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Updated November 2019
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Protein Info
Short Name:
FAM161A
Full Name:
Protein FAM161A
Alias:
Type:
Mass (Da):
76752
Number AA:
660
UniProt ID:
Q3B820
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
L
V
A
S
S
L
Q
T
P
V
N
P
I
T
G
Site 2
T23
Q
T
P
V
N
P
I
T
G
A
R
V
A
Q
Y
Site 3
Y30
T
G
A
R
V
A
Q
Y
E
R
E
D
P
L
K
Site 4
S67
A
S
A
D
L
N
T
S
F
S
G
V
D
E
H
Site 5
S69
A
D
L
N
T
S
F
S
G
V
D
E
H
A
P
Site 6
Y95
I
H
H
S
N
E
E
Y
F
K
K
V
E
E
L
Site 7
S135
P
V
V
I
R
E
D
S
L
S
D
S
S
R
S
Site 8
S137
V
I
R
E
D
S
L
S
D
S
S
R
S
V
S
Site 9
S139
R
E
D
S
L
S
D
S
S
R
S
V
S
E
K
Site 10
S140
E
D
S
L
S
D
S
S
R
S
V
S
E
K
N
Site 11
S142
S
L
S
D
S
S
R
S
V
S
E
K
N
S
Y
Site 12
S144
S
D
S
S
R
S
V
S
E
K
N
S
Y
H
P
Site 13
S148
R
S
V
S
E
K
N
S
Y
H
P
V
S
L
M
Site 14
Y149
S
V
S
E
K
N
S
Y
H
P
V
S
L
M
T
Site 15
S153
K
N
S
Y
H
P
V
S
L
M
T
S
F
S
E
Site 16
S157
H
P
V
S
L
M
T
S
F
S
E
P
D
L
G
Site 17
S159
V
S
L
M
T
S
F
S
E
P
D
L
G
Q
S
Site 18
S166
S
E
P
D
L
G
Q
S
S
S
L
Y
V
S
S
Site 19
S167
E
P
D
L
G
Q
S
S
S
L
Y
V
S
S
S
Site 20
S168
P
D
L
G
Q
S
S
S
L
Y
V
S
S
S
E
Site 21
Y170
L
G
Q
S
S
S
L
Y
V
S
S
S
E
E
E
Site 22
S172
Q
S
S
S
L
Y
V
S
S
S
E
E
E
L
P
Site 23
S173
S
S
S
L
Y
V
S
S
S
E
E
E
L
P
N
Site 24
S174
S
S
L
Y
V
S
S
S
E
E
E
L
P
N
L
Site 25
Y185
L
P
N
L
E
K
E
Y
P
R
K
N
R
M
M
Site 26
T193
P
R
K
N
R
M
M
T
Y
A
K
E
L
I
N
Site 27
Y211
T
D
F
C
V
E
D
Y
I
R
C
K
D
T
G
Site 28
T235
K
R
K
E
W
V
P
T
I
T
V
P
E
P
F
Site 29
S255
E
Q
K
K
K
E
E
S
M
K
S
K
S
D
I
Site 30
S258
K
K
E
E
S
M
K
S
K
S
D
I
E
M
V
Site 31
S260
E
E
S
M
K
S
K
S
D
I
E
M
V
H
K
Site 32
Y278
K
Q
E
E
D
P
E
Y
K
K
K
F
R
A
N
Site 33
S309
Q
K
E
E
R
R
R
S
L
K
E
K
S
K
E
Site 34
S314
R
R
S
L
K
E
K
S
K
E
A
L
L
A
S
Site 35
S321
S
K
E
A
L
L
A
S
Q
K
P
F
K
F
I
Site 36
Y348
Q
L
R
D
F
L
K
Y
K
K
K
T
N
R
F
Site 37
T352
F
L
K
Y
K
K
K
T
N
R
F
K
A
R
P
Site 38
S363
K
A
R
P
I
P
R
S
T
Y
G
S
T
T
N
Site 39
T364
A
R
P
I
P
R
S
T
Y
G
S
T
T
N
D
Site 40
Y365
R
P
I
P
R
S
T
Y
G
S
T
T
N
D
K
Site 41
S367
I
P
R
S
T
Y
G
S
T
T
N
D
K
L
K
Site 42
Y379
K
L
K
E
E
E
L
Y
R
N
L
R
T
Q
L
Site 43
S396
Q
E
H
L
Q
N
S
S
P
L
P
C
R
S
A
Site 44
S402
S
S
P
L
P
C
R
S
A
C
G
C
R
N
P
Site 45
T428
K
H
K
V
R
C
P
T
P
D
F
E
D
L
P
Site 46
Y438
F
E
D
L
P
E
R
Y
Q
K
H
L
S
E
H
Site 47
S443
E
R
Y
Q
K
H
L
S
E
H
K
S
P
K
L
Site 48
S447
K
H
L
S
E
H
K
S
P
K
L
L
T
V
C
Site 49
T452
H
K
S
P
K
L
L
T
V
C
K
P
F
D
L
Site 50
S462
K
P
F
D
L
H
A
S
P
H
A
S
I
K
R
Site 51
S466
L
H
A
S
P
H
A
S
I
K
R
E
K
I
L
Site 52
Y490
L
K
E
T
R
W
P
Y
L
S
P
R
R
K
S
Site 53
S492
E
T
R
W
P
Y
L
S
P
R
R
K
S
P
V
Site 54
S497
Y
L
S
P
R
R
K
S
P
V
R
C
A
G
V
Site 55
T517
N
C
N
P
P
V
P
T
V
S
S
R
G
R
E
Site 56
S519
N
P
P
V
P
T
V
S
S
R
G
R
E
Q
A
Site 57
S520
P
P
V
P
T
V
S
S
R
G
R
E
Q
A
V
Site 58
S530
R
E
Q
A
V
R
K
S
E
K
E
R
M
R
E
Site 59
Y538
E
K
E
R
M
R
E
Y
Q
R
E
L
E
E
R
Site 60
S573
M
A
A
E
K
H
Y
S
N
T
L
K
A
L
G
Site 61
Y598
Q
S
G
K
V
L
E
Y
F
N
N
Q
E
T
K
Site 62
S606
F
N
N
Q
E
T
K
S
V
T
E
D
K
E
S
Site 63
S613
S
V
T
E
D
K
E
S
F
N
E
E
E
K
I
Site 64
Y630
R
E
N
G
E
E
N
Y
F
I
D
T
N
S
Q
Site 65
T634
E
E
N
Y
F
I
D
T
N
S
Q
D
S
Y
K
Site 66
S636
N
Y
F
I
D
T
N
S
Q
D
S
Y
K
E
K
Site 67
Y640
D
T
N
S
Q
D
S
Y
K
E
K
D
E
A
N
Site 68
S650
K
D
E
A
N
E
E
S
E
E
E
K
S
V
E
Site 69
S655
E
E
S
E
E
E
K
S
V
E
E
S
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation