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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALDH1L2
Full Name:
Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
Alias:
Aldehyde dehydrogenase family 1 member L2
Type:
Mass (Da):
101746
Number AA:
923
UniProt ID:
Q3SY69
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
L
R
R
G
S
Q
A
L
R
R
F
S
Site 2
S13
S
Q
A
L
R
R
F
S
T
G
R
V
Y
F
K
Site 3
T14
Q
A
L
R
R
F
S
T
G
R
V
Y
F
K
N
Site 4
Y18
R
F
S
T
G
R
V
Y
F
K
N
K
L
K
L
Site 5
T73
L
A
A
E
K
D
G
T
P
V
F
K
L
P
K
Site 6
T87
K
W
R
V
K
G
K
T
I
K
E
V
A
E
A
Site 7
S97
E
V
A
E
A
Y
R
S
V
G
A
E
L
N
V
Site 8
S124
I
D
S
P
K
H
G
S
I
I
Y
H
P
S
I
Site 9
Y127
P
K
H
G
S
I
I
Y
H
P
S
I
L
P
R
Site 10
S130
G
S
I
I
Y
H
P
S
I
L
P
R
H
R
G
Site 11
S139
L
P
R
H
R
G
A
S
A
I
N
W
T
L
I
Site 12
T165
W
A
D
D
G
L
D
T
G
P
I
L
L
Q
R
Site 13
T181
C
D
V
E
P
N
D
T
V
D
A
L
Y
N
R
Site 14
Y186
N
D
T
V
D
A
L
Y
N
R
F
L
F
P
E
Site 15
T221
P
Q
P
E
E
G
A
T
Y
E
G
I
Q
K
K
Site 16
Y222
Q
P
E
E
G
A
T
Y
E
G
I
Q
K
K
E
Site 17
Y267
N
G
Q
M
V
T
F
Y
G
S
T
L
L
N
S
Site 18
S274
Y
G
S
T
L
L
N
S
S
V
P
P
G
E
P
Site 19
S275
G
S
T
L
L
N
S
S
V
P
P
G
E
P
L
Site 20
T309
G
N
D
G
K
A
L
T
V
R
N
L
Q
F
E
Site 21
S324
D
G
K
M
I
P
A
S
Q
Y
F
S
T
G
E
Site 22
Y326
K
M
I
P
A
S
Q
Y
F
S
T
G
E
T
S
Site 23
T332
Q
Y
F
S
T
G
E
T
S
V
V
E
L
T
A
Site 24
S333
Y
F
S
T
G
E
T
S
V
V
E
L
T
A
E
Site 25
S365
N
V
P
I
I
E
D
S
T
D
F
F
K
S
G
Site 26
T366
V
P
I
I
E
D
S
T
D
F
F
K
S
G
A
Site 27
S371
D
S
T
D
F
F
K
S
G
A
S
S
M
D
V
Site 28
S375
F
F
K
S
G
A
S
S
M
D
V
A
R
L
V
Site 29
Y400
Q
L
Q
N
E
D
V
Y
M
A
T
K
F
E
G
Site 30
Y429
E
V
E
L
V
V
D
Y
I
S
K
E
V
N
E
Site 31
T459
T
D
A
D
D
G
K
T
Y
D
T
I
N
P
T
Site 32
Y460
D
A
D
D
G
K
T
Y
D
T
I
N
P
T
D
Site 33
T462
D
D
G
K
T
Y
D
T
I
N
P
T
D
G
S
Site 34
T470
I
N
P
T
D
G
S
T
I
C
K
V
S
Y
A
Site 35
Y511
R
E
R
G
R
L
M
Y
R
L
A
D
L
L
E
Site 36
T526
E
N
Q
E
E
L
A
T
I
E
A
L
D
S
G
Site 37
T550
H
I
G
M
S
V
Q
T
F
R
Y
F
A
G
W
Site 38
T578
A
R
P
N
R
N
L
T
F
T
K
K
E
P
L
Site 39
T580
P
N
R
N
L
T
F
T
K
K
E
P
L
G
V
Site 40
S659
G
I
A
G
Q
R
L
S
E
H
P
D
I
R
K
Site 41
T670
D
I
R
K
L
G
F
T
G
S
T
P
I
G
K
Site 42
S672
R
K
L
G
F
T
G
S
T
P
I
G
K
Q
I
Site 43
T673
K
L
G
F
T
G
S
T
P
I
G
K
Q
I
M
Site 44
S692
V
S
N
L
K
K
V
S
L
E
L
G
G
K
S
Site 45
S739
G
R
L
F
V
E
E
S
I
H
D
E
F
V
T
Site 46
S764
I
G
D
P
L
D
R
S
T
D
H
G
P
Q
N
Site 47
T765
G
D
P
L
D
R
S
T
D
H
G
P
Q
N
H
Site 48
T792
T
G
V
K
E
G
A
T
L
V
Y
G
G
R
Q
Site 49
T810
P
G
F
F
M
E
P
T
V
F
T
D
V
E
D
Site 50
Y818
V
F
T
D
V
E
D
Y
M
Y
L
A
K
E
E
Site 51
Y820
T
D
V
E
D
Y
M
Y
L
A
K
E
E
S
F
Site 52
S850
G
V
L
Q
R
A
N
S
T
E
Y
G
L
A
S
Site 53
Y853
Q
R
A
N
S
T
E
Y
G
L
A
S
G
V
F
Site 54
Y869
R
D
I
N
K
A
M
Y
V
S
E
K
L
E
A
Site 55
S899
P
F
G
G
V
K
Q
S
G
F
G
K
D
L
G
Site 56
Y913
G
E
E
A
L
N
E
Y
L
K
T
K
T
V
T
Site 57
T916
A
L
N
E
Y
L
K
T
K
T
V
T
L
E
Y
Site 58
T918
N
E
Y
L
K
T
K
T
V
T
L
E
Y
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation