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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ITPRIPL2
Full Name:
Inositol 1,4,5-triphosphate receptor-interacting protein-like 2
Alias:
Type:
Mass (Da):
58428
Number AA:
535
UniProt ID:
Q3MIP1
International Prot ID:
IPI00183879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
L
Y
H
V
L
R
G
S
G
G
A
R
A
E
P
Site 2
S78
R
Q
R
F
L
P
G
S
P
R
L
E
G
H
A
Site 3
S88
L
E
G
H
A
A
F
S
S
R
H
F
R
E
P
Site 4
S89
E
G
H
A
A
F
S
S
R
H
F
R
E
P
G
Site 5
S98
H
F
R
E
P
G
L
S
I
L
L
E
S
Y
Y
Site 6
S103
G
L
S
I
L
L
E
S
Y
Y
E
H
E
V
R
Site 7
Y104
L
S
I
L
L
E
S
Y
Y
E
H
E
V
R
L
Site 8
Y105
S
I
L
L
E
S
Y
Y
E
H
E
V
R
L
S
Site 9
S112
Y
E
H
E
V
R
L
S
P
H
V
L
G
H
S
Site 10
S119
S
P
H
V
L
G
H
S
K
A
H
V
S
R
I
Site 11
S139
R
A
G
R
A
R
G
S
P
G
L
I
P
G
G
Site 12
S173
H
K
I
R
R
P
D
S
F
D
V
L
V
P
L
Site 13
S216
C
A
L
K
A
P
P
S
P
S
G
A
S
G
G
Site 14
S218
L
K
A
P
P
S
P
S
G
A
S
G
G
H
W
Site 15
S247
V
R
G
R
R
H
L
S
A
T
L
V
L
R
W
Site 16
T249
G
R
R
H
L
S
A
T
L
V
L
R
W
F
Q
Site 17
S262
F
Q
S
H
L
Q
R
S
L
A
T
V
R
Y
S
Site 18
T265
H
L
Q
R
S
L
A
T
V
R
Y
S
L
E
G
Site 19
S269
S
L
A
T
V
R
Y
S
L
E
G
R
C
R
V
Site 20
T277
L
E
G
R
C
R
V
T
L
T
P
G
G
L
E
Site 21
T279
G
R
C
R
V
T
L
T
P
G
G
L
E
Q
P
Site 22
T288
G
G
L
E
Q
P
P
T
L
H
I
L
P
C
R
Site 23
S331
P
P
P
P
P
L
P
S
A
P
L
L
E
L
P
Site 24
T351
E
A
L
W
G
V
N
T
A
R
Q
E
Q
K
L
Site 25
S392
L
G
A
R
G
L
D
S
A
A
A
T
Q
W
G
Site 26
T396
G
L
D
S
A
A
A
T
Q
W
G
R
I
L
S
Site 27
S498
L
A
A
A
R
L
L
S
T
W
Q
R
L
P
Q
Site 28
T499
A
A
A
R
L
L
S
T
W
Q
R
L
P
Q
L
Site 29
Y510
L
P
Q
L
L
R
A
Y
G
G
P
R
Y
L
A
Site 30
Y515
R
A
Y
G
G
P
R
Y
L
A
R
C
P
P
P
Site 31
S524
A
R
C
P
P
P
R
S
Q
R
T
Q
G
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation