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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBRG1
Full Name:
Transforming growth factor beta regulator 1
Alias:
Nuclear interactor of ARF and Mdm2
Type:
Mass (Da):
44928
Number AA:
411
UniProt ID:
Q3YBR2
International Prot ID:
IPI00431454
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006259
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
L
L
D
G
L
A
S
Site 2
S9
S
L
L
D
G
L
A
S
S
P
R
A
P
L
Q
Site 3
S10
L
L
D
G
L
A
S
S
P
R
A
P
L
Q
S
Site 4
S17
S
P
R
A
P
L
Q
S
S
K
A
R
M
K
K
Site 5
S18
P
R
A
P
L
Q
S
S
K
A
R
M
K
K
L
Site 6
S29
M
K
K
L
P
K
K
S
Q
N
E
K
Y
R
L
Site 7
Y34
K
K
S
Q
N
E
K
Y
R
L
K
Y
L
R
L
Site 8
Y38
N
E
K
Y
R
L
K
Y
L
R
L
R
K
A
A
Site 9
Y75
K
A
K
E
E
R
R
Y
L
L
K
K
L
L
Q
Site 10
S97
E
V
Q
A
A
A
P
S
H
S
S
S
L
P
L
Site 11
S99
Q
A
A
A
P
S
H
S
S
S
L
P
L
T
Y
Site 12
S101
A
A
P
S
H
S
S
S
L
P
L
T
Y
G
V
Site 13
S122
I
Q
G
A
G
P
I
S
G
P
S
T
G
A
E
Site 14
S125
A
G
P
I
S
G
P
S
T
G
A
E
E
P
F
Site 15
T126
G
P
I
S
G
P
S
T
G
A
E
E
P
F
G
Site 16
T200
Y
S
L
G
E
I
I
T
D
R
P
G
F
H
D
Site 17
S209
R
P
G
F
H
D
E
S
A
I
Y
P
V
G
Y
Site 18
Y212
F
H
D
E
S
A
I
Y
P
V
G
Y
C
S
T
Site 19
Y222
G
Y
C
S
T
R
I
Y
A
S
M
K
C
P
D
Site 20
Y234
C
P
D
Q
K
C
L
Y
T
C
Q
I
K
D
G
Site 21
S262
P
Q
N
A
I
V
S
S
S
A
D
A
C
H
A
Site 22
T274
C
H
A
E
L
L
R
T
I
S
T
T
M
G
K
Site 23
Y317
G
A
R
K
C
I
N
Y
Q
W
V
K
F
D
V
Site 24
S344
P
E
N
D
A
A
M
S
F
E
A
F
Q
R
Q
Site 25
S365
N
D
P
L
L
P
G
S
L
D
L
P
E
L
Q
Site 26
Y380
P
A
A
F
V
S
S
Y
Q
P
M
Y
L
T
H
Site 27
Y384
V
S
S
Y
Q
P
M
Y
L
T
H
E
P
L
V
Site 28
T386
S
Y
Q
P
M
Y
L
T
H
E
P
L
V
D
T
Site 29
S400
T
H
L
Q
H
L
K
S
P
S
Q
G
S
P
I
Site 30
S402
L
Q
H
L
K
S
P
S
Q
G
S
P
I
Q
S
Site 31
S405
L
K
S
P
S
Q
G
S
P
I
Q
S
S
D
_
Site 32
S410
Q
G
S
P
I
Q
S
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation