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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC40
Full Name:
Coiled-coil domain-containing protein 40
Alias:
Type:
Mass (Da):
130113
Number AA:
1142
UniProt ID:
Q4G0X9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
G
G
A
A
G
R
S
H
P
E
D
G
S
A
Site 2
S17
R
S
H
P
E
D
G
S
A
S
E
G
E
K
E
Site 3
S29
E
K
E
G
N
N
E
S
H
M
V
S
P
P
E
Site 4
S33
N
N
E
S
H
M
V
S
P
P
E
K
D
D
G
Site 5
S49
K
G
E
E
A
V
G
S
T
E
H
P
E
E
V
Site 6
T58
E
H
P
E
E
V
T
T
Q
A
E
A
A
I
E
Site 7
S85
E
G
E
E
E
A
V
S
Y
G
D
A
E
S
E
Site 8
Y86
G
E
E
E
A
V
S
Y
G
D
A
E
S
E
E
Site 9
S91
V
S
Y
G
D
A
E
S
E
E
E
Y
Y
Y
T
Site 10
Y95
D
A
E
S
E
E
E
Y
Y
Y
T
E
T
S
S
Site 11
Y96
A
E
S
E
E
E
Y
Y
Y
T
E
T
S
S
P
Site 12
Y97
E
S
E
E
E
Y
Y
Y
T
E
T
S
S
P
E
Site 13
T98
S
E
E
E
Y
Y
Y
T
E
T
S
S
P
E
G
Site 14
T100
E
E
Y
Y
Y
T
E
T
S
S
P
E
G
Q
I
Site 15
S102
Y
Y
Y
T
E
T
S
S
P
E
G
Q
I
S
A
Site 16
S108
S
S
P
E
G
Q
I
S
A
A
D
T
T
Y
P
Site 17
T112
G
Q
I
S
A
A
D
T
T
Y
P
Y
F
S
P
Site 18
T113
Q
I
S
A
A
D
T
T
Y
P
Y
F
S
P
P
Site 19
Y114
I
S
A
A
D
T
T
Y
P
Y
F
S
P
P
Q
Site 20
Y116
A
A
D
T
T
Y
P
Y
F
S
P
P
Q
E
L
Site 21
S118
D
T
T
Y
P
Y
F
S
P
P
Q
E
L
P
G
Site 22
Y129
E
L
P
G
E
E
A
Y
D
S
V
S
G
E
A
Site 23
S131
P
G
E
E
A
Y
D
S
V
S
G
E
A
G
L
Site 24
S133
E
E
A
Y
D
S
V
S
G
E
A
G
L
Q
G
Site 25
T146
Q
G
F
Q
Q
E
A
T
G
P
P
E
S
R
E
Site 26
S151
E
A
T
G
P
P
E
S
R
E
R
R
V
T
S
Site 27
T157
E
S
R
E
R
R
V
T
S
P
E
P
S
H
G
Site 28
S158
S
R
E
R
R
V
T
S
P
E
P
S
H
G
V
Site 29
S162
R
V
T
S
P
E
P
S
H
G
V
L
G
P
S
Site 30
S169
S
H
G
V
L
G
P
S
E
Q
M
G
Q
V
T
Site 31
S177
E
Q
M
G
Q
V
T
S
G
P
A
V
G
R
L
Site 32
T185
G
P
A
V
G
R
L
T
G
S
T
E
E
P
Q
Site 33
S187
A
V
G
R
L
T
G
S
T
E
E
P
Q
G
Q
Site 34
T188
V
G
R
L
T
G
S
T
E
E
P
Q
G
Q
V
Site 35
S207
V
Q
H
R
F
R
L
S
H
G
S
D
I
E
S
Site 36
S210
R
F
R
L
S
H
G
S
D
I
E
S
S
D
L
Site 37
S214
S
H
G
S
D
I
E
S
S
D
L
E
E
F
V
Site 38
S215
H
G
S
D
I
E
S
S
D
L
E
E
F
V
S
Site 39
S222
S
D
L
E
E
F
V
S
Q
E
P
V
I
P
P
Site 40
S264
A
M
A
E
R
V
E
S
E
G
S
D
E
E
A
Site 41
S267
E
R
V
E
S
E
G
S
D
E
E
A
E
D
E
Site 42
S276
E
E
A
E
D
E
G
S
Q
L
V
V
L
D
P
Site 43
Y298
F
Q
A
A
L
K
N
Y
L
N
R
Q
I
E
K
Site 44
Y332
Q
E
L
G
V
N
L
Y
E
V
Q
Q
H
L
V
Site 45
S348
L
Q
K
L
L
E
K
S
H
D
R
H
A
M
A
Site 46
S356
H
D
R
H
A
M
A
S
S
E
R
R
Q
K
E
Site 47
S357
D
R
H
A
M
A
S
S
E
R
R
Q
K
E
E
Site 48
T419
R
D
D
I
R
V
M
T
Q
V
V
K
K
A
E
Site 49
Y442
E
K
K
K
Q
D
L
Y
V
D
Q
L
T
T
R
Site 50
T447
D
L
Y
V
D
Q
L
T
T
R
A
Q
Q
L
E
Site 51
S479
R
I
L
R
K
A
V
S
E
A
C
T
E
I
D
Site 52
S489
C
T
E
I
D
A
I
S
V
E
K
R
R
I
M
Site 53
S529
G
C
Q
H
Q
A
K
S
T
D
G
E
I
E
A
Site 54
Y537
T
D
G
E
I
E
A
Y
K
K
S
I
M
K
E
Site 55
S540
E
I
E
A
Y
K
K
S
I
M
K
E
E
E
K
Site 56
T560
S
I
L
N
R
T
E
T
E
A
T
L
L
Q
K
Site 57
T563
N
R
T
E
T
E
A
T
L
L
Q
K
L
T
T
Site 58
S581
T
K
Q
V
A
L
Q
S
Q
F
N
T
Y
R
L
Site 59
T585
A
L
Q
S
Q
F
N
T
Y
R
L
T
L
Q
D
Site 60
T589
Q
F
N
T
Y
R
L
T
L
Q
D
T
E
D
A
Site 61
T593
Y
R
L
T
L
Q
D
T
E
D
A
L
S
Q
D
Site 62
S598
Q
D
T
E
D
A
L
S
Q
D
Q
L
E
Q
M
Site 63
T628
E
L
E
L
R
R
K
T
D
A
A
I
R
E
K
Site 64
T641
E
K
L
Q
E
H
M
T
S
N
K
T
T
K
Y
Site 65
Y648
T
S
N
K
T
T
K
Y
F
N
Q
L
I
L
R
Site 66
T661
L
R
L
Q
K
E
K
T
N
M
M
T
H
L
S
Site 67
T678
N
G
D
I
A
Q
T
T
L
D
I
T
H
T
S
Site 68
T682
A
Q
T
T
L
D
I
T
H
T
S
S
R
L
D
Site 69
T684
T
T
L
D
I
T
H
T
S
S
R
L
D
A
H
Site 70
S685
T
L
D
I
T
H
T
S
S
R
L
D
A
H
Q
Site 71
T694
R
L
D
A
H
Q
K
T
L
V
E
L
D
Q
D
Site 72
T710
K
K
V
N
E
L
I
T
N
S
Q
S
E
I
S
Site 73
S712
V
N
E
L
I
T
N
S
Q
S
E
I
S
R
R
Site 74
S714
E
L
I
T
N
S
Q
S
E
I
S
R
R
T
I
Site 75
S717
T
N
S
Q
S
E
I
S
R
R
T
I
L
I
E
Site 76
T720
Q
S
E
I
S
R
R
T
I
L
I
E
R
K
Q
Site 77
S742
K
Q
L
E
R
M
V
S
E
L
G
G
E
E
V
Site 78
S760
E
L
E
I
K
R
L
S
K
L
I
D
E
H
D
Site 79
S797
E
Q
E
E
Q
L
A
S
L
D
A
S
K
K
E
Site 80
S801
Q
L
A
S
L
D
A
S
K
K
E
L
H
I
M
Site 81
S817
Q
K
K
L
R
V
E
S
K
I
E
Q
E
K
K
Site 82
S853
L
M
N
K
N
R
C
S
S
E
E
L
E
Q
N
Site 83
S854
M
N
K
N
R
C
S
S
E
E
L
E
Q
N
N
Site 84
T864
L
E
Q
N
N
R
V
T
E
N
E
F
V
R
S
Site 85
S871
T
E
N
E
F
V
R
S
L
K
A
S
E
R
E
Site 86
S875
F
V
R
S
L
K
A
S
E
R
E
T
I
K
M
Site 87
T879
L
K
A
S
E
R
E
T
I
K
M
Q
D
K
L
Site 88
S922
Q
L
A
K
E
M
R
S
S
V
D
S
E
I
G
Site 89
S923
L
A
K
E
M
R
S
S
V
D
S
E
I
G
Q
Site 90
S926
E
M
R
S
S
V
D
S
E
I
G
Q
T
E
I
Site 91
T931
V
D
S
E
I
G
Q
T
E
I
R
A
M
K
G
Site 92
T970
L
A
V
A
R
R
E
T
V
T
T
Q
A
E
G
Site 93
T972
V
A
R
R
E
T
V
T
T
Q
A
E
G
Q
R
Site 94
T973
A
R
R
E
T
V
T
T
Q
A
E
G
Q
R
K
Site 95
T987
K
M
D
R
K
A
L
T
R
T
D
F
H
H
K
Site 96
T1009
I
R
D
V
R
K
A
T
D
E
C
T
K
T
V
Site 97
T1015
A
T
D
E
C
T
K
T
V
L
E
L
E
E
T
Site 98
T1022
T
V
L
E
L
E
E
T
Q
R
N
V
S
S
S
Site 99
S1027
E
E
T
Q
R
N
V
S
S
S
L
L
E
K
Q
Site 100
S1028
E
T
Q
R
N
V
S
S
S
L
L
E
K
Q
E
Site 101
S1029
T
Q
R
N
V
S
S
S
L
L
E
K
Q
E
K
Site 102
T1046
V
I
Q
A
D
F
D
T
L
E
A
D
L
T
R
Site 103
T1052
D
T
L
E
A
D
L
T
R
L
G
A
L
K
R
Site 104
Y1083
Q
A
V
K
E
G
R
Y
V
F
L
F
R
S
K
Site 105
Y1118
L
D
R
V
R
D
E
Y
P
Q
F
Q
E
A
L
Site 106
S1138
M
I
A
N
K
L
E
S
P
G
P
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation