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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TIMM50
Full Name:
Mitochondrial import inner membrane translocase subunit TIM50
Alias:
Import inner membrane translocase subunit TIM50, mitochondrial; TIM50
Type:
Protein phosphatase, dual-specificity
Mass (Da):
39646
Number AA:
353
UniProt ID:
Q3ZCQ8
International Prot ID:
IPI00656071
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005744
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0004722
PhosphoSite+
KinaseNET
Biological Process:
GO:0007006
GO:0006470
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
A
S
A
A
V
F
S
R
L
Site 2
S9
A
A
S
A
A
V
F
S
R
L
R
S
G
L
R
Site 3
S13
A
V
F
S
R
L
R
S
G
L
R
L
G
S
R
Site 4
S19
R
S
G
L
R
L
G
S
R
G
L
C
T
R
L
Site 5
T24
L
G
S
R
G
L
C
T
R
L
A
T
P
P
R
Site 6
T28
G
L
C
T
R
L
A
T
P
P
R
R
A
P
D
Site 7
S45
A
E
I
G
S
R
G
S
T
K
A
Q
G
P
Q
Site 8
T46
E
I
G
S
R
G
S
T
K
A
Q
G
P
Q
Q
Site 9
S57
G
P
Q
Q
Q
P
G
S
E
G
P
S
Y
A
K
Site 10
S61
Q
P
G
S
E
G
P
S
Y
A
K
K
V
A
L
Site 11
Y62
P
G
S
E
G
P
S
Y
A
K
K
V
A
L
W
Site 12
T115
L
V
Q
Q
L
R
R
T
Y
K
Y
F
K
D
Y
Site 13
Y116
V
Q
Q
L
R
R
T
Y
K
Y
F
K
D
Y
R
Site 14
Y118
Q
L
R
R
T
Y
K
Y
F
K
D
Y
R
Q
M
Site 15
Y122
T
Y
K
Y
F
K
D
Y
R
Q
M
I
I
E
P
Site 16
Y143
P
D
P
L
Q
E
P
Y
Y
Q
P
P
Y
T
L
Site 17
Y144
D
P
L
Q
E
P
Y
Y
Q
P
P
Y
T
L
V
Site 18
Y148
E
P
Y
Y
Q
P
P
Y
T
L
V
L
E
L
T
Site 19
T149
P
Y
Y
Q
P
P
Y
T
L
V
L
E
L
T
G
Site 20
T179
K
K
R
P
G
I
E
T
L
F
Q
Q
L
A
P
Site 21
S215
V
D
P
H
G
F
I
S
Y
R
L
F
R
D
A
Site 22
Y225
L
F
R
D
A
T
R
Y
M
D
G
H
H
V
K
Site 23
Y259
E
A
F
R
L
Q
P
Y
N
G
V
A
L
R
P
Site 24
S271
L
R
P
W
D
G
N
S
D
D
R
V
L
L
D
Site 25
T296
N
G
V
E
D
V
R
T
V
L
E
H
Y
A
L
Site 26
S316
A
A
F
K
Q
R
Q
S
R
L
E
Q
E
E
Q
Site 27
S330
Q
Q
R
L
A
E
L
S
K
S
N
K
Q
N
L
Site 28
S332
R
L
A
E
L
S
K
S
N
K
Q
N
L
F
L
Site 29
S341
K
Q
N
L
F
L
G
S
L
T
S
R
L
W
P
Site 30
T343
N
L
F
L
G
S
L
T
S
R
L
W
P
R
S
Site 31
S344
L
F
L
G
S
L
T
S
R
L
W
P
R
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation