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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LONRF3
Full Name:
LON peptidase N-terminal domain and RING finger protein 3
Alias:
RING finger protein 127
Type:
Mass (Da):
84490
Number AA:
759
UniProt ID:
Q496Y0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
L
S
L
P
A
E
V
S
S
D
N
L
E
S
A
Site 2
S18
S
L
P
A
E
V
S
S
D
N
L
E
S
A
E
Site 3
S29
E
S
A
E
R
G
A
S
A
A
Q
V
D
M
G
Site 4
T51
E
G
P
A
P
L
P
T
R
E
P
E
Q
E
Q
Site 5
S59
R
E
P
E
Q
E
Q
S
P
G
T
S
T
P
E
Site 6
T62
E
Q
E
Q
S
P
G
T
S
T
P
E
S
K
V
Site 7
S63
Q
E
Q
S
P
G
T
S
T
P
E
S
K
V
L
Site 8
T64
E
Q
S
P
G
T
S
T
P
E
S
K
V
L
L
Site 9
S67
P
G
T
S
T
P
E
S
K
V
L
L
T
Q
A
Site 10
S94
L
E
V
Y
R
Q
L
S
E
R
Q
Q
L
V
A
Site 11
S130
P
A
P
P
D
E
G
S
T
A
S
G
T
V
A
Site 12
T135
E
G
S
T
A
S
G
T
V
A
A
E
E
T
G
Site 13
S166
R
K
C
H
G
F
L
S
D
P
V
S
L
S
C
Site 14
S244
F
P
G
P
A
R
A
S
Q
L
R
H
E
G
N
Site 15
Y254
R
H
E
G
N
R
L
Y
R
E
R
Q
V
E
A
Site 16
Y280
A
P
N
D
H
L
L
Y
S
N
R
S
Q
I
Y
Site 17
S284
H
L
L
Y
S
N
R
S
Q
I
Y
F
T
L
E
Site 18
Y287
Y
S
N
R
S
Q
I
Y
F
T
L
E
S
H
E
Site 19
Y336
E
A
L
R
E
F
L
Y
C
V
S
L
D
G
K
Site 20
S363
L
E
L
P
H
C
S
S
Q
E
E
A
A
A
R
Site 21
S374
A
A
A
R
G
D
G
S
S
L
M
D
P
A
K
Site 22
S375
A
A
R
G
D
G
S
S
L
M
D
P
A
K
V
Site 23
S405
E
E
K
W
D
A
T
S
P
K
A
A
S
S
K
Site 24
S410
A
T
S
P
K
A
A
S
S
K
T
G
K
C
Q
Site 25
S411
T
S
P
K
A
A
S
S
K
T
G
K
C
Q
E
Site 26
T413
P
K
A
A
S
S
K
T
G
K
C
Q
E
K
K
Site 27
S428
R
K
H
C
Q
I
E
S
Q
E
E
T
G
M
P
Site 28
T432
Q
I
E
S
Q
E
E
T
G
M
P
N
K
A
S
Site 29
T445
A
S
K
Q
D
P
P
T
D
Q
G
D
K
P
A
Site 30
S454
Q
G
D
K
P
A
L
S
L
P
L
A
S
F
D
Site 31
T479
R
L
F
Y
E
P
V
T
T
P
C
G
H
T
F
Site 32
S509
P
L
C
K
D
G
L
S
Q
C
L
A
S
R
K
Site 33
S514
G
L
S
Q
C
L
A
S
R
K
Y
S
K
N
V
Site 34
Y517
Q
C
L
A
S
R
K
Y
S
K
N
V
I
M
E
Site 35
S518
C
L
A
S
R
K
Y
S
K
N
V
I
M
E
E
Site 36
Y542
L
K
E
R
R
K
L
Y
E
E
E
M
E
E
L
Site 37
T589
M
I
R
R
C
I
E
T
G
T
R
Q
F
G
M
Site 38
S625
Q
F
F
A
D
G
R
S
V
V
D
S
I
G
K
Site 39
S629
D
G
R
S
V
V
D
S
I
G
K
R
R
F
R
Site 40
S641
R
F
R
V
L
H
Q
S
Q
R
D
G
Y
N
T
Site 41
Y646
H
Q
S
Q
R
D
G
Y
N
T
A
D
I
E
Y
Site 42
T648
S
Q
R
D
G
Y
N
T
A
D
I
E
Y
I
E
Site 43
Y653
Y
N
T
A
D
I
E
Y
I
E
D
Q
K
V
Q
Site 44
S684
Q
A
S
L
W
F
H
S
L
K
L
S
L
K
N
Site 45
S688
W
F
H
S
L
K
L
S
L
K
N
R
I
L
N
Site 46
S739
L
P
F
L
A
M
R
S
L
K
D
R
L
N
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation