KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZIK1
Full Name:
Zinc finger protein interacting with ribonucleoprotein K
Alias:
Zinc finger protein 762
Type:
Mass (Da):
54786
Number AA:
487
UniProt ID:
Q3SY52
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
L
R
A
P
T
Q
V
T
V
S
P
E
T
H
M
Site 2
S15
A
P
T
Q
V
T
V
S
P
E
T
H
M
D
L
Site 3
T23
P
E
T
H
M
D
L
T
K
G
C
V
T
F
E
Site 4
Y35
T
F
E
D
I
A
I
Y
F
S
Q
D
E
W
G
Site 5
S37
E
D
I
A
I
Y
F
S
Q
D
E
W
G
L
L
Site 6
Y52
D
E
A
Q
R
L
L
Y
L
E
V
M
L
E
N
Site 7
T77
H
G
T
E
D
E
E
T
P
S
D
Q
N
V
S
Site 8
S79
T
E
D
E
E
T
P
S
D
Q
N
V
S
V
G
Site 9
S84
T
P
S
D
Q
N
V
S
V
G
V
S
Q
S
K
Site 10
S88
Q
N
V
S
V
G
V
S
Q
S
K
A
G
S
S
Site 11
S90
V
S
V
G
V
S
Q
S
K
A
G
S
S
T
Q
Site 12
S94
V
S
Q
S
K
A
G
S
S
T
Q
K
T
Q
S
Site 13
S95
S
Q
S
K
A
G
S
S
T
Q
K
T
Q
S
C
Site 14
T99
A
G
S
S
T
Q
K
T
Q
S
C
E
M
C
V
Site 15
Y124
D
L
P
G
Q
K
P
Y
L
V
G
E
C
T
N
Site 16
S140
H
Q
H
Q
K
H
H
S
A
K
K
S
L
K
R
Site 17
S144
K
H
H
S
A
K
K
S
L
K
R
D
M
D
R
Site 18
Y154
R
D
M
D
R
A
S
Y
V
K
C
C
L
F
C
Site 19
T196
P
G
G
K
K
P
G
T
I
T
E
C
G
E
D
Site 20
T198
G
K
K
P
G
T
I
T
E
C
G
E
D
I
R
Site 21
S206
E
C
G
E
D
I
R
S
Q
K
S
H
Y
K
S
Site 22
S209
E
D
I
R
S
Q
K
S
H
Y
K
S
G
E
C
Site 23
Y211
I
R
S
Q
K
S
H
Y
K
S
G
E
C
G
K
Site 24
S213
S
Q
K
S
H
Y
K
S
G
E
C
G
K
A
S
Site 25
T225
K
A
S
R
H
K
H
T
P
V
Y
H
P
R
V
Site 26
Y228
R
H
K
H
T
P
V
Y
H
P
R
V
Y
T
G
Site 27
Y233
P
V
Y
H
P
R
V
Y
T
G
K
K
L
Y
E
Site 28
T234
V
Y
H
P
R
V
Y
T
G
K
K
L
Y
E
C
Site 29
Y239
V
Y
T
G
K
K
L
Y
E
C
S
K
C
G
K
Site 30
S242
G
K
K
L
Y
E
C
S
K
C
G
K
A
F
R
Site 31
Y252
G
K
A
F
R
G
K
Y
S
L
V
Q
H
Q
R
Site 32
S253
K
A
F
R
G
K
Y
S
L
V
Q
H
Q
R
V
Site 33
T262
V
Q
H
Q
R
V
H
T
G
E
R
P
W
E
C
Site 34
S277
N
E
C
G
K
F
F
S
Q
T
S
H
L
N
D
Site 35
S280
G
K
F
F
S
Q
T
S
H
L
N
D
H
R
R
Site 36
T290
N
D
H
R
R
I
H
T
G
E
R
P
Y
E
C
Site 37
Y295
I
H
T
G
E
R
P
Y
E
C
S
E
C
G
K
Site 38
S298
G
E
R
P
Y
E
C
S
E
C
G
K
L
F
R
Site 39
S308
G
K
L
F
R
Q
N
S
S
L
V
D
H
Q
K
Site 40
S309
K
L
F
R
Q
N
S
S
L
V
D
H
Q
K
I
Site 41
Y323
I
H
T
G
A
R
P
Y
E
C
S
Q
C
G
K
Site 42
S326
G
A
R
P
Y
E
C
S
Q
C
G
K
S
F
S
Site 43
S331
E
C
S
Q
C
G
K
S
F
S
Q
K
A
T
L
Site 44
S333
S
Q
C
G
K
S
F
S
Q
K
A
T
L
V
K
Site 45
T337
K
S
F
S
Q
K
A
T
L
V
K
H
Q
R
V
Site 46
T346
V
K
H
Q
R
V
H
T
G
E
R
P
Y
K
C
Site 47
Y351
V
H
T
G
E
R
P
Y
K
C
G
E
C
G
N
Site 48
S359
K
C
G
E
C
G
N
S
F
S
Q
S
A
I
L
Site 49
S361
G
E
C
G
N
S
F
S
Q
S
A
I
L
N
Q
Site 50
S363
C
G
N
S
F
S
Q
S
A
I
L
N
Q
H
R
Site 51
T374
N
Q
H
R
R
I
H
T
G
A
K
P
Y
E
C
Site 52
Y379
I
H
T
G
A
K
P
Y
E
C
G
Q
C
G
K
Site 53
S387
E
C
G
Q
C
G
K
S
F
S
Q
K
A
T
L
Site 54
S389
G
Q
C
G
K
S
F
S
Q
K
A
T
L
I
K
Site 55
T393
K
S
F
S
Q
K
A
T
L
I
K
H
Q
R
V
Site 56
T402
I
K
H
Q
R
V
H
T
G
E
R
P
Y
K
C
Site 57
Y407
V
H
T
G
E
R
P
Y
K
C
G
D
C
G
K
Site 58
S415
K
C
G
D
C
G
K
S
F
S
Q
S
S
I
L
Site 59
S417
G
D
C
G
K
S
F
S
Q
S
S
I
L
I
Q
Site 60
S419
C
G
K
S
F
S
Q
S
S
I
L
I
Q
H
R
Site 61
S420
G
K
S
F
S
Q
S
S
I
L
I
Q
H
R
R
Site 62
T430
I
Q
H
R
R
I
H
T
G
A
R
P
Y
E
C
Site 63
Y435
I
H
T
G
A
R
P
Y
E
C
G
Q
C
G
K
Site 64
S443
E
C
G
Q
C
G
K
S
F
S
Q
K
S
G
L
Site 65
S445
G
Q
C
G
K
S
F
S
Q
K
S
G
L
I
Q
Site 66
S448
G
K
S
F
S
Q
K
S
G
L
I
Q
H
Q
V
Site 67
T458
I
Q
H
Q
V
V
H
T
G
E
R
P
Y
E
C
Site 68
Y463
V
H
T
G
E
R
P
Y
E
C
N
K
C
G
N
Site 69
S471
E
C
N
K
C
G
N
S
F
S
Q
C
S
S
L
Site 70
S473
N
K
C
G
N
S
F
S
Q
C
S
S
L
I
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation