PhosphoNET

           
Protein Info 
   
Short Name:  KRT71
Full Name:  Keratin, type II cytoskeletal 71
Alias:  Cytokeratin-71; K2C71; K6IRS1; Keratin 6 irs; Keratin 71; KRT6IRS; KRT6IRS1
Type:  Keratin filament protein
Mass (Da):  57249
Number AA:  523
UniProt ID:  Q3SY84
International Prot ID:  IPI00061200
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005882  GO:0044422  GO:0044424 Uniprot OncoNet
Molecular Function:  GO:0005198     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9SRQFTCKSGAAAKGG
Site 2S28SAVLSGGSSSSFRAG
Site 3S29AVLSGGSSSSFRAGS
Site 4S30VLSGGSSSSFRAGSK
Site 5S31LSGGSSSSFRAGSKG
Site 6S36SSSFRAGSKGLSGGF
Site 7S40RAGSKGLSGGFGSRS
Site 8S45GLSGGFGSRSLYSLG
Site 9S47SGGFGSRSLYSLGGV
Site 10Y49GFGSRSLYSLGGVRS
Site 11S50FGSRSLYSLGGVRSL
Site 12S56YSLGGVRSLNVASGS
Site 13S61VRSLNVASGSGKSGG
Site 14S63SLNVASGSGKSGGYG
Site 15S66VASGSGKSGGYGFGR
Site 16Y69GSGKSGGYGFGRGRA
Site 17S77GFGRGRASGFAGSMF
Site 18S143ALNNKFASFIDKVRF
Site 19S186PILEGYISNLRKQLE
Site 20T194NLRKQLETLSGDRVR
Site 21S196RKQLETLSGDRVRLD
Site 22S204GDRVRLDSELRNVRD
Site 23Y216VRDVVEDYKKRYEEE
Site 24T228EEEINKRTAAENEFV
Site 25Y245KKDVDAAYANKVELQ
Site 26S278AEITQIQSHISDMSV
Site 27S284QSHISDMSVILSMDN
Site 28S288SDMSVILSMDNNRNL
Site 29S299NRNLDLDSIIDEVRT
Site 30Y308IDEVRTQYEEIALKS
Site 31Y323KAEAEALYQTKFQEL
Site 32T325EAEALYQTKFQELQL
Site 33S349KNTKNEISELTRLIQ
Site 34S360RLIQRIRSEIENVKK
Site 35S370ENVKKQASNLETAIA
Site 36Y415LARMLREYQELMSLK
Site 37S420REYQELMSLKLALDM
Site 38T431ALDMEIATYRKLLES
Site 39Y432LDMEIATYRKLLESE
Site 40S438TYRKLLESEECRMSG
Site 41S444ESEECRMSGEFPSPV
Site 42T459SISIISSTSGGSGYG
Site 43Y465STSGGSGYGFRPSMV
Site 44S470SGYGFRPSMVSGGYV
Site 45S473GFRPSMVSGGYVANS
Site 46Y476PSMVSGGYVANSSNC
Site 47S489NCISGVCSVRGGEGR
Site 48S500GEGRSRGSANDYKDT
Site 49Y504SRGSANDYKDTLGKG
Site 50T507SANDYKDTLGKGSSL
Site 51S512KDTLGKGSSLSAPSK
Site 52S513DTLGKGSSLSAPSKK
Site 53S515LGKGSSLSAPSKKTS
Site 54S518GSSLSAPSKKTSR__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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