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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1432
Full Name:
Protein RIC1 homolog
Alias:
BA207C16.1; CIP150; Connexin 43 interacting protein 150 kDa; Connexin 43-interacting protein of 150 kDa
Type:
Adapter/scaffold protein
Mass (Da):
159301
Number AA:
1423
UniProt ID:
Q4ADV7
International Prot ID:
IPI00164719
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
E
A
P
F
H
V
Q
S
D
P
Q
R
A
F
F
Site 2
Y56
P
S
V
L
I
V
T
Y
K
E
P
A
K
S
S
Site 3
S62
T
Y
K
E
P
A
K
S
S
T
Q
F
G
S
Y
Site 4
S63
Y
K
E
P
A
K
S
S
T
Q
F
G
S
Y
K
Site 5
T64
K
E
P
A
K
S
S
T
Q
F
G
S
Y
K
Q
Site 6
S78
Q
A
E
W
R
P
D
S
T
M
I
A
V
S
T
Site 7
T96
Y
I
L
F
F
H
I
T
S
T
R
G
D
K
Y
Site 8
Y103
T
S
T
R
G
D
K
Y
L
Y
E
P
V
Y
P
Site 9
Y105
T
R
G
D
K
Y
L
Y
E
P
V
Y
P
K
G
Site 10
Y109
K
Y
L
Y
E
P
V
Y
P
K
G
S
P
Q
M
Site 11
S113
E
P
V
Y
P
K
G
S
P
Q
M
K
G
T
P
Site 12
T119
G
S
P
Q
M
K
G
T
P
H
F
K
E
E
Q
Site 13
S187
N
L
C
T
V
P
F
S
V
D
L
Q
S
S
R
Site 14
T231
D
G
K
V
G
F
I
T
P
V
S
S
R
F
T
Site 15
T238
T
P
V
S
S
R
F
T
A
E
Q
L
H
G
V
Site 16
T254
P
Q
D
V
V
D
G
T
C
V
A
V
N
N
K
Site 17
Y277
V
S
G
S
V
Q
V
Y
T
I
D
N
S
T
G
Site 18
T278
S
G
S
V
Q
V
Y
T
I
D
N
S
T
G
A
Site 19
T295
L
S
H
K
L
E
L
T
A
K
Q
Y
P
D
I
Site 20
Y299
L
E
L
T
A
K
Q
Y
P
D
I
W
N
K
T
Site 21
Y350
T
L
G
G
D
F
A
Y
R
S
D
G
T
K
K
Site 22
S352
G
G
D
F
A
Y
R
S
D
G
T
K
K
D
P
Site 23
S364
K
D
P
L
K
I
N
S
M
S
W
G
A
E
G
Site 24
S366
P
L
K
I
N
S
M
S
W
G
A
E
G
Y
H
Site 25
S382
W
V
I
S
G
F
G
S
Q
N
T
E
I
E
S
Site 26
S389
S
Q
N
T
E
I
E
S
D
L
R
S
V
V
K
Site 27
S393
E
I
E
S
D
L
R
S
V
V
K
Q
P
S
I
Site 28
Y431
L
Q
G
E
D
R
L
Y
L
N
C
G
E
A
S
Site 29
S438
Y
L
N
C
G
E
A
S
Q
T
Q
N
P
R
S
Site 30
T440
N
C
G
E
A
S
Q
T
Q
N
P
R
S
S
S
Site 31
S445
S
Q
T
Q
N
P
R
S
S
S
T
H
S
E
H
Site 32
S446
Q
T
Q
N
P
R
S
S
S
T
H
S
E
H
K
Site 33
S447
T
Q
N
P
R
S
S
S
T
H
S
E
H
K
P
Site 34
S450
P
R
S
S
S
T
H
S
E
H
K
P
S
R
E
Site 35
S455
T
H
S
E
H
K
P
S
R
E
K
S
P
F
A
Site 36
S459
H
K
P
S
R
E
K
S
P
F
A
D
G
G
L
Site 37
S472
G
L
E
S
Q
G
L
S
T
L
L
G
H
R
H
Site 38
T473
L
E
S
Q
G
L
S
T
L
L
G
H
R
H
W
Site 39
T488
H
V
V
Q
I
S
S
T
Y
L
E
S
N
W
P
Site 40
S492
I
S
S
T
Y
L
E
S
N
W
P
I
R
F
S
Site 41
S499
S
N
W
P
I
R
F
S
A
I
D
K
L
G
Q
Site 42
Y568
R
Q
E
E
L
R
V
Y
L
R
T
S
N
L
D
Site 43
T571
E
L
R
V
Y
L
R
T
S
N
L
D
N
A
F
Site 44
S572
L
R
V
Y
L
R
T
S
N
L
D
N
A
F
A
Site 45
Y610
A
D
C
S
I
C
L
Y
S
I
E
R
K
S
D
Site 46
S611
D
C
S
I
C
L
Y
S
I
E
R
K
S
D
G
Site 47
S616
L
Y
S
I
E
R
K
S
D
G
P
N
T
T
A
Site 48
T621
R
K
S
D
G
P
N
T
T
A
G
I
Q
V
L
Site 49
Y636
Q
E
V
S
M
S
R
Y
I
P
H
P
F
L
V
Site 50
S670
Q
Q
A
R
G
A
E
S
I
M
L
N
L
A
G
Site 51
S687
I
M
M
Q
R
D
R
S
G
P
Q
I
R
E
K
Site 52
S762
R
D
H
R
K
P
H
S
F
L
S
Q
R
I
M
Site 53
S765
R
K
P
H
S
F
L
S
Q
R
I
M
L
P
F
Site 54
Y777
L
P
F
H
I
N
I
Y
P
L
A
V
L
F
E
Site 55
Y798
A
V
N
D
T
L
L
Y
D
S
L
Y
T
R
N
Site 56
S800
N
D
T
L
L
Y
D
S
L
Y
T
R
N
N
A
Site 57
Y802
T
L
L
Y
D
S
L
Y
T
R
N
N
A
R
E
Site 58
Y827
V
E
R
T
S
Q
I
Y
L
H
H
I
L
R
Q
Site 59
T874
E
V
L
E
E
E
A
T
S
R
E
P
I
P
D
Site 60
S875
V
L
E
E
E
A
T
S
R
E
P
I
P
D
P
Site 61
S987
R
F
L
K
A
I
G
S
G
E
S
E
T
P
P
Site 62
S990
K
A
I
G
S
G
E
S
E
T
P
P
S
T
P
Site 63
T992
I
G
S
G
E
S
E
T
P
P
S
T
P
T
A
Site 64
S995
G
E
S
E
T
P
P
S
T
P
T
A
Q
E
P
Site 65
T996
E
S
E
T
P
P
S
T
P
T
A
Q
E
P
S
Site 66
S1004
P
T
A
Q
E
P
S
S
S
G
G
F
E
F
F
Site 67
S1005
T
A
Q
E
P
S
S
S
G
G
F
E
F
F
R
Site 68
S1015
F
E
F
F
R
N
R
S
I
S
L
S
Q
S
A
Site 69
S1017
F
F
R
N
R
S
I
S
L
S
Q
S
A
E
N
Site 70
S1019
R
N
R
S
I
S
L
S
Q
S
A
E
N
V
P
Site 71
S1021
R
S
I
S
L
S
Q
S
A
E
N
V
P
A
S
Site 72
S1028
S
A
E
N
V
P
A
S
K
F
S
L
Q
K
T
Site 73
S1031
N
V
P
A
S
K
F
S
L
Q
K
T
L
S
M
Site 74
T1035
S
K
F
S
L
Q
K
T
L
S
M
P
S
G
P
Site 75
S1037
F
S
L
Q
K
T
L
S
M
P
S
G
P
S
G
Site 76
S1040
Q
K
T
L
S
M
P
S
G
P
S
G
K
R
W
Site 77
S1043
L
S
M
P
S
G
P
S
G
K
R
W
S
K
D
Site 78
S1048
G
P
S
G
K
R
W
S
K
D
S
D
C
A
E
Site 79
S1132
I
P
A
S
S
I
S
S
P
F
K
N
G
K
Y
Site 80
Y1139
S
P
F
K
N
G
K
Y
R
T
V
G
E
Q
L
Site 81
T1141
F
K
N
G
K
Y
R
T
V
G
E
Q
L
L
K
Site 82
S1149
V
G
E
Q
L
L
K
S
Q
S
A
D
P
F
L
Site 83
S1151
E
Q
L
L
K
S
Q
S
A
D
P
F
L
N
L
Site 84
S1170
G
I
S
N
I
Q
R
S
Q
S
W
L
S
N
I
Site 85
S1172
S
N
I
Q
R
S
Q
S
W
L
S
N
I
G
P
Site 86
S1175
Q
R
S
Q
S
W
L
S
N
I
G
P
T
H
H
Site 87
T1186
P
T
H
H
E
I
D
T
A
S
S
H
G
P
Q
Site 88
S1200
Q
M
Q
D
A
F
L
S
P
L
S
N
K
G
D
Site 89
S1203
D
A
F
L
S
P
L
S
N
K
G
D
E
C
S
Site 90
S1210
S
N
K
G
D
E
C
S
I
G
S
A
T
D
L
Site 91
T1215
E
C
S
I
G
S
A
T
D
L
T
E
S
S
S
Site 92
T1218
I
G
S
A
T
D
L
T
E
S
S
S
M
V
D
Site 93
S1222
T
D
L
T
E
S
S
S
M
V
D
G
D
W
T
Site 94
T1237
M
V
D
E
N
F
S
T
L
S
L
T
Q
S
E
Site 95
S1239
D
E
N
F
S
T
L
S
L
T
Q
S
E
L
E
Site 96
T1241
N
F
S
T
L
S
L
T
Q
S
E
L
E
H
I
Site 97
S1243
S
T
L
S
L
T
Q
S
E
L
E
H
I
S
M
Site 98
S1254
H
I
S
M
E
L
A
S
K
G
P
H
K
S
Q
Site 99
S1260
A
S
K
G
P
H
K
S
Q
V
Q
L
R
Y
L
Site 100
T1326
A
V
D
R
W
A
S
T
D
C
P
G
Y
K
P
Site 101
T1362
P
D
A
F
Q
P
I
T
M
G
K
T
P
E
Q
Site 102
T1366
Q
P
I
T
M
G
K
T
P
E
Q
T
S
P
R
Site 103
S1371
G
K
T
P
E
Q
T
S
P
R
A
E
E
S
R
Site 104
S1377
T
S
P
R
A
E
E
S
R
G
S
S
S
H
G
Site 105
S1380
R
A
E
E
S
R
G
S
S
S
H
G
S
I
P
Site 106
S1381
A
E
E
S
R
G
S
S
S
H
G
S
I
P
Q
Site 107
S1382
E
E
S
R
G
S
S
S
H
G
S
I
P
Q
G
Site 108
S1385
R
G
S
S
S
H
G
S
I
P
Q
G
E
V
G
Site 109
S1393
I
P
Q
G
E
V
G
S
S
N
M
V
S
R
K
Site 110
S1394
P
Q
G
E
V
G
S
S
N
M
V
S
R
K
E
Site 111
S1398
V
G
S
S
N
M
V
S
R
K
E
E
D
T
A
Site 112
T1404
V
S
R
K
E
E
D
T
A
Q
A
E
E
E
E
Site 113
T1417
E
E
P
F
Q
D
G
T
Y
D
C
S
V
S
_
Site 114
Y1418
E
P
F
Q
D
G
T
Y
D
C
S
V
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation