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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NP60
Full Name:
Putative oxidoreductase GLYR1
Alias:
3-hydroxyisobutyrate dehydrogenase-like; Cytokine-like nuclear factor n-pac; Nuclear protein of 60 kDa
Type:
Uncharacterized protein
Mass (Da):
60556
Number AA:
553
UniProt ID:
Q49A26
International Prot ID:
IPI00000155
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0050662
GO:0004616
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0006098
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
V
W
G
K
L
G
R
Y
P
P
W
P
G
K
I
Site 2
Y63
K
V
E
Q
L
K
P
Y
H
A
H
K
E
E
M
Site 3
T99
R
A
K
G
K
D
Q
T
S
S
H
N
S
S
D
Site 4
S100
A
K
G
K
D
Q
T
S
S
H
N
S
S
D
D
Site 5
S101
K
G
K
D
Q
T
S
S
H
N
S
S
D
D
K
Site 6
S104
D
Q
T
S
S
H
N
S
S
D
D
K
N
R
R
Site 7
S105
Q
T
S
S
H
N
S
S
D
D
K
N
R
R
N
Site 8
S113
D
D
K
N
R
R
N
S
S
E
E
R
S
R
P
Site 9
S114
D
K
N
R
R
N
S
S
E
E
R
S
R
P
N
Site 10
S118
R
N
S
S
E
E
R
S
R
P
N
S
G
D
E
Site 11
S122
E
E
R
S
R
P
N
S
G
D
E
K
R
K
L
Site 12
S130
G
D
E
K
R
K
L
S
L
S
E
G
K
V
K
Site 13
S132
E
K
R
K
L
S
L
S
E
G
K
V
K
K
N
Site 14
S148
G
E
G
K
K
R
V
S
S
G
S
S
E
R
G
Site 15
S149
E
G
K
K
R
V
S
S
G
S
S
E
R
G
S
Site 16
S151
K
K
R
V
S
S
G
S
S
E
R
G
S
K
S
Site 17
S152
K
R
V
S
S
G
S
S
E
R
G
S
K
S
P
Site 18
S156
S
G
S
S
E
R
G
S
K
S
P
L
K
R
A
Site 19
S158
S
S
E
R
G
S
K
S
P
L
K
R
A
Q
E
Site 20
S167
L
K
R
A
Q
E
Q
S
P
R
K
R
G
R
P
Site 21
T182
P
K
D
E
K
D
L
T
I
P
E
S
S
T
V
Site 22
S186
K
D
L
T
I
P
E
S
S
T
V
K
G
M
M
Site 23
S187
D
L
T
I
P
E
S
S
T
V
K
G
M
M
A
Site 24
S207
F
K
W
Q
P
T
A
S
E
P
V
K
D
A
D
Site 25
S223
H
F
H
H
F
L
L
S
Q
T
E
K
P
A
V
Site 26
T225
H
H
F
L
L
S
Q
T
E
K
P
A
V
C
Y
Site 27
Y232
T
E
K
P
A
V
C
Y
Q
A
I
T
K
K
L
Site 28
S248
I
C
E
E
E
T
G
S
T
S
I
Q
A
A
D
Site 29
T257
S
I
Q
A
A
D
S
T
A
V
N
G
S
I
T
Site 30
T264
T
A
V
N
G
S
I
T
P
T
D
K
K
I
G
Site 31
T266
V
N
G
S
I
T
P
T
D
K
K
I
G
F
L
Site 32
S280
L
G
L
G
L
M
G
S
G
I
V
S
N
L
L
Site 33
T292
N
L
L
K
M
G
H
T
V
T
V
W
N
R
T
Site 34
T294
L
K
M
G
H
T
V
T
V
W
N
R
T
A
E
Site 35
T316
E
G
A
R
L
G
R
T
P
A
E
V
V
S
T
Site 36
S332
D
I
T
F
A
C
V
S
D
P
K
A
A
K
D
Site 37
S345
K
D
L
V
L
G
P
S
G
V
L
Q
G
I
R
Site 38
Y357
G
I
R
P
G
K
C
Y
V
D
M
S
T
V
D
Site 39
T362
K
C
Y
V
D
M
S
T
V
D
A
D
T
V
T
Site 40
S388
R
F
L
E
A
P
V
S
G
N
Q
Q
L
S
N
Site 41
Y410
A
A
G
D
R
G
L
Y
E
D
C
S
S
C
F
Site 42
Y499
G
N
F
K
P
D
F
Y
L
K
Y
I
Q
K
D
Site 43
Y502
K
P
D
F
Y
L
K
Y
I
Q
K
D
L
R
L
Site 44
T521
G
D
A
V
N
H
P
T
P
M
A
A
A
A
N
Site 45
S540
R
A
K
A
L
D
Q
S
D
N
D
M
S
A
V
Site 46
S545
D
Q
S
D
N
D
M
S
A
V
Y
R
A
Y
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation