
Q
T
A
T
S
I
Site 31
T542
T
N
F
E
L
P
R
T
Q
T
D
Y
E
N
S
Site 32
T544
F
E
L
P
R
T
Q
T
D
Y
E
N
S
L
T
Site 33
Y546
L
P
R
T
Q
T
D
Y
E
N
S
L
T
M
K
Site 34
Y568
N
Y
Y
S
S
C
F
Y
I
A
F
F
K
G
K
Site 35
Y579
F
K
G
K
F
V
G
Y
P
G
D
P
V
Y
W
Site 36
Y585
G
Y
P
G
D
P
V
Y
W
L
G
K
Y
R
N
Site 37
Y590
P
V
Y
W
L
G
K
Y
R
N
E
E
C
D
P
Site 38
S640
I
G
R
F
H
R
V
S
G
S
E
K
I
T
P
Site 39
S642
R
F
H
R
V
S
G
S
E
K
I
T
P
R
W
Site 40
T646
V
S
G
S
E
K
I
T
P
R
W
E
Q
D
Y
Site 41
Y653
T
P
R
W
E
Q
D
Y
H
L
Q
P
M
G
K
Site 42
T678
I
I
Q
F
G
F
V
T
L
F
V
A
S
F
P
Site 43
S758
P
R
L
V
Y
Y
W
S
F
S
V
P
P
Y
G
Site 44
Y764
W
S
F
S
V
P
P
Y
G
D
H
T
S
Y
T
Site 45
T768
V
P
P
Y
G
D
H
T
S
Y
T
M
E
G
Y
Site 46
Y770
P
Y
G
D
H
T
S
Y
T
M
E
G
Y
I
N
Site 47
Y775
T
S
Y
T
M
E
G
Y
I
N
N
T
L
S
I
Site 48
S798
K
S
K
G
N
P
Y
S
D
L
G
N
H
T
T
Site 49
Y813
C
R
Y
R
D
F
R
Y
P
P
G
H
P
Q
E
Site 50
S860
S
Y
A
I
P
D
V
S
K
R
T
K
S
K
I
Site 51
S865
D
V
S
K
R
T
K
S
K
I
Q
R
E
K
Y
Site 52
Y872
S
K
I
Q
R
E
K
Y
L
T
Q
K
L
L
H
Site 53
T874
I
Q
R
E
K
Y
L
T
Q
K
L
L
H
E
N
Site 54
T887
E
N
H
L
K
D
M
T
K
N
M
G
V
I
A
Site 55
S909
D
N
N
L
R
P
K
S
E
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation