KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM48B1
Full Name:
Protein FAM48B1
Alias:
f48b1; Fam48b1; Family with sequence similarity 48, member b1
Type:
Uncharacterized protein
Mass (Da):
89431
Number AA:
823
UniProt ID:
Q3ZLR7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
Q
R
P
P
R
R
R
Y
S
P
R
A
G
K
T
Site 2
S29
R
P
P
R
R
R
Y
S
P
R
A
G
K
T
L
Site 3
T35
Y
S
P
R
A
G
K
T
L
Q
E
K
L
Y
D
Site 4
Y41
K
T
L
Q
E
K
L
Y
D
I
Y
V
E
E
C
Site 5
Y44
Q
E
K
L
Y
D
I
Y
V
E
E
C
G
K
E
Site 6
S73
E
K
L
V
R
R
E
S
L
P
C
L
L
V
N
Site 7
Y82
P
C
L
L
V
N
L
Y
P
G
N
Q
G
Y
S
Site 8
Y88
L
Y
P
G
N
Q
G
Y
S
V
M
L
Q
R
E
Site 9
S98
M
L
Q
R
E
D
G
S
F
A
E
T
I
R
L
Site 10
T102
E
D
G
S
F
A
E
T
I
R
L
P
Y
E
E
Site 11
Y107
A
E
T
I
R
L
P
Y
E
E
R
A
L
L
D
Site 12
Y115
E
E
R
A
L
L
D
Y
L
D
A
E
E
L
P
Site 13
S133
G
D
V
L
D
K
A
S
V
N
I
F
H
S
G
Site 14
Y149
V
I
V
E
V
R
D
Y
R
Q
S
S
N
M
Q
Site 15
S152
E
V
R
D
Y
R
Q
S
S
N
M
Q
P
P
G
Site 16
S153
V
R
D
Y
R
Q
S
S
N
M
Q
P
P
G
Y
Site 17
Y160
S
N
M
Q
P
P
G
Y
Q
S
R
H
I
L
L
Site 18
T170
R
H
I
L
L
R
P
T
M
Q
T
L
A
H
D
Site 19
T173
L
L
R
P
T
M
Q
T
L
A
H
D
V
K
M
Site 20
S189
T
R
D
G
Q
K
W
S
Q
E
D
K
L
Q
L
Site 21
Y225
C
T
A
N
R
L
L
Y
N
K
Q
K
M
N
T
Site 22
Y242
M
K
R
C
L
Q
R
Y
S
W
P
S
V
K
P
Site 23
S243
K
R
C
L
Q
R
Y
S
W
P
S
V
K
P
Q
Site 24
S246
L
Q
R
Y
S
W
P
S
V
K
P
Q
Q
E
Q
Site 25
S254
V
K
P
Q
Q
E
Q
S
D
C
P
P
P
P
E
Site 26
S265
P
P
P
E
L
R
V
S
T
S
G
Q
K
E
E
Site 27
T266
P
P
E
L
R
V
S
T
S
G
Q
K
E
E
R
Site 28
S267
P
E
L
R
V
S
T
S
G
Q
K
E
E
R
K
Site 29
S288
L
N
I
A
K
A
G
S
C
V
D
T
W
K
G
Site 30
T292
K
A
G
S
C
V
D
T
W
K
G
R
P
C
D
Site 31
S317
K
L
A
K
G
Y
Q
S
V
T
A
A
D
P
Q
Site 32
S357
T
K
P
S
I
M
Q
S
F
N
D
P
L
L
C
Site 33
S377
R
K
K
A
R
Q
K
S
Q
K
S
P
W
Q
P
Site 34
S380
A
R
Q
K
S
Q
K
S
P
W
Q
P
F
P
D
Site 35
S390
Q
P
F
P
D
D
H
S
A
C
L
R
P
G
S
Site 36
S397
S
A
C
L
R
P
G
S
E
T
D
A
G
R
A
Site 37
T399
C
L
R
P
G
S
E
T
D
A
G
R
A
V
S
Site 38
S406
T
D
A
G
R
A
V
S
Q
A
Q
E
S
V
Q
Site 39
S411
A
V
S
Q
A
Q
E
S
V
Q
S
K
V
K
G
Site 40
S414
Q
A
Q
E
S
V
Q
S
K
V
K
G
P
G
K
Site 41
S423
V
K
G
P
G
K
M
S
H
S
S
S
G
P
A
Site 42
S425
G
P
G
K
M
S
H
S
S
S
G
P
A
S
V
Site 43
S426
P
G
K
M
S
H
S
S
S
G
P
A
S
V
S
Site 44
S427
G
K
M
S
H
S
S
S
G
P
A
S
V
S
Q
Site 45
S431
H
S
S
S
G
P
A
S
V
S
Q
L
S
S
W
Site 46
S433
S
S
G
P
A
S
V
S
Q
L
S
S
W
K
T
Site 47
S436
P
A
S
V
S
Q
L
S
S
W
K
T
P
E
Q
Site 48
S437
A
S
V
S
Q
L
S
S
W
K
T
P
E
Q
P
Site 49
T440
S
Q
L
S
S
W
K
T
P
E
Q
P
D
P
V
Site 50
S452
D
P
V
W
V
Q
S
S
V
S
G
K
G
E
K
Site 51
T465
E
K
H
P
P
P
R
T
Q
L
P
S
S
S
G
Site 52
S469
P
P
R
T
Q
L
P
S
S
S
G
K
I
S
S
Site 53
S470
P
R
T
Q
L
P
S
S
S
G
K
I
S
S
G
Site 54
S471
R
T
Q
L
P
S
S
S
G
K
I
S
S
G
N
Site 55
S475
P
S
S
S
G
K
I
S
S
G
N
S
F
P
P
Site 56
S476
S
S
S
G
K
I
S
S
G
N
S
F
P
P
Q
Site 57
S479
G
K
I
S
S
G
N
S
F
P
P
Q
Q
A
G
Site 58
S487
F
P
P
Q
Q
A
G
S
P
L
K
P
A
A
P
Site 59
S499
A
A
P
A
A
A
A
S
A
A
P
S
H
S
Q
Site 60
S503
A
A
A
S
A
A
P
S
H
S
Q
K
P
S
V
Site 61
S505
A
S
A
A
P
S
H
S
Q
K
P
S
V
P
L
Site 62
S509
P
S
H
S
Q
K
P
S
V
P
L
I
Q
A
S
Site 63
T542
I
Q
L
R
T
G
S
T
G
L
K
A
I
N
V
Site 64
S562
G
A
Q
A
L
G
S
S
F
K
P
V
Q
A
P
Site 65
S571
K
P
V
Q
A
P
G
S
G
A
P
A
P
A
G
Site 66
S580
A
P
A
P
A
G
I
S
G
S
D
L
Q
S
S
Site 67
S582
A
P
A
G
I
S
G
S
D
L
Q
S
S
G
G
Site 68
S586
I
S
G
S
D
L
Q
S
S
G
G
P
L
P
D
Site 69
S587
S
G
S
D
L
Q
S
S
G
G
P
L
P
D
A
Site 70
T613
P
L
Q
F
F
L
N
T
P
E
G
L
R
P
L
Site 71
T621
P
E
G
L
R
P
L
T
L
L
Q
V
P
Q
G
Site 72
T633
P
Q
G
S
A
V
L
T
G
P
Q
Q
Q
S
H
Site 73
S644
Q
Q
S
H
Q
L
V
S
L
Q
Q
L
Q
Q
P
Site 74
S664
P
Q
P
G
P
Q
G
S
A
L
G
L
S
T
Q
Site 75
S669
Q
G
S
A
L
G
L
S
T
Q
G
Q
A
F
P
Site 76
T686
Q
L
L
K
V
N
P
T
R
A
R
S
G
L
Q
Site 77
S690
V
N
P
T
R
A
R
S
G
L
Q
P
Q
P
Q
Site 78
S749
P
R
Q
E
Q
P
Q
S
Q
Q
Q
Q
P
Q
H
Site 79
T819
Q
R
K
E
G
K
P
T
P
P
A
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation