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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL38
Full Name:
Kelch-like protein 38
Alias:
Type:
Mass (Da):
65541
Number AA:
581
UniProt ID:
Q2WGJ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
L
F
K
D
H
D
F
S
S
D
L
L
R
Q
L
Site 2
S18
F
K
D
H
D
F
S
S
D
L
L
R
Q
L
N
Site 3
S26
D
L
L
R
Q
L
N
S
L
R
Q
S
R
I
L
Site 4
S30
Q
L
N
S
L
R
Q
S
R
I
L
T
D
V
S
Site 5
S54
C
H
R
N
V
L
A
S
S
S
P
Y
F
R
A
Site 6
S56
R
N
V
L
A
S
S
S
P
Y
F
R
A
M
F
Site 7
S65
Y
F
R
A
M
F
C
S
S
F
R
E
K
S
E
Site 8
S66
F
R
A
M
F
C
S
S
F
R
E
K
S
E
A
Site 9
S71
C
S
S
F
R
E
K
S
E
A
K
V
Q
L
K
Site 10
T84
L
K
G
I
D
P
P
T
L
D
Q
I
V
S
Y
Site 11
S90
P
T
L
D
Q
I
V
S
Y
V
Y
T
G
E
A
Site 12
Y91
T
L
D
Q
I
V
S
Y
V
Y
T
G
E
A
R
Site 13
S124
P
K
L
F
E
A
C
S
S
Y
L
Q
S
Q
L
Site 14
S125
K
L
F
E
A
C
S
S
Y
L
Q
S
Q
L
A
Site 15
S129
A
C
S
S
Y
L
Q
S
Q
L
A
P
S
N
C
Site 16
S147
I
R
L
S
E
I
L
S
C
E
T
L
K
K
K
Site 17
Y214
D
L
Q
A
R
K
R
Y
M
Q
E
L
F
K
Q
Site 18
Y226
F
K
Q
V
R
L
Q
Y
I
H
P
A
F
F
H
Site 19
S261
T
A
K
R
Q
M
F
S
L
C
G
T
T
V
P
Site 20
S281
L
H
V
P
P
R
N
S
Y
Q
D
F
L
I
L
Site 21
Y282
H
V
P
P
R
N
S
Y
Q
D
F
L
I
L
L
Site 22
S295
L
L
G
G
R
K
D
S
Q
Q
T
T
R
D
V
Site 23
T298
G
R
K
D
S
Q
Q
T
T
R
D
V
L
L
Y
Site 24
T299
R
K
D
S
Q
Q
T
T
R
D
V
L
L
Y
S
Site 25
Y305
T
T
R
D
V
L
L
Y
S
K
Q
T
G
Q
W
Site 26
S314
K
Q
T
G
Q
W
Q
S
L
A
K
L
P
T
R
Site 27
S326
P
T
R
L
Y
K
A
S
A
I
T
L
H
R
S
Site 28
S350
S
S
G
K
S
L
V
S
H
N
V
Y
I
F
S
Site 29
Y374
E
P
M
L
V
A
R
Y
S
H
R
S
T
A
H
Site 30
S375
P
M
L
V
A
R
Y
S
H
R
S
T
A
H
K
Site 31
S378
V
A
R
Y
S
H
R
S
T
A
H
K
N
F
I
Site 32
T379
A
R
Y
S
H
R
S
T
A
H
K
N
F
I
F
Site 33
S400
E
G
Q
E
L
M
G
S
M
E
R
Y
D
S
I
Site 34
Y404
L
M
G
S
M
E
R
Y
D
S
I
C
N
V
W
Site 35
S406
G
S
M
E
R
Y
D
S
I
C
N
V
W
E
S
Site 36
Y434
A
V
K
D
Q
R
L
Y
L
F
G
G
E
D
I
Site 37
Y452
P
V
R
L
I
Q
V
Y
H
I
S
R
N
S
W
Site 38
Y494
Y
T
R
R
I
L
A
Y
D
P
Q
S
N
K
F
Site 39
T517
R
R
M
H
H
G
A
T
V
M
G
N
K
L
Y
Site 40
Y524
T
V
M
G
N
K
L
Y
V
T
G
G
R
R
L
Site 41
T526
M
G
N
K
L
Y
V
T
G
G
R
R
L
T
T
Site 42
T532
V
T
G
G
R
R
L
T
T
D
C
N
I
E
D
Site 43
T533
T
G
G
R
R
L
T
T
D
C
N
I
E
D
S
Site 44
Y546
D
S
A
S
F
D
C
Y
D
P
E
T
D
T
W
Site 45
T552
C
Y
D
P
E
T
D
T
W
T
S
Q
G
Q
L
Site 46
T554
D
P
E
T
D
T
W
T
S
Q
G
Q
L
P
H
Site 47
S555
P
E
T
D
T
W
T
S
Q
G
Q
L
P
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation