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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC37
Full Name:
Coiled-coil domain-containing protein 37
Alias:
CCD37; coiled-coil domain containing 37; Coiled-coil domain-containing 37; FLJ40083
Type:
Unknown function
Mass (Da):
71120
Number AA:
UniProt ID:
Q494V2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
I
P
S
T
I
V
Site 2
S6
_
_
M
S
E
I
P
S
T
I
V
S
K
N
M
Site 3
T7
_
M
S
E
I
P
S
T
I
V
S
K
N
M
T
Site 4
S10
E
I
P
S
T
I
V
S
K
N
M
T
N
D
K
Site 5
T14
T
I
V
S
K
N
M
T
N
D
K
N
S
L
E
Site 6
S19
N
M
T
N
D
K
N
S
L
E
S
M
N
I
S
Site 7
S22
N
D
K
N
S
L
E
S
M
N
I
S
S
S
S
Site 8
S26
S
L
E
S
M
N
I
S
S
S
S
S
T
E
E
Site 9
S27
L
E
S
M
N
I
S
S
S
S
S
T
E
E
N
Site 10
S28
E
S
M
N
I
S
S
S
S
S
T
E
E
N
P
Site 11
S30
M
N
I
S
S
S
S
S
T
E
E
N
P
K
K
Site 12
T31
N
I
S
S
S
S
S
T
E
E
N
P
K
K
Q
Site 13
S50
E
E
H
G
P
D
P
S
A
N
P
F
H
L
S
Site 14
S75
Q
E
R
N
K
A
L
S
E
R
Q
Q
Q
K
T
Site 15
T82
S
E
R
Q
Q
Q
K
T
M
R
V
H
Q
K
M
Site 16
T90
M
R
V
H
Q
K
M
T
Y
S
S
K
V
S
A
Site 17
Y91
R
V
H
Q
K
M
T
Y
S
S
K
V
S
A
K
Site 18
S92
V
H
Q
K
M
T
Y
S
S
K
V
S
A
K
H
Site 19
S96
M
T
Y
S
S
K
V
S
A
K
H
T
S
L
R
Site 20
T100
S
K
V
S
A
K
H
T
S
L
R
R
Q
L
Q
Site 21
S101
K
V
S
A
K
H
T
S
L
R
R
Q
L
Q
L
Site 22
Y130
H
Q
R
A
F
R
D
Y
T
T
W
K
L
T
L
Site 23
T131
Q
R
A
F
R
D
Y
T
T
W
K
L
T
L
T
Site 24
T132
R
A
F
R
D
Y
T
T
W
K
L
T
L
T
K
Site 25
Y163
R
Q
M
F
L
L
Q
Y
A
L
D
V
K
R
R
Site 26
T177
R
E
I
Q
R
L
E
T
L
A
T
K
E
E
A
Site 27
T180
Q
R
L
E
T
L
A
T
K
E
E
A
R
L
E
Site 28
S192
R
L
E
R
A
E
K
S
L
E
K
D
A
A
L
Site 29
S210
F
V
R
E
N
D
C
S
S
V
Q
A
M
R
A
Site 30
S211
V
R
E
N
D
C
S
S
V
Q
A
M
R
A
A
Site 31
T236
I
L
E
I
R
D
L
T
T
Q
I
V
N
I
K
Site 32
T237
L
E
I
R
D
L
T
T
Q
I
V
N
I
K
S
Site 33
S244
T
Q
I
V
N
I
K
S
E
I
S
R
F
E
D
Site 34
T252
E
I
S
R
F
E
D
T
L
K
H
Y
K
V
Y
Site 35
Y264
K
V
Y
K
D
F
L
Y
K
L
S
P
K
E
W
Site 36
S267
K
D
F
L
Y
K
L
S
P
K
E
W
L
E
E
Site 37
S280
E
E
Q
E
K
K
H
S
F
L
K
K
A
K
E
Site 38
S289
L
K
K
A
K
E
V
S
E
A
S
K
E
S
S
Site 39
S292
A
K
E
V
S
E
A
S
K
E
S
S
V
N
S
Site 40
S295
V
S
E
A
S
K
E
S
S
V
N
S
T
P
G
Site 41
S296
S
E
A
S
K
E
S
S
V
N
S
T
P
G
D
Site 42
S299
S
K
E
S
S
V
N
S
T
P
G
D
K
G
P
Site 43
T300
K
E
S
S
V
N
S
T
P
G
D
K
G
P
G
Site 44
S314
G
I
K
G
K
A
S
S
M
W
A
K
E
G
Q
Site 45
T323
W
A
K
E
G
Q
G
T
K
K
P
W
R
F
L
Site 46
T332
K
P
W
R
F
L
Q
T
M
R
L
G
R
S
P
Site 47
S338
Q
T
M
R
L
G
R
S
P
S
Y
L
S
S
P
Site 48
S340
M
R
L
G
R
S
P
S
Y
L
S
S
P
Q
Q
Site 49
Y341
R
L
G
R
S
P
S
Y
L
S
S
P
Q
Q
G
Site 50
S343
G
R
S
P
S
Y
L
S
S
P
Q
Q
G
S
Q
Site 51
S344
R
S
P
S
Y
L
S
S
P
Q
Q
G
S
Q
P
Site 52
S349
L
S
S
P
Q
Q
G
S
Q
P
S
E
S
S
G
Site 53
S352
P
Q
Q
G
S
Q
P
S
E
S
S
G
G
D
S
Site 54
S354
Q
G
S
Q
P
S
E
S
S
G
G
D
S
R
G
Site 55
S355
G
S
Q
P
S
E
S
S
G
G
D
S
R
G
S
Site 56
S359
S
E
S
S
G
G
D
S
R
G
S
N
S
P
I
Site 57
S362
S
G
G
D
S
R
G
S
N
S
P
I
P
P
T
Site 58
S364
G
D
S
R
G
S
N
S
P
I
P
P
T
Q
E
Site 59
T369
S
N
S
P
I
P
P
T
Q
E
D
T
D
S
D
Site 60
T373
I
P
P
T
Q
E
D
T
D
S
D
G
E
E
P
Site 61
S375
P
T
Q
E
D
T
D
S
D
G
E
E
P
Q
L
Site 62
Y383
D
G
E
E
P
Q
L
Y
F
T
E
P
Q
Q
L
Site 63
S403
E
L
E
E
Q
N
L
S
L
I
Q
N
S
Q
E
Site 64
S408
N
L
S
L
I
Q
N
S
Q
E
T
E
K
T
L
Site 65
T411
L
I
Q
N
S
Q
E
T
E
K
T
L
E
E
L
Site 66
T414
N
S
Q
E
T
E
K
T
L
E
E
L
S
H
T
Site 67
T421
T
L
E
E
L
S
H
T
L
K
H
T
Q
I
R
Site 68
T453
S
I
T
K
E
E
D
T
A
A
E
L
E
L
K
Site 69
S480
Q
Q
D
K
L
L
E
S
L
N
C
K
V
L
D
Site 70
Y489
N
C
K
V
L
D
V
Y
R
H
C
T
G
T
Q
Site 71
T493
L
D
V
Y
R
H
C
T
G
T
Q
Q
E
A
N
Site 72
T495
V
Y
R
H
C
T
G
T
Q
Q
E
A
N
L
G
Site 73
T578
I
K
K
K
R
G
R
T
L
V
C
R
S
R
P
Site 74
S583
G
R
T
L
V
C
R
S
R
P
P
A
H
R
I
Site 75
S594
A
H
R
I
K
Q
Q
S
E
H
T
L
M
D
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation