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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF4B
Full Name:
Chromosome-associated kinesin KIF4B
Alias:
Chromokinesin-B; Kinesin family member 4B
Type:
Microtubule, Nuclear matrix, Nucleus, Microtubule associated complex protein
Mass (Da):
140035
Number AA:
1234
UniProt ID:
Q2VIQ3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0016363
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003677
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
E
G
C
Q
M
C
L
S
F
V
P
G
E
T
Q
Site 2
Y51
G
T
D
K
S
F
T
Y
D
F
V
F
D
P
C
Site 3
S92
L
A
Y
G
Q
T
G
S
G
K
T
Y
S
M
G
Site 4
T95
G
Q
T
G
S
G
K
T
Y
S
M
G
G
A
Y
Site 5
Y96
Q
T
G
S
G
K
T
Y
S
M
G
G
A
Y
T
Site 6
S97
T
G
S
G
K
T
Y
S
M
G
G
A
Y
T
A
Site 7
T111
A
E
Q
E
N
E
P
T
V
G
I
I
P
R
V
Site 8
S130
F
K
E
I
D
K
K
S
D
F
E
F
T
L
K
Site 9
T135
K
K
S
D
F
E
F
T
L
K
V
S
Y
L
E
Site 10
Y144
K
V
S
Y
L
E
I
Y
N
E
E
I
L
D
L
Site 11
T199
E
Q
G
N
N
S
R
T
V
A
S
T
A
M
N
Site 12
T203
N
S
R
T
V
A
S
T
A
M
N
S
Q
S
S
Site 13
S207
V
A
S
T
A
M
N
S
Q
S
S
R
S
H
A
Site 14
S209
S
T
A
M
N
S
Q
S
S
R
S
H
A
I
F
Site 15
S219
S
H
A
I
F
T
I
S
I
E
Q
R
K
K
S
Site 16
S226
S
I
E
Q
R
K
K
S
D
K
N
C
S
F
R
Site 17
S231
K
K
S
D
K
N
C
S
F
R
S
K
L
H
L
Site 18
S244
H
L
V
D
L
A
G
S
E
R
Q
K
K
T
K
Site 19
S284
L
G
D
D
K
K
G
S
F
V
P
Y
R
D
S
Site 20
Y288
K
K
G
S
F
V
P
Y
R
D
S
K
L
T
R
Site 21
S291
S
F
V
P
Y
R
D
S
K
L
T
R
L
L
Q
Site 22
T294
P
Y
R
D
S
K
L
T
R
L
L
Q
D
S
L
Site 23
S300
L
T
R
L
L
Q
D
S
L
G
G
N
S
H
T
Site 24
S318
A
C
V
S
P
A
D
S
N
L
E
E
T
L
S
Site 25
S325
S
N
L
E
E
T
L
S
T
L
R
Y
A
D
R
Site 26
T326
N
L
E
E
T
L
S
T
L
R
Y
A
D
R
A
Site 27
Y329
E
T
L
S
T
L
R
Y
A
D
R
A
R
K
I
Site 28
T348
I
V
N
I
D
P
H
T
A
E
L
N
H
L
K
Site 29
S376
H
G
G
T
L
P
G
S
I
N
A
E
P
S
E
Site 30
S382
G
S
I
N
A
E
P
S
E
N
L
Q
S
L
M
Site 31
S387
E
P
S
E
N
L
Q
S
L
M
E
K
N
Q
S
Site 32
S394
S
L
M
E
K
N
Q
S
L
V
E
E
N
E
K
Site 33
S403
V
E
E
N
E
K
L
S
R
C
L
S
K
A
A
Site 34
S407
E
K
L
S
R
C
L
S
K
A
A
G
Q
T
A
Site 35
T474
C
N
L
Q
Q
L
I
T
Q
L
S
D
E
T
V
Site 36
S477
Q
Q
L
I
T
Q
L
S
D
E
T
V
A
C
T
Site 37
T480
I
T
Q
L
S
D
E
T
V
A
C
T
A
A
A
Site 38
T490
C
T
A
A
A
I
D
T
A
V
E
E
E
A
Q
Site 39
T500
E
E
E
A
Q
V
E
T
S
P
E
T
S
R
S
Site 40
S501
E
E
A
Q
V
E
T
S
P
E
T
S
R
S
S
Site 41
T504
Q
V
E
T
S
P
E
T
S
R
S
S
D
A
F
Site 42
S505
V
E
T
S
P
E
T
S
R
S
S
D
A
F
T
Site 43
S507
T
S
P
E
T
S
R
S
S
D
A
F
T
T
Q
Site 44
S508
S
P
E
T
S
R
S
S
D
A
F
T
T
Q
H
Site 45
T512
S
R
S
S
D
A
F
T
T
Q
H
A
L
H
Q
Site 46
T544
E
A
L
V
R
K
M
T
Q
N
D
N
Q
L
Q
Site 47
Y557
L
Q
P
I
Q
F
Q
Y
Q
D
N
I
K
N
L
Site 48
S628
K
L
L
K
L
K
E
S
T
E
R
T
V
S
K
Site 49
T629
L
L
K
L
K
E
S
T
E
R
T
V
S
K
L
Site 50
T632
L
K
E
S
T
E
R
T
V
S
K
L
N
Q
E
Site 51
S634
E
S
T
E
R
T
V
S
K
L
N
Q
E
I
W
Site 52
Y684
E
R
D
R
K
R
Q
Y
E
L
L
K
L
E
R
Site 53
S698
R
N
F
Q
K
Q
S
S
V
L
R
R
K
T
E
Site 54
T704
S
S
V
L
R
R
K
T
E
E
A
A
A
A
N
Site 55
T725
L
Q
K
Q
R
E
V
T
D
K
R
K
E
T
Q
Site 56
T731
V
T
D
K
R
K
E
T
Q
S
H
G
K
E
G
Site 57
S733
D
K
R
K
E
T
Q
S
H
G
K
E
G
I
A
Site 58
S756
N
E
I
E
V
M
V
S
T
E
E
A
K
R
H
Site 59
T799
P
P
K
L
R
K
C
T
F
S
L
S
E
V
H
Site 60
S801
K
L
R
K
C
T
F
S
L
S
E
V
H
G
Q
Site 61
S803
R
K
C
T
F
S
L
S
E
V
H
G
Q
V
L
Site 62
T817
L
E
S
E
D
C
I
T
K
Q
I
E
S
L
E
Site 63
T825
K
Q
I
E
S
L
E
T
E
M
E
L
R
S
A
Site 64
S846
Q
K
L
L
D
A
E
S
E
D
R
P
K
Q
C
Site 65
Y869
E
A
K
C
A
L
K
Y
L
I
G
E
L
V
S
Site 66
S876
Y
L
I
G
E
L
V
S
S
K
I
H
V
T
K
Site 67
S877
L
I
G
E
L
V
S
S
K
I
H
V
T
K
L
Site 68
S887
H
V
T
K
L
E
N
S
L
R
Q
S
K
A
S
Site 69
S891
L
E
N
S
L
R
Q
S
K
A
S
C
A
D
M
Site 70
S894
S
L
R
Q
S
K
A
S
C
A
D
M
Q
K
M
Site 71
Y933
Q
H
Q
E
K
V
L
Y
L
V
S
Q
L
Q
E
Site 72
S936
E
K
V
L
Y
L
V
S
Q
L
Q
E
S
Q
M
Site 73
S951
A
E
K
Q
L
E
K
S
A
S
E
K
E
Q
Q
Site 74
S953
K
Q
L
E
K
S
A
S
E
K
E
Q
Q
L
V
Site 75
S1001
L
I
L
L
Q
V
A
S
R
Q
K
H
L
P
N
Site 76
T1010
Q
K
H
L
P
N
D
T
L
L
S
P
D
S
S
Site 77
S1013
L
P
N
D
T
L
L
S
P
D
S
S
F
E
Y
Site 78
S1016
D
T
L
L
S
P
D
S
S
F
E
Y
I
P
P
Site 79
S1017
T
L
L
S
P
D
S
S
F
E
Y
I
P
P
K
Site 80
Y1020
S
P
D
S
S
F
E
Y
I
P
P
K
P
K
P
Site 81
S1028
I
P
P
K
P
K
P
S
R
V
K
E
K
F
L
Site 82
S1038
K
E
K
F
L
E
Q
S
M
D
I
E
D
L
K
Site 83
Y1046
M
D
I
E
D
L
K
Y
C
S
E
H
S
V
N
Site 84
S1048
I
E
D
L
K
Y
C
S
E
H
S
V
N
E
H
Site 85
S1051
L
K
Y
C
S
E
H
S
V
N
E
H
E
D
G
Site 86
S1064
D
G
D
G
D
G
D
S
D
E
G
D
D
E
E
Site 87
T1075
D
D
E
E
W
K
P
T
K
L
V
K
V
S
R
Site 88
S1106
C
G
C
R
K
Q
K
S
D
C
G
V
D
C
S
Site 89
S1113
S
D
C
G
V
D
C
S
C
D
P
T
K
C
R
Site 90
T1117
V
D
C
S
C
D
P
T
K
C
R
N
R
Q
Q
Site 91
S1128
N
R
Q
Q
G
K
D
S
L
G
T
V
E
Q
T
Site 92
T1131
Q
G
K
D
S
L
G
T
V
E
Q
T
Q
D
S
Site 93
T1135
S
L
G
T
V
E
Q
T
Q
D
S
E
G
S
F
Site 94
S1141
Q
T
Q
D
S
E
G
S
F
K
L
E
D
P
T
Site 95
T1148
S
F
K
L
E
D
P
T
E
V
T
P
G
L
S
Site 96
T1151
L
E
D
P
T
E
V
T
P
G
L
S
F
F
N
Site 97
T1163
F
F
N
P
V
C
A
T
P
N
S
K
I
L
K
Site 98
S1180
C
D
M
E
Q
V
L
S
K
K
T
A
P
A
P
Site 99
T1183
E
Q
V
L
S
K
K
T
A
P
A
P
S
P
F
Site 100
S1188
K
K
T
A
P
A
P
S
P
F
D
L
P
E
S
Site 101
S1195
S
P
F
D
L
P
E
S
K
H
G
A
T
E
Y
Site 102
Y1202
S
K
H
G
A
T
E
Y
Q
Q
N
K
P
P
G
Site 103
S1218
K
K
K
R
A
L
A
S
N
T
S
F
F
S
G
Site 104
T1220
K
R
A
L
A
S
N
T
S
F
F
S
G
C
S
Site 105
S1221
R
A
L
A
S
N
T
S
F
F
S
G
C
S
P
Site 106
S1224
A
S
N
T
S
F
F
S
G
C
S
P
I
E
E
Site 107
S1227
T
S
F
F
S
G
C
S
P
I
E
E
E
A
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation