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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAP7D1
Full Name:
MAP7 domain-containing protein 1
Alias:
Arginine/proline rich coiled-coil 1; FLJ10350; FLJ39022; MA7D1; MAP7 domain containing 1; MGC117315; PARCC1; Proline/arginine-rich coiled-coil domain-containing protein 1; RPRC1
Type:
Cytoskeletal protein
Mass (Da):
92820
Number AA:
841
UniProt ID:
Q3KQU3
International Prot ID:
IPI00654605
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005819
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
P
P
A
V
V
A
R
T
P
P
E
P
R
P
S
Site 2
S28
T
P
P
E
P
R
P
S
P
E
G
D
P
S
P
Site 3
S34
P
S
P
E
G
D
P
S
P
P
P
P
P
M
S
Site 4
S41
S
P
P
P
P
P
M
S
A
L
V
P
D
T
P
Site 5
T47
M
S
A
L
V
P
D
T
P
P
D
T
P
P
A
Site 6
T51
V
P
D
T
P
P
D
T
P
P
A
M
K
N
A
Site 7
S70
Q
L
P
L
E
P
E
S
P
S
G
Q
V
G
P
Site 8
S72
P
L
E
P
E
S
P
S
G
Q
V
G
P
R
P
Site 9
S86
P
A
P
P
Q
E
E
S
P
S
S
E
A
K
S
Site 10
S88
P
P
Q
E
E
S
P
S
S
E
A
K
S
R
G
Site 11
S89
P
Q
E
E
S
P
S
S
E
A
K
S
R
G
P
Site 12
S93
S
P
S
S
E
A
K
S
R
G
P
T
P
P
A
Site 13
T97
E
A
K
S
R
G
P
T
P
P
A
M
G
P
R
Site 14
S112
D
A
R
P
P
R
R
S
S
Q
P
S
P
T
A
Site 15
S113
A
R
P
P
R
R
S
S
Q
P
S
P
T
A
V
Site 16
S116
P
R
R
S
S
Q
P
S
P
T
A
V
P
A
S
Site 17
T118
R
S
S
Q
P
S
P
T
A
V
P
A
S
D
S
Site 18
S123
S
P
T
A
V
P
A
S
D
S
P
P
T
K
Q
Site 19
S125
T
A
V
P
A
S
D
S
P
P
T
K
Q
E
V
Site 20
T128
P
A
S
D
S
P
P
T
K
Q
E
V
K
K
A
Site 21
Y152
R
R
E
E
R
A
K
Y
L
A
A
K
K
A
V
Site 22
Y211
L
E
K
N
K
E
R
Y
E
A
A
I
Q
R
S
Site 23
S218
Y
E
A
A
I
Q
R
S
V
K
K
T
W
A
E
Site 24
T222
I
Q
R
S
V
K
K
T
W
A
E
I
R
Q
Q
Site 25
S232
E
I
R
Q
Q
R
W
S
W
A
G
A
L
H
H
Site 26
S240
W
A
G
A
L
H
H
S
S
P
G
H
K
T
S
Site 27
S241
A
G
A
L
H
H
S
S
P
G
H
K
T
S
G
Site 28
T246
H
S
S
P
G
H
K
T
S
G
S
R
C
S
V
Site 29
S247
S
S
P
G
H
K
T
S
G
S
R
C
S
V
S
Site 30
S249
P
G
H
K
T
S
G
S
R
C
S
V
S
A
V
Site 31
S252
K
T
S
G
S
R
C
S
V
S
A
V
N
L
P
Site 32
S254
S
G
S
R
C
S
V
S
A
V
N
L
P
K
H
Site 33
S264
N
L
P
K
H
V
D
S
I
I
N
K
R
L
S
Site 34
S271
S
I
I
N
K
R
L
S
K
S
S
A
T
L
W
Site 35
S273
I
N
K
R
L
S
K
S
S
A
T
L
W
N
S
Site 36
S274
N
K
R
L
S
K
S
S
A
T
L
W
N
S
P
Site 37
T276
R
L
S
K
S
S
A
T
L
W
N
S
P
S
R
Site 38
S280
S
S
A
T
L
W
N
S
P
S
R
N
R
S
L
Site 39
S282
A
T
L
W
N
S
P
S
R
N
R
S
L
Q
L
Site 40
S286
N
S
P
S
R
N
R
S
L
Q
L
S
A
W
E
Site 41
S290
R
N
R
S
L
Q
L
S
A
W
E
S
S
I
V
Site 42
S295
Q
L
S
A
W
E
S
S
I
V
D
R
L
M
T
Site 43
T302
S
I
V
D
R
L
M
T
P
T
L
S
F
L
A
Site 44
S306
R
L
M
T
P
T
L
S
F
L
A
R
S
R
S
Site 45
S313
S
F
L
A
R
S
R
S
A
V
T
L
P
R
N
Site 46
T316
A
R
S
R
S
A
V
T
L
P
R
N
G
R
D
Site 47
T335
C
D
P
G
R
G
P
T
W
G
R
A
G
A
S
Site 48
S342
T
W
G
R
A
G
A
S
L
A
R
G
P
Q
P
Site 49
T352
R
G
P
Q
P
D
R
T
H
P
S
A
A
V
P
Site 50
S355
Q
P
D
R
T
H
P
S
A
A
V
P
V
C
P
Site 51
S364
A
V
P
V
C
P
R
S
A
S
A
S
P
L
T
Site 52
S366
P
V
C
P
R
S
A
S
A
S
P
L
T
P
C
Site 53
S368
C
P
R
S
A
S
A
S
P
L
T
P
C
S
V
Site 54
T371
S
A
S
A
S
P
L
T
P
C
S
V
T
R
S
Site 55
S374
A
S
P
L
T
P
C
S
V
T
R
S
V
H
R
Site 56
S378
T
P
C
S
V
T
R
S
V
H
R
C
A
P
A
Site 57
S399
R
K
P
N
A
G
G
S
P
A
P
V
R
R
R
Site 58
S410
V
R
R
R
P
E
A
S
P
V
Q
K
K
E
K
Site 59
S429
R
E
N
E
K
E
K
S
A
L
A
R
E
R
S
Site 60
S436
S
A
L
A
R
E
R
S
L
K
K
R
Q
S
L
Site 61
S442
R
S
L
K
K
R
Q
S
L
P
A
S
P
R
A
Site 62
S446
K
R
Q
S
L
P
A
S
P
R
A
R
L
S
A
Site 63
S452
A
S
P
R
A
R
L
S
A
S
T
A
S
E
L
Site 64
S454
P
R
A
R
L
S
A
S
T
A
S
E
L
S
P
Site 65
T455
R
A
R
L
S
A
S
T
A
S
E
L
S
P
K
Site 66
S457
R
L
S
A
S
T
A
S
E
L
S
P
K
S
K
Site 67
S460
A
S
T
A
S
E
L
S
P
K
S
K
A
R
P
Site 68
S463
A
S
E
L
S
P
K
S
K
A
R
P
S
S
P
Site 69
S468
P
K
S
K
A
R
P
S
S
P
S
T
S
W
H
Site 70
S469
K
S
K
A
R
P
S
S
P
S
T
S
W
H
R
Site 71
S471
K
A
R
P
S
S
P
S
T
S
W
H
R
P
A
Site 72
T472
A
R
P
S
S
P
S
T
S
W
H
R
P
A
S
Site 73
S473
R
P
S
S
P
S
T
S
W
H
R
P
A
S
P
Site 74
S479
T
S
W
H
R
P
A
S
P
C
P
S
P
G
P
Site 75
S483
R
P
A
S
P
C
P
S
P
G
P
G
H
T
L
Site 76
T489
P
S
P
G
P
G
H
T
L
P
P
K
P
P
S
Site 77
S496
T
L
P
P
K
P
P
S
P
R
G
T
T
A
S
Site 78
T500
K
P
P
S
P
R
G
T
T
A
S
P
K
G
R
Site 79
T501
P
P
S
P
R
G
T
T
A
S
P
K
G
R
V
Site 80
S503
S
P
R
G
T
T
A
S
P
K
G
R
V
R
R
Site 81
S517
K
E
S
A
A
P
A
S
P
A
P
S
P
A
P
Site 82
S519
E
E
A
K
E
S
P
S
A
A
G
P
E
D
K
Site 83
S527
A
A
G
P
E
D
K
S
Q
S
K
R
R
A
S
Site 84
S529
G
P
E
D
K
S
Q
S
K
R
R
A
S
N
E
Site 85
S534
S
Q
S
K
R
R
A
S
N
E
K
E
S
A
A
Site 86
S539
R
A
S
N
E
K
E
S
A
A
P
A
S
P
A
Site 87
S544
K
E
S
A
A
P
A
S
P
A
P
S
P
A
P
Site 88
S548
A
P
A
S
P
A
P
S
P
A
P
S
P
T
P
Site 89
S552
P
A
P
S
P
A
P
S
P
T
P
A
P
P
Q
Site 90
T554
P
S
P
A
P
S
P
T
P
A
P
P
Q
K
E
Site 91
T567
K
E
Q
P
P
A
E
T
P
T
D
A
A
V
L
Site 92
T575
P
T
D
A
A
V
L
T
S
P
P
A
P
A
P
Site 93
S576
T
D
A
A
V
L
T
S
P
P
A
P
A
P
P
Site 94
T585
P
A
P
A
P
P
V
T
P
S
K
P
M
A
G
Site 95
S587
P
A
P
P
V
T
P
S
K
P
M
A
G
T
T
Site 96
T594
S
K
P
M
A
G
T
T
D
R
E
E
A
T
R
Site 97
S722
I
M
K
R
T
R
K
S
E
V
S
E
T
K
Q
Site 98
S725
R
T
R
K
S
E
V
S
E
T
K
Q
K
Q
D
Site 99
T727
R
K
S
E
V
S
E
T
K
Q
K
Q
D
S
K
Site 100
S741
K
E
A
N
A
N
G
S
S
P
E
P
V
K
A
Site 101
S742
E
A
N
A
N
G
S
S
P
E
P
V
K
A
V
Site 102
S753
V
K
A
V
E
A
R
S
P
G
L
Q
K
E
A
Site 103
S774
I
P
Q
E
P
Q
W
S
L
P
S
K
E
L
P
Site 104
S783
P
S
K
E
L
P
A
S
L
V
N
G
L
Q
P
Site 105
S800
A
H
Q
E
N
G
F
S
T
N
G
P
S
G
D
Site 106
T801
H
Q
E
N
G
F
S
T
N
G
P
S
G
D
K
Site 107
S805
G
F
S
T
N
G
P
S
G
D
K
S
L
S
R
Site 108
S809
N
G
P
S
G
D
K
S
L
S
R
T
P
E
T
Site 109
S811
P
S
G
D
K
S
L
S
R
T
P
E
T
L
L
Site 110
T813
G
D
K
S
L
S
R
T
P
E
T
L
L
P
F
Site 111
T816
S
L
S
R
T
P
E
T
L
L
P
F
A
E
A
Site 112
S834
L
K
K
A
V
V
Q
S
P
Q
V
T
E
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation