KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TRMT5
Full Name:
tRNA (guanine-N(1)-)-methyltransferase
Alias:
M1G-methyltransferase;tRNA [GM37] methyltransferase;tRNA methyltransferase 5
Type:
Mass (Da):
58246
Number AA:
509
UniProt ID:
Q32P41
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
W
R
P
F
G
F
S
G
R
F
L
K
L
E
Site 2
S21
G
R
F
L
K
L
E
S
H
S
I
T
E
S
K
Site 3
S23
F
L
K
L
E
S
H
S
I
T
E
S
K
S
L
Site 4
T25
K
L
E
S
H
S
I
T
E
S
K
S
L
I
P
Site 5
S27
E
S
H
S
I
T
E
S
K
S
L
I
P
V
A
Site 6
S29
H
S
I
T
E
S
K
S
L
I
P
V
A
W
T
Site 7
S58
L
G
Q
R
K
R
F
S
T
M
P
E
T
E
T
Site 8
T59
G
Q
R
K
R
F
S
T
M
P
E
T
E
T
H
Site 9
T70
T
E
T
H
E
R
E
T
E
L
F
S
P
P
S
Site 10
S74
E
R
E
T
E
L
F
S
P
P
S
D
V
R
G
Site 11
S77
T
E
L
F
S
P
P
S
D
V
R
G
M
T
K
Site 12
T83
P
S
D
V
R
G
M
T
K
L
D
R
T
A
F
Site 13
T88
G
M
T
K
L
D
R
T
A
F
K
K
T
V
N
Site 14
S107
K
V
R
K
E
I
V
S
K
L
M
R
S
L
K
Site 15
S135
E
D
P
E
D
K
E
S
R
L
I
M
L
D
P
Site 16
Y143
R
L
I
M
L
D
P
Y
K
I
F
T
H
D
S
Site 17
S150
Y
K
I
F
T
H
D
S
F
E
K
A
E
L
S
Site 18
S157
S
F
E
K
A
E
L
S
V
L
E
Q
L
N
V
Site 19
S165
V
L
E
Q
L
N
V
S
P
Q
I
S
K
Y
N
Site 20
S169
L
N
V
S
P
Q
I
S
K
Y
N
L
E
L
T
Site 21
T176
S
K
Y
N
L
E
L
T
Y
E
H
F
K
S
E
Site 22
S182
L
T
Y
E
H
F
K
S
E
E
I
L
R
A
V
Site 23
T197
L
P
E
G
Q
D
V
T
S
G
F
S
R
I
G
Site 24
S217
N
L
R
D
H
Q
L
S
F
K
H
L
I
G
Q
Site 25
S235
D
K
N
P
G
I
T
S
A
V
N
K
I
N
N
Site 26
T263
S
G
E
Q
N
M
M
T
K
V
R
E
N
N
Y
Site 27
Y270
T
K
V
R
E
N
N
Y
T
Y
E
F
D
F
S
Site 28
T271
K
V
R
E
N
N
Y
T
Y
E
F
D
F
S
K
Site 29
Y272
V
R
E
N
N
Y
T
Y
E
F
D
F
S
K
V
Site 30
Y280
E
F
D
F
S
K
V
Y
W
N
P
R
L
S
T
Site 31
S286
V
Y
W
N
P
R
L
S
T
E
H
S
R
I
T
Site 32
T287
Y
W
N
P
R
L
S
T
E
H
S
R
I
T
E
Site 33
S290
P
R
L
S
T
E
H
S
R
I
T
E
L
L
K
Site 34
T293
S
T
E
H
S
R
I
T
E
L
L
K
P
G
D
Site 35
T322
P
V
A
K
K
N
C
T
V
F
A
N
D
L
N
Site 36
Y338
E
S
H
K
W
L
L
Y
N
C
K
L
N
K
V
Site 37
S375
L
M
Q
L
L
G
L
S
K
E
R
K
P
S
V
Site 38
S381
L
S
K
E
R
K
P
S
V
H
V
V
M
N
L
Site 39
S420
L
P
I
V
H
C
Y
S
F
S
K
D
A
N
P
Site 40
Y474
Q
I
P
A
S
V
L
Y
K
N
Q
T
R
N
P
Site 41
T478
S
V
L
Y
K
N
Q
T
R
N
P
E
N
H
E
Site 42
T494
P
P
L
K
R
Q
R
T
A
E
A
F
S
D
E
Site 43
S499
Q
R
T
A
E
A
F
S
D
E
K
T
Q
I
V
Site 44
T503
E
A
F
S
D
E
K
T
Q
I
V
S
N
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation