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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRY2
Full Name:
Cryptochrome-2
Alias:
Cryptochrome 2; Photolyase-like
Type:
Cytoplasm, Nucleus protein
Mass (Da):
66947
Number AA:
593
UniProt ID:
Q49AN0
International Prot ID:
IPI00216898
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003913
GO:0000166
GO:0009881
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0018298
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T19
A
P
A
P
A
P
G
T
D
S
A
S
S
V
H
Site 2
S21
A
P
A
P
G
T
D
S
A
S
S
V
H
W
F
Site 3
S23
A
P
G
T
D
S
A
S
S
V
H
W
F
R
K
Site 4
S24
P
G
T
D
S
A
S
S
V
H
W
F
R
K
G
Site 5
S64
D
P
W
F
A
A
S
S
S
V
G
I
N
R
W
Site 6
S65
P
W
F
A
A
S
S
S
V
G
I
N
R
W
R
Site 7
S77
R
W
R
F
L
L
Q
S
L
E
D
L
D
T
S
Site 8
T83
Q
S
L
E
D
L
D
T
S
L
R
K
L
N
S
Site 9
S84
S
L
E
D
L
D
T
S
L
R
K
L
N
S
R
Site 10
S90
T
S
L
R
K
L
N
S
R
L
F
V
V
R
G
Site 11
T116
E
W
G
V
T
R
L
T
F
E
Y
D
S
E
P
Site 12
Y119
V
T
R
L
T
F
E
Y
D
S
E
P
F
G
K
Site 13
S121
R
L
T
F
E
Y
D
S
E
P
F
G
K
E
R
Site 14
T150
V
V
T
E
N
S
H
T
L
Y
D
L
D
R
I
Site 15
Y152
T
E
N
S
H
T
L
Y
D
L
D
R
I
I
E
Site 16
T168
N
G
Q
K
P
P
L
T
Y
K
R
F
Q
A
I
Site 17
S177
K
R
F
Q
A
I
I
S
R
M
E
L
P
K
K
Site 18
S191
K
P
V
G
L
V
T
S
Q
Q
M
E
S
C
R
Site 19
S196
V
T
S
Q
Q
M
E
S
C
R
A
E
I
Q
E
Site 20
T208
I
Q
E
N
H
D
E
T
Y
G
V
P
S
L
E
Site 21
Y209
Q
E
N
H
D
E
T
Y
G
V
P
S
L
E
E
Site 22
S213
D
E
T
Y
G
V
P
S
L
E
E
L
G
F
P
Site 23
Y253
R
K
A
W
V
A
N
Y
E
R
P
R
M
N
A
Site 24
S262
R
P
R
M
N
A
N
S
L
L
A
S
P
T
G
Site 25
S266
N
A
N
S
L
L
A
S
P
T
G
L
S
P
Y
Site 26
Y286
L
S
C
R
L
F
Y
Y
R
L
W
D
L
Y
K
Site 27
Y292
Y
Y
R
L
W
D
L
Y
K
K
V
K
R
N
S
Site 28
S299
Y
K
K
V
K
R
N
S
T
P
P
L
S
L
F
Site 29
T300
K
K
V
K
R
N
S
T
P
P
L
S
L
F
G
Site 30
S304
R
N
S
T
P
P
L
S
L
F
G
Q
L
L
W
Site 31
T441
P
V
G
F
G
R
R
T
D
P
S
G
D
Y
I
Site 32
S444
F
G
R
R
T
D
P
S
G
D
Y
I
R
R
Y
Site 33
Y447
R
T
D
P
S
G
D
Y
I
R
R
Y
L
P
K
Site 34
Y451
S
G
D
Y
I
R
R
Y
L
P
K
L
K
A
F
Site 35
S460
P
K
L
K
A
F
P
S
R
Y
I
Y
E
P
W
Site 36
Y462
L
K
A
F
P
S
R
Y
I
Y
E
P
W
N
A
Site 37
Y464
A
F
P
S
R
Y
I
Y
E
P
W
N
A
P
E
Site 38
S472
E
P
W
N
A
P
E
S
I
Q
K
A
A
K
C
Site 39
Y507
I
E
R
M
K
Q
I
Y
Q
Q
L
S
R
Y
R
Site 40
S511
K
Q
I
Y
Q
Q
L
S
R
Y
R
G
L
C
L
Site 41
S530
P
S
C
V
E
D
L
S
H
P
V
A
E
P
S
Site 42
S537
S
H
P
V
A
E
P
S
S
S
Q
A
G
S
M
Site 43
S538
H
P
V
A
E
P
S
S
S
Q
A
G
S
M
S
Site 44
S539
P
V
A
E
P
S
S
S
Q
A
G
S
M
S
S
Site 45
S543
P
S
S
S
Q
A
G
S
M
S
S
A
G
P
R
Site 46
S545
S
S
Q
A
G
S
M
S
S
A
G
P
R
P
L
Site 47
S546
S
Q
A
G
S
M
S
S
A
G
P
R
P
L
P
Site 48
S554
A
G
P
R
P
L
P
S
G
P
A
S
P
K
R
Site 49
S558
P
L
P
S
G
P
A
S
P
K
R
K
L
E
A
Site 50
S575
E
P
P
G
E
E
L
S
K
R
A
R
V
A
E
Site 51
T585
A
R
V
A
E
L
P
T
P
E
L
P
S
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation