KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF528
Full Name:
Zinc finger protein 528
Alias:
ZN528
Type:
Mass (Da):
72138
Number AA:
628
UniProt ID:
Q3MIS6
International Prot ID:
IPI00477799
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
P
A
Q
R
T
L
Y
R
D
V
M
L
E
N
Site 2
Y41
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 3
S46
E
N
Y
R
N
L
V
S
L
G
I
C
L
P
D
Site 4
T68
E
Q
K
R
D
P
W
T
L
Q
S
E
E
K
I
Site 5
T90
E
C
I
K
G
V
N
T
E
R
S
S
K
L
G
Site 6
S93
K
G
V
N
T
E
R
S
S
K
L
G
S
N
A
Site 7
S94
G
V
N
T
E
R
S
S
K
L
G
S
N
A
G
Site 8
S98
E
R
S
S
K
L
G
S
N
A
G
N
K
P
C
Site 9
T112
C
K
N
Q
L
G
F
T
F
Q
L
H
L
S
D
Site 10
S130
F
Q
A
E
R
K
I
S
G
C
K
H
F
E
K
Site 11
S140
K
H
F
E
K
P
V
S
D
N
S
S
V
S
P
Site 12
S143
E
K
P
V
S
D
N
S
S
V
S
P
L
E
K
Site 13
S144
K
P
V
S
D
N
S
S
V
S
P
L
E
K
I
Site 14
S146
V
S
D
N
S
S
V
S
P
L
E
K
I
S
S
Site 15
S152
V
S
P
L
E
K
I
S
S
S
V
K
S
H
L
Site 16
S153
S
P
L
E
K
I
S
S
S
V
K
S
H
L
L
Site 17
S154
P
L
E
K
I
S
S
S
V
K
S
H
L
L
N
Site 18
S157
K
I
S
S
S
V
K
S
H
L
L
N
K
Y
R
Site 19
Y163
K
S
H
L
L
N
K
Y
R
N
N
F
D
H
A
Site 20
Y186
A
H
I
R
E
K
A
Y
K
C
N
E
H
G
Q
Site 21
S198
H
G
Q
V
F
R
A
S
A
S
L
T
N
Q
V
Site 22
T202
F
R
A
S
A
S
L
T
N
Q
V
I
H
N
A
Site 23
Y213
I
H
N
A
D
N
P
Y
K
C
S
E
C
G
K
Site 24
S226
G
K
V
F
S
C
S
S
K
L
V
I
H
R
R
Site 25
T236
V
I
H
R
R
M
H
T
G
E
K
P
Y
K
C
Site 26
Y241
M
H
T
G
E
K
P
Y
K
C
H
E
C
G
K
Site 27
S251
H
E
C
G
K
L
F
S
S
N
S
N
L
S
Q
Site 28
S252
E
C
G
K
L
F
S
S
N
S
N
L
S
Q
H
Site 29
S254
G
K
L
F
S
S
N
S
N
L
S
Q
H
Q
R
Site 30
S257
F
S
S
N
S
N
L
S
Q
H
Q
R
I
H
T
Site 31
T264
S
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 32
S280
E
C
D
K
V
F
R
S
S
S
K
L
A
Q
H
Site 33
S281
C
D
K
V
F
R
S
S
S
K
L
A
Q
H
Q
Site 34
S282
D
K
V
F
R
S
S
S
K
L
A
Q
H
Q
R
Site 35
T292
A
Q
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 36
T320
V
R
H
Q
K
I
H
T
G
E
K
P
Y
S
C
Site 37
S335
N
K
C
G
K
V
F
S
R
H
S
Y
L
A
E
Site 38
S338
G
K
V
F
S
R
H
S
Y
L
A
E
H
Q
T
Site 39
Y339
K
V
F
S
R
H
S
Y
L
A
E
H
Q
T
V
Site 40
T345
S
Y
L
A
E
H
Q
T
V
H
T
G
E
K
P
Site 41
T348
A
E
H
Q
T
V
H
T
G
E
K
P
Y
K
C
Site 42
S363
E
E
C
G
K
A
F
S
V
R
S
S
L
I
T
Site 43
T370
S
V
R
S
S
L
I
T
H
Q
L
I
H
T
G
Site 44
Y381
I
H
T
G
R
K
P
Y
K
C
K
E
C
D
K
Site 45
T404
T
S
H
Q
R
I
H
T
R
E
R
P
Y
G
C
Site 46
Y409
I
H
T
R
E
R
P
Y
G
C
S
Q
C
G
K
Site 47
S412
R
E
R
P
Y
G
C
S
Q
C
G
K
I
F
S
Site 48
S419
S
Q
C
G
K
I
F
S
Q
K
S
D
L
I
R
Site 49
S422
G
K
I
F
S
Q
K
S
D
L
I
R
H
R
K
Site 50
T430
D
L
I
R
H
R
K
T
H
T
D
E
K
P
Y
Site 51
T453
F
R
E
F
S
D
L
T
A
H
F
L
I
H
S
Site 52
Y465
I
H
S
G
E
K
P
Y
E
C
K
E
C
G
K
Site 53
Y476
E
C
G
K
V
F
R
Y
K
S
S
L
T
S
H
Site 54
S478
G
K
V
F
R
Y
K
S
S
L
T
S
H
H
R
Site 55
S479
K
V
F
R
Y
K
S
S
L
T
S
H
H
R
I
Site 56
S482
R
Y
K
S
S
L
T
S
H
H
R
I
H
T
G
Site 57
T488
T
S
H
H
R
I
H
T
G
E
K
P
Y
K
C
Site 58
Y493
I
H
T
G
E
K
P
Y
K
C
N
R
C
G
K
Site 59
S503
N
R
C
G
K
V
F
S
R
S
S
N
L
V
C
Site 60
S505
C
G
K
V
F
S
R
S
S
N
L
V
C
H
Q
Site 61
S506
G
K
V
F
S
R
S
S
N
L
V
C
H
Q
K
Site 62
T516
V
C
H
Q
K
I
H
T
G
E
K
P
Y
K
C
Site 63
S534
G
K
V
F
N
Q
A
S
Y
L
T
R
H
Q
I
Site 64
Y535
K
V
F
N
Q
A
S
Y
L
T
R
H
Q
I
I
Site 65
Y549
I
H
T
G
E
R
P
Y
R
C
S
K
C
G
K
Site 66
S552
G
E
R
P
Y
R
C
S
K
C
G
K
A
F
R
Site 67
T572
T
A
H
L
A
I
H
T
E
K
K
S
H
E
C
Site 68
T587
K
E
C
G
K
I
F
T
Q
K
S
S
L
T
N
Site 69
S590
G
K
I
F
T
Q
K
S
S
L
T
N
H
H
R
Site 70
T608
G
E
K
P
Y
K
C
T
L
C
S
K
V
F
S
Site 71
S615
T
L
C
S
K
V
F
S
H
N
S
D
L
A
Q
Site 72
S618
S
K
V
F
S
H
N
S
D
L
A
Q
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation